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Cetyltrimethylammonium chloride

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Identification
Molecular formula
C19H34ClN
CAS number
112-02-7
IUPAC name
hexadecylammonium;chloride
State
State

At room temperature, cetyltrimethylammonium chloride exists as a solid. It remains stable in this form under typical environmental conditions.

Melting point (Celsius)
245.00
Melting point (Kelvin)
518.00
Boiling point (Celsius)
360.00
Boiling point (Kelvin)
633.00
General information
Molecular weight
319.96g/mol
Molar mass
364.4510g/mol
Density
0.9680g/cm3
Appearence

Cetyltrimethylammonium chloride appears as a white crystalline powder. The compound is known for its effectiveness in various chemical formulations, appearing dry and granular in form.

Comment on solubility

Solubility of Hexadecylammonium Chloride

Hexadecylammonium chloride (C16H34ClN) is a quaternary ammonium salt that exhibits unique solubility properties due to its long hydrophobic hydrocarbon tail and its polar ammonium head. When discussing the solubility of this compound, several key points emerge:

  • Polar and Non-Polar Interactions: The long aliphatic chain makes hexadecylammonium chloride more soluble in non-polar solvents like oils and organic solvents, while the chloride ion interacts favorably with polar solvents.
  • Water Solubility: Despite its ionic nature, hexadecylammonium chloride has limited solubility in water due to the competing effects of hydrophobic interactions. As the hydrocarbon chain length increases, the solubility in water tends to decrease.
  • Concentration Effects: Hexadecylammonium chloride can form micelles in higher concentrations, leading to enhanced solubility in aqueous solutions under specific conditions.
  • Temperature Influence: The solubility of hexadecylammonium chloride can be significantly influenced by temperature changes, where increased temperatures typically result in higher solubility.

In summary, while hexadecylammonium chloride is not highly soluble in water, its solubility characteristics are governed by a balance of its polar and hydrophobic components. It serves as a fascinating example of how molecular structure can directly impact solubility behavior in various environments.

Interesting facts

Interesting Facts about Hexadecylammonium Chloride

Hexadecylammonium chloride, often referred to as cetylammonium chloride, is a fascinating compound notable for its unique properties and diverse applications. Here are some engaging facts:

  • Amphiphilic Nature: As a quaternary ammonium salt, this compound displays both hydrophobic (water-repelling) and hydrophilic (water-attracting) characteristics, making it an excellent surfactant. This dual property allows it to form micelles in solution, which are crucial in various cleaning and emulsifying processes.
  • Application in Industry: Hexadecylammonium chloride is widely used in the production of cosmetics and pharmaceuticals, acting as a conditioning agent and preservative. Its efficacy in reducing surface tension is particularly valuable in formulations like lotions and creams.
  • Biological Significance: Due to its cationic nature, this compound can interact with negatively charged biological membranes, making it useful in antimicrobial applications. It’s been studied for its potential to disrupt bacterial membranes, which can enhance its effectiveness in combating pathogens.
  • Environmental Impact: While effective, the use of quaternary ammonium compounds like hexadecylammonium chloride raises concerns regarding their environmental stability and toxicity. Scientists are continuously researching to balance their utility with ecological mindfulness.
  • Research Applications: In the laboratory, hexadecylammonium chloride is used to modify surfaces and create functionalized materials. Researchers often explore its ability to assist in creating nanoscale devices and in the study of colloidal systems.

In conclusion, hexadecylammonium chloride showcases the intersection of everyday utility and scientific exploration, making it an important compound in both industrial and research settings.

Synonyms
Hexadecylammonium chloride
hexadecylazanium;chloride
1602-97-7
n-Hexadecylamine hydrochloride
1-Hexadecanamine, hydrochloride
5003FWN7LY
EINECS 216-499-5
UNII-5003FWN7LY
AI3-15079
SCHEMBL127069
NS00081336