Interesting facts
Interesting Facts about Hexadecyl-[2-[(4-methoxyphenyl)methyl-pyrimidin-2-yl-amino]ethyl]-dimethyl-ammonium Bromide
This compound, often referred to in the scientific community by its shorter name, is a fascinating quaternary ammonium salt that combines a variety of chemical functionalities. Here are some intriguing aspects:
- Structure and Functionality: The intriguing structure of this compound features a long hydrophobic hexadecyl chain coupled with a pyrimidinyl group. This combination gives it amphiphilic properties, which allows it to interact in diverse environments, making it particularly useful in various applications.
- Biological Significance: Compounds containing pyrimidine derivatives are often explored for their bioactivity. They serve as a foundation for numerous pharmaceutical agents and can exhibit significant antibacterial, antifungal, and anticancer properties. The inclusion of dimethylamino groups adds to its potential eukaryotic cellular activity.
- Application in Drug Delivery: Its quaternary ammonium nature enables this compound to act as a potential surfactant and stabilizing agent in drug delivery systems, aiding in transporting hydrophobic drugs across biological membranes.
- Surface Activity: The compound’s quaternary ammonium structure can modify surface tension and improve emulsion stability, making it valuable in formulations such as cosmetics and pharmaceuticals.
- Research and Development: Ongoing research aims to uncover new applications for this compound. Its ability to enhance solubility and bioavailability of drugs hints at its importance in drug formulation sciences.
As a reminder, the broad range of potential uses for hexadecyl-[2-[(4-methoxyphenyl)methyl-pyrimidin-2-yl-amino]ethyl]-dimethyl-ammonium bromide showcases the beauty of chemistry and its role in advancing medical and technological fields. The interplay of its hydrophobic and hydrophilic regions makes it a prime candidate for studies in nanotechnology and molecular biology.
Synonyms
THONZONIUM BROMIDE
Thonzide
Tonzonium bromide
Tonzonium bromide [INN]
UNII-JI2B19CR0R
NSC-5648
Thonzonium bromide [USAN]
JI2B19CR0R
Thonzide (TN)
Tonzonii bromidum [INN-Latin]
Thonzonium bromide [USAN:USP]
DTXSID1045326
Bromure de tonzonium [INN-French]
Bromuro de tonzonio [INN-Spanish]
NSC 5648
Tonzonium bromide (INN)
EINECS 209-032-1
Thonzonium Bromide (USAN)
NC-1264
THONZONIUM BROMIDE [MI]
DTXCID9025326
NSC5648
THONZONIUM BROMIDE [VANDF]
TONZONIUM BROMIDE [MART.]
TONZONIUM BROMIDE [WHO-DD]
THONZONIUM BROMIDE [USP-RS]
Hexadecyl(2-((p-methoxybenzyl)-2-pyrimidinylamino)ethyl)dimethylammonium bromide
THONZONIUM BROMIDE [ORANGE BOOK]
Hexadecyl(2-[(p-methoxybenzyl)-2-pyrimidinylamino]ethyl)dimethylammonium bromide
COLY-MYCIN S COMPONENT THONZONIUM BROMIDE
1-Hexadecanaminium, N-(2-(((4-methoxyphenyl)methyl)-2-pyrimidinylamino)ethyl)-N,N-dimethyl-, bromide
Tonzonii bromidum (INN-Latin)
Thonzonium bromide (USAN:USP)
TONZONIUM BROMIDE (MART.)
Bromure de tonzonium (INN-French)
Bromuro de tonzonio (INN-Spanish)
THONZONIUM BROMIDE (USP-RS)
tonzonio bromuro
Hexadecyl[2-[(p-methoxybenzyl)-2-pyrimidinylamino]ethyl]dimethylammonium bromide
THONZONIUM BROMIDE COMPONENT OF COLY-MYCIN S
553-08-2
Thonzonium (bromide)
Bromuro de tonzonio
Bromure de tonzonium
NC 1264
HEXADECYL[2-([P-METHOXYBENZYL]-2-PYRIMIDINYLAMINO)ETHYL]DIMETHYL-AMMONIUM BROMIDE
hexadecyl-[2-[(4-methoxyphenyl)methyl-pyrimidin-2-ylamino]ethyl]-dimethylazanium;bromide
MLS002154065
SMR001233380
N-(2-((4-Methoxybenzyl)(pyrimidin-2-yl)amino)ethyl)-N,N-dimethylhexadecan-1-aminium bromide
Tonzonii bromidum
SR-01000841261
NCGC00016507-01
CAS-553-08-2
Tonzoniumbromid
Nebair
SCHEMBL60801
REGID_for_CID_11102
CHEMBL1200883
HY-B1246R
Thonzonium (bromide) (Standard)
WBWDWFZTSDZAIG-UHFFFAOYSA-M
HMS1570J12
HMS2097J12
HMS2234H11
HMS3714J12
Pharmakon1600-01503873
HY-B1246
Tox21_110463
EX-A11185
MFCD00133855
NSC760359
AKOS026750378
Tox21_110463_1
CCG-213228
CS-4957
NSC-760359
SB60438
NCGC00016507-05
DA-58537
MS-30532
NS00044022
D02140
F85275
EN300-18386592
Q7795979
SR-01000841261-2
SR-01000841261-3
Cetyl[2-[(p-methoxybenzyl)-2-pyrimidinylamino]ethyl]dimethylammonium bromide
Ammonium, hexadecyl(2-((p-methoxybenzyl)-2-pyrimidinylamino)ethyl)dimethyl-, bromide
hexadecyl(2-{[(4-methoxyphenyl)methyl](pyrimidin-2-yl)amino}ethyl)dimethylazanium bromide
Solubility of Hexadecyl-[2-[(4-methoxyphenyl)methyl-pyrimidin-2-yl-amino]ethyl]-dimethyl-ammonium Bromide
The solubility of the compound hexadecyl-[2-[(4-methoxyphenyl)methyl-pyrimidin-2-yl-amino]ethyl]-dimethyl-ammonium bromide can be characterized by several important factors:
1. Solubility in Water
This compound is expected to have limited solubility in water due to its long hydrophobic hexadecyl chain. Typically, larger alkyl chains contribute to decreased water solubility, making such ammonium compounds less soluble. Nevertheless, the presence of the pyrimidine ring and the quaternary ammonium group may permit some interaction with water molecules through dipole interactions.
2. Solubility in Organic Solvents
On the other hand, hexadecyl-[2-[(4-methoxyphenyl)methyl-pyrimidin-2-yl-amino]ethyl]-dimethyl-ammonium bromide is likely to be:
3. Temperature Effects
It is also important to consider that solubility can vary with temperature:
In conclusion, while hexadecyl-[2-[(4-methoxyphenyl)methyl-pyrimidin-2-yl-amino]ethyl]-dimethyl-ammonium bromide might struggle with water solubility, its characteristics suggest a favorable interaction with organic solvents, highlighting the importance of its structural components in determining dissolution properties.