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3-Furoic acid

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Identification
Molecular formula
C5H4O3
CAS number
488-93-7
IUPAC name
furan-3-carboxylic acid
State
State

At room temperature, 3-Furoic acid is typically in a solid state.

Melting point (Celsius)
132.00
Melting point (Kelvin)
405.15
Boiling point (Celsius)
248.00
Boiling point (Kelvin)
521.15
General information
Molecular weight
112.09g/mol
Molar mass
112.0870g/mol
Density
1.2450g/cm3
Appearence

3-Furoic acid appears as a white to off-white crystalline powder. It has a characteristic odor and may yellow slightly on prolonged exposure to light.

Comment on solubility

Solubility of Furan-3-carboxylic Acid

Furan-3-carboxylic acid, known for its unique structure, exhibits noteworthy solubility characteristics. The solubility of this compound can be influenced by several factors, including temperature, pH, and the solvent in question.

Key Solubility Insights:

  • Polar Solvents: Furan-3-carboxylic acid is generally soluble in polar solvents such as water and alcohols. This solubility is attributed to the presence of the carboxylic acid functional group, which can form hydrogen bonds with the solvent molecules.
  • Nonpolar Solvents: In contrast, its solubility in nonpolar solvents is quite limited. The aromatic nature of the furan ring contributes to this behavior, as nonpolar interactions are less favorable.
  • Temperature Dependence: The solubility of Furan-3-carboxylic acid tends to increase with temperature, making it more soluble in hot solvents compared to cold ones.

As a general rule, it can be stated that:

  • If you're working with water, expect good solubility.
  • For organic solvents, solubility may vary, so testing is recommended.

Understanding the solubility of Furan-3-carboxylic acid is crucial for applications in organic synthesis and pharmaceuticals, where the compound's behavior in various environments may greatly impact its efficacy and usability.

Interesting facts

Interesting Facts About Furan-3-carboxylic Acid

Furan-3-carboxylic acid is an intriguing compound with numerous applications in organic chemistry and materials science. This compound can be characterized by its unique structure, which incorporates both a furan ring and a carboxylic acid functional group. Here are some fascinating aspects about this compound:

  • Natural Occurrence: Furan derivatives are commonly found in many natural products, including plant metabolites. The presence of furan-3-carboxylic acid suggests that it may play a role in various biochemical pathways.
  • Precursor in Synthesis: This compound serves as an important intermediate in the synthesis of pharmaceuticals and agricultural chemicals. It helps in the development of compounds that have enhanced biological activity.
  • Versatile Reactions: Furan-3-carboxylic acid can undergo a variety of chemical reactions. These reactions can include cyclization, esterification, and amidation, making it a versatile building block for chemists.
  • Research Potential: There has been growing interest in furan-3-carboxylic acid for its potential applications in the synthesis of novel polymers and materials. Its unique properties may lead to advancements in green chemistry and sustainable materials.
  • Correlating with Bioactivity: Some studies suggest that furan-3-carboxylic acid derivatives exhibit interesting biological activities, which may include anti-inflammatory and antimicrobial properties, thus inviting further investigation for medicinal use.

The integration of furan-3-carboxylic acid into various chemical processes highlights its significance in both academic research and industrial applications. As we continue to explore the chemistry of this compound, we may uncover new avenues that bolster our understanding of organic synthesis and compound reactivity.

Synonyms
3-FUROIC ACID
furan-3-carboxylic acid
488-93-7
3-Furancarboxylic acid
3-carboxyfuran
88A3S7RG98
EINECS 207-689-9
NSC 349941
NSC-349941
CHEBI:30846
DTXSID50197611
3-Furancarboxylic acid (9CI)
DTXCID10120102
207-689-9
3-Furanoic acid
MFCD00005350
UNII-88A3S7RG98
3-Furancarboxylic Acid; 3-Carboxyfuran; 3-Furanoic Acid; NSC 349941
3-Furanoate
3-FUROICACID
3-furan carboxylic acid
3-Furoic acid, 98%
Furan-3 -carboxylic acid
bmse000842
SCHEMBL142183
ALBB-005990
BCP26912
CS-D0170
BBL025800
GEO-01450
NSC349941
s6097
STK503655
AKOS000121066
AC-4439
FF03625
PB30525
PS-4247
SB20113
BP-13035
HY-21075
PD124066
SY003999
3-Furancarboxylic acid; 3-furoyl chloride
3-Furoic acid, purum, >=98.0% (T)
DB-028511
F0304
NS00015313
EN300-23735
Furan-3-carboxylic acid;3-Furancarboxylic acid
F2191-0244
Z164706016
InChI=1/C5H4O3/c6-5(7)4-1-2-8-3-4/h1-3H,(H,6,7