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Formohydrazide

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Identification
Molecular formula
CH4N2O
CAS number
624-84-0
IUPAC name
formohydrazide
State
State

Formohydrazide exists as a solid at room temperature, typically appearing as a crystalline powder.

Melting point (Celsius)
54.00
Melting point (Kelvin)
327.00
Boiling point (Celsius)
148.00
Boiling point (Kelvin)
421.00
General information
Molecular weight
46.06g/mol
Molar mass
46.0550g/mol
Density
1.4200g/cm3
Appearence

Formohydrazide is a colorless solid with a crystalline texture. It has the appearance of a typical crystalline powder, which is white or nearly white in color.

Comment on solubility

Solubility of Formohydrazide

Formohydrazide, with the chemical formula CH2N2O, exhibits interesting solubility characteristics. As a small organic compound, it is known for its ability to dissolve in various solvents. Here are some key points regarding its solubility:

  • Water Solubility: Formohydrazide is highly soluble in water due to the presence of hydrophilic functional groups that can interact favorably with water molecules.
  • Polar Solvents: In addition to water, it also shows solubility in polar organic solvents such as methanol and ethanol, which assist in stabilizing its molecular structure through dipole interactions.
  • Non-Polar Solvents: Conversely, its solubility decreases significantly in non-polar solvents like hexane or benzene, indicating a lack of favorable interactions with non-polar molecules.
  • Temperature Dependency: The solubility of formohydrazide may vary with temperature; generally, higher temperatures can increase solubility in many solvents.

The versatility in solubility of formohydrazide can be summed up as:

"High solubility in polar solvents, especially in water, with decreased solubility in non-polar solvents."

This solubility profile makes formohydrazide a useful compound in various chemical applications and reactions.

Interesting facts

Interesting Facts about Formohydrazide

Formohydrazide is a fascinating chemical compound that holds significance in both synthetic and biological contexts. Here are some engaging aspects of this intriguing molecule:

  • Versatile Reagent: Formohydrazide serves as a valuable reagent in organic synthesis. It is commonly utilized in hydrazone formations, which are pivotal in developing various pharmaceuticals and agrochemicals.
  • Increased Reactivity: The amino group in formohydrazide enhances its reactivity, making it a crucial intermediate in the preparation of more complex hydrazines, and discerning the functionalities of nitrogen-containing compounds.
  • Biological Importance: The compound has been studied for its potential applications in the realm of biochemistry, where it can act as a mode of nitrogen transfer in certain enzymatic reactions.
  • Historical Significance: Formohydrazide has a rich history in chemical research, with its synthesis dating back to earlier studies focused on nitrogen compounds, which were pivotal in the development of many modern chemical methodologies.
  • Environmental Considerations: Given its applications, researchers are exploring more sustainable routes to synthesize formohydrazide, promoting greener chemistry principles to minimize environmental impact.

In summary, formohydrazide is not just an ordinary compound; its reactivity, applications, and contributions to both the chemical community and biological research make it a noteworthy subject of study in contemporary chemistry.

Synonyms
Formylhydrazine
Formohydrazide
Formic hydrazide
Hydrazinecarboxaldehyde
N-FORMYLHYDRAZINE
Formylhydrazide
Formhydrazide
Carbazaldehyde
Hydrazine, formyl-
Formal hydrazine
Formhydrazid
Formylhydrazid
Formic acid, hydrazide
Formhydrazid [German]
NSC 72391
UNII-V1D8X13QFN
EINECS 210-867-9
V1D8X13QFN
BRN 0635759
AI3-61912
Hydrazinecarboxaldehyde-
NSC-72391
DTXSID6020642
XZBIXDPGRMLSTC-UHFFFAOYSA-
4-02-00-00085 (Beilstein Handbook Reference)
DTXCID00642
210-867-9
inchi=1/ch4n2o/c2-3-1-4/h1h,2h2,(h,3,4)
xzbixdpgrmlstc-uhfffaoysa-n
624-84-0
Formic acid hydrazide
MFCD00007589
formyl hydrazine
Formohydrazide; Formylhydrazide; Formylhydrazine; Monoformylhydrazine; N-Formylhydrazine; NSC 72391
CH4N2O
formyl-hydrazine
N-formyl-hydrazine
NH2NHCHO
WLN: ZMVH
BCP26005
NSC72391
AKOS009031403
Formic acid hydrazide;Formic hydrazide
AB00881
DB-013439
F0667
NS00035048
EN300-20700
6F-930
F11944
Q24205358
F1905-7097