Skip to main content

1-Hexadecanethiol

ADVERTISEMENT
Identification
Molecular formula
C16H34S
CAS number
2917-26-2
IUPAC name
hexadecane-1-thiol
State
State

At room temperature, 1-Hexadecanethiol is in a liquid state, although it may solidify upon cooling to just below room temperature.

Melting point (Celsius)
19.50
Melting point (Kelvin)
292.65
Boiling point (Celsius)
331.00
Boiling point (Kelvin)
604.15
General information
Molecular weight
258.52g/mol
Molar mass
0.0000g/mol
Density
0.8375g/cm3
Appearence

1-Hexadecanethiol is typically a clear or slightly yellow liquid. It has a characteristic odor that is often described as unpleasant and sulfurous.

Comment on solubility

Solubility of Hexadecane-1-thiol

Hexadecane-1-thiol, with the chemical formula CH3(CH2)14SH, exhibits unique solubility characteristics that stem from its long hydrocarbon chain and thiol functional group. Here are some key points regarding its solubility:

  • Solvent Compatibility: Hexadecane-1-thiol is primarily insoluble in water due to the dominant hydrophobic nature of the long alkyl chain. Water molecules struggle to interact with the extensive nonpolar region, making hexadecane-1-thiol poorly soluble.
  • Solubility in Organic Solvents: In contrast, hexadecane-1-thiol is soluble in various organic solvents, including ethanol, benzene, and chloroform. This behavior is attributed to favorable interactions between the thiol group and the solvent molecules.
  • Self-assembly Properties: When in solution, hexadecane-1-thiol can participate in self-assembly processes, leading to the formation of micelles or other ordered structures, especially in nonpolar solvents.
  • Temperature Dependence: Solubility can be affected by temperature changes; generally, higher temperatures may increase solubility in organic solvents.

In summary, the solubility of hexadecane-1-thiol is a fascinating example of the balance between hydrophobic and polar interactions, illustrating the complex behavior of thiols with long-chain hydrocarbons.

Interesting facts

Interesting Facts About Hexadecane-1-thiol

Hexadecane-1-thiol is a fascinating compound that falls under the category of thiols, characterized by the presence of a sulfur atom bonded to a carbon atom. This compound has stirred interest in various scientific fields due to its unique properties and applications.

Key Characteristics and Applications:

  • Biological Significance: Hexadecane-1-thiol plays a role in biological systems, particularly in cell membranes where it can influence membrane fluidity and signaling.
  • Self-Assembled Monolayers (SAMs): It is widely studied for its ability to form Self-Assembled Monolayers on gold surfaces, which are crucial for sensor applications and nanotechnology.
  • Surface Modification: This compound is often used in surface modification, helping to tailor the properties of materials for specific functions, such as improved adhesion or chemical reactivity.
  • Chemical Reagent: As a thiol, hexadecane-1-thiol can participate in various chemical reactions, making it a valuable reagent in organic synthesis.

Fun Facts:

  • Hexadecane-1-thiol is a long-chain alkane, which contributes to its hydrophobic characteristics.
  • This compound can be used in the creation of superhydrophobic surfaces, providing insights into water-repellant technologies.
  • Its structural properties enable it to be studied in the development of new biomaterials and drug delivery systems.

In conclusion, hexadecane-1-thiol is more than just a simple compound; it acts as a bridge connecting chemistry to biology and materials science. The ongoing research surrounding thiols like hexadecane-1-thiol invites us to explore new frontiers in innovation and technology.

Synonyms
1-HEXADECANETHIOL
hexadecane-1-thiol
Hexadecanethiol
Cetyl mercaptan
Cetylmercaptan
UNII-QR98QIO1QL
QR98QIO1QL
EINECS 220-846-6
NSC-57866
DTXSID6062709
NSC-229611
Hexadecanethiol-1
nHexadecanethiol
Hexadecanethiol1
NSC 229611
DTXCID0037946
ortrwbybjvgvqc-uhfffaoysa-n
2917-26-2
n-Hexadecanethiol
n-Hexadecyl mercaptan
Hexadecyl mercaptan
1-Cetanethiol
hexadecylthiol
n-hexadecylthiol
22208-70-4
1-Mercaptohexadecane
MFCD00011677
NSC 57866
1-Hexadecanethiol, 99%
SCHEMBL51190
NSC57866
NSC229568
AKOS015897657
1-Hexadecanethiol, >=95.0% (GC)
FH36426
NSC-229568
BP-20993
LS-14547
DB-068078
H0068
NS00021994
G68010
Q424840