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Hemin chloride

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Identification
Molecular formula
C34H32ClFeN4O4
CAS number
16009-13-5
IUPAC name
ferrous;3-[18-(2-carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-porphyrin-21,24-diid-2-yl]propanoic acid
State
State

At room temperature, Hemin chloride is a solid. It maintains its structure as a crystalline substance, resisting dissolution in water but soluble in alkaline solutions and organic solvents.

Melting point (Celsius)
300.00
Melting point (Kelvin)
573.15
Boiling point (Celsius)
362.85
Boiling point (Kelvin)
636.00
General information
Molecular weight
651.94g/mol
Molar mass
651.9400g/mol
Density
2.3700g/cm3
Appearence

Hemin chloride appears as a red-brown to dark brown crystalline solid. It is a porphyrin complex with an iron center, giving it a characteristic metallic sheen due to its crystalline structure.

Comment on solubility

Solubility of Ferrous 3-[18-(2-Carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-porphyrin-21,24-diid-2-yl]propanoic Acid

The solubility of ferrous 3-[18-(2-carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-porphyrin-21,24-diid-2-yl]propanoic acid can be quite intriguing due to its complex structure that features both hydrophilic and hydrophobic regions. Here are a few key points regarding its solubility:

  • Hydrophilicity: The presence of the carboxyethyl group contributes to the compound's ability to interact favorably with polar solvents, enhancing its solubility in water.
  • Hydrophobicity: The tetramethyl and divinyl components introduce significant hydrophobic characteristics, which may limit solubility in aqueous environments.
  • Solvent Compatibility: This compound may exhibit higher solubility in organic solvents such as chloroform or acetone due to the hydrophobic substructures.
  • Temperature Effects: Increasing temperature can generally enhance solubility for many organic compounds, though specific studies are necessary to confirm this for ferrous 3-[18-(2-carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-porphyrin-21,24-diid-2-yl]propanoic acid.

Overall, the solubility of this compound is influenced by its intricate structure, and understanding these characteristics is essential for practical applications in various chemical and biological systems.

Interesting facts

Interesting Facts about Ferrous 3-[18-(2-Carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-porphyrin-21,24-diid-2-yl]propanoic Acid

Ferrous 3-[18-(2-carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-porphyrin-21,24-diid-2-yl]propanoic acid is a fascinating chemical compound, particularly within the realm of coordination chemistry and biochemistry. Here are some intriguing aspects of this compound:

  • Role in Biological Systems: Ferrous compounds play a critical role in biological systems, especially in oxygen transport. Hemoglobin, the molecule responsible for oxygen delivery in blood, contains iron in the ferrous state.
  • Porphyrin Structure: This compound features a porphyrin ring, which is known for its ability to form stable complexes with various metals. The unique structure contributes to its reactivity and potential utility in various chemical reactions.
  • Applications in Medicine: Due to its structural similarities to heme, ferrous porphyrins are explored as *potential therapeutic agents*. These compounds may have applications in drug delivery systems or as catalysts in biological reactions.
  • Electrochemical Properties: The ferrous state can undergo oxidation to ferric, making this compound significant in electrochemical reactions. This property is exploited in sensors and other electronic applications.
  • Synthetic Challenges: The synthesis of such complex molecules requires careful consideration of reaction conditions and precursor selection, highlighting the blend of organic chemistry and materials science involved in their creation.

Overall, ferrous 3-[18-(2-carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-porphyrin-21,24-diid-2-yl]propanoic acid underscores the intersection of chemistry with fields such as biology and medicine, embodying the quest for innovation through molecular design. As one researcher noted, *"The beauty of chemistry lies not just in its elements, but in the intricate dance of bonds and reactions."*

Synonyms
heme
protoheme
14875-96-8
Ferroheme
heme b
ferroprotoporphyrin
Reduced hematin
Haem
protoheme IX
Ferroprotoporphyrin IX
Iron protoporphyrin ix
Protohaem
Ferrous protoheme
Iron protoporphyrin
Ferrous protoheme IX
42VZT0U6YR
Iron(II) protoporphyrin IX
hemin
Normosang
3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid;iron(2+)
Protoheme IX (VAN)
Ferroheme (VAN)
Heme (VAN)
UNII-42VZT0U6YR
NSC 16669
GLOBIFER
NSC 267100
HUMAN HEMIN
HEME IRON
HEME [MI]
C.I. Solvent Yellow 162
Heme iron polypeptide(Hematin)
GTPL4349
orb1298501
SCHEMBL29359512
SCHEMBL30123204
SCHEMBL31123514
PAA87596
MSK157449
Ferrate(2-), (7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N21,N22,N23,N24)-, dihydrogen, (SP-4-2)-
85758-EP2270016A1
85758-EP2270505A1
85758-EP2305243A1
85758-EP2305825A1
Q620084
Iron, (dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(2-))-
[7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N^21,N^22,N^23,N^24]-ferrate(2-)dihydrogen
3-[18-(2-carboxyethyl)-3,8,13,17-tetramethyl-7,12-divinyl-porphyrin-21,23-diid-2-yl]propanoic acid
Ferrate(2-), (7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-kappaN21,kappaN22,kappaN23,kappaN24)-, dihydrogen, (SP-4-2)-
Ferrate(2-), (7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-kappaN21,kappaN22,kappaN23,kappaN24)-, hydrogen (1:2), (SP-4-2)-
ferrous 3-[(1Z,4Z,9Z,15Z)-18-(2-carboxyethyl)-3,7,12,17-tetramethyl-8,13-divinyl-21,23-dihydroporphyrin-2-yl]propanoic acid