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Hexamethylenediamine

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Identification
Molecular formula
C6H16N2
CAS number
124-09-4
IUPAC name
hexane-1,6-diamine
State
State

At room temperature, hexamethylenediamine is typically in a solid crystalline state, but it can also be encountered as a colorless liquid depending on environmental temperature.

Melting point (Celsius)
40.00
Melting point (Kelvin)
313.15
Boiling point (Celsius)
204.00
Boiling point (Kelvin)
477.15
General information
Molecular weight
116.21g/mol
Molar mass
116.2060g/mol
Density
0.8546g/cm3
Appearence

Hexamethylenediamine appears as a white crystalline solid or a colorless liquid. It has a distinctive amine odor reminiscent of ammonia. The compound can also exhibit moisture absorption, appearing damp.

Comment on solubility

Solubility of Hexane-1,6-diamine

Hexane-1,6-diamine, also known as 1,6-diaminohexane, exhibits intriguing solubility characteristics due to its molecular structure. This compound is a straight-chain aliphatic diamine with two amine groups that greatly influence its interactions with solvents.

  • Polar Solvents: Hexane-1,6-diamine demonstrates noticeable solubility in water due to the presence of the amine groups, which can form hydrogen bonds with water molecules.
  • Non-Polar Solvents: Conversely, its solubility in non-polar organic solvents such as hexane is much lower. This is a typical trend seen in amines, where the hydrophilic (water-loving) properties of the amine groups contrast with the hydrophobic (water-fearing) hydrocarbon chain.

In summary, while hexane-1,6-diamine is relatively soluble in polar solvents (like water), its solubility decreases significantly in non-polar solvents. Thus, its behavior exemplifies the principle of "like dissolves like" in chemistry.

Interesting facts

Hexane-1,6-diamine: An Insight into Its Significance

Hexane-1,6-diamine, commonly known as 1,6-diaminohexane, is a fascinating compound with a variety of applications in the field of chemistry and industry. Here are some compelling facts about this intriguing molecule:

  • Structure and Isomerism: Hexane-1,6-diamine features a straight-chain aliphatic structure with amine functional groups at both terminals. Its linear arrangement allows it to have specific interactions with other molecules, making it a key component in numerous chemical syntheses.
  • Uses in Polymer Chemistry: This compound is particularly significant in the production of polyamides. It serves as a crucial building block in the synthesis of nylon-6,6, which is widely used in textiles and engineering plastics.
  • Role in Biological Systems: Hexane-1,6-diamine derivatives have been studied for their biological activities. They can act as intermediates in the synthesis of various pharmaceuticals, highlighting the compound's relevance to medicinal chemistry.
  • Research Applications: The compound is frequently explored in research settings, particularly in studies related to surfactants and coatings. Its amine groups contribute to reactivity that can be exploited in creating new materials.
  • Safety Considerations: While hexane-1,6-diamine offers many advantages, it is essential to handle it with care. It can be irritating to the skin and eyes, necessitating proper safety protocols when working with this compound.

In the words of a prominent chemist, “A compound’s potential lies not just in its structure, but in the depth of possibilities it presents.” Hexane-1,6-diamine epitomizes this notion, proving that even simple molecules can lead to complex and valuable applications.

Overall, hexane-1,6-diamine is more than just a chain of carbon atoms with amino groups; it is a versatile compound that plays a crucial role in various industrial and scientific domains. Its broad applicability highlights the interconnectedness of chemistry with real-world applications.

Synonyms
1,6-Hexanediamine
Hexamethylenediamine
124-09-4
HEXANE-1,6-DIAMINE
HMDA
1,6-Hexylenediamine
HEXAMETHYLENE DIAMINE
1,6-Diamino-n-hexane
diaminohexane
Hexane, 1,6-diamino-
NCI-C61405
HEX-NH2
NSC 9257
CCRIS 6224
H2N(CH2)6NH2
HSDB 189
UNII-ZRA5J5B2QW
EINECS 204-679-6
BRN 1098307
DTXSID5024922
CHEBI:39618
AI3-37283
NSC-9257
HEXANEMETHYLENEDIAMINE-
DTXCID604922
EC 204-679-6
4-04-00-01320 (Beilstein Handbook Reference)
HMD(A)
204-679-6
1,6-hexanediamine (acgih)
1,6-Diaminohexane
1,6-Hexamethylenediamine
Hexylenediamine
MFCD00008243
ZRA5J5B2QW
CHEMBL303004
6-aminohexylamine
1,6-Diaminohexane-d12 dihydrochloride
HEXAMETHYLENE-1,6-13C2-DIAMINE
1,6-DIAMINO(HEXANE-2,2,5,5-D4)
284474-80-2
hexamethyldiamine
16D
CAS-124-09-4
UN1783
UN2280
1,6diaminohexane
1,6 diaminohexane
1.6-diaminohexane
1,6-diamino hexane
1,6-hexamethylene diamine
Hexamethylenediamine, solid
Hexamethylenediamine, 98%
WLN: Z6Z
Hexamethylene diamine, solid
NCIOpen2_002722
SCHEMBL15085
UN 1783 (Salt/Mix)
SCHEMBL7090279
1,6-HEXANEDIAMINE [MI]
NSC9257
HEXAMETHYLENE DIAMINE [HSDB]
Tox21_202088
Tox21_303123
BBL027705
BDBM50323740
STL281875
AKOS000118875
DB03260
FH16093
UN 2280
NCGC00091677-01
NCGC00091677-02
NCGC00257104-01
NCGC00259637-01
BP-21415
VS-08580
Hexamethylenediamine, technical grade, 70%
D0095
NS00001449
EN300-19313
G77311
AG-690/11351767
AG-690/11351768
Hexamethylenediamine, SAJ first grade, >=98.0%
Q424936
Hexamethylenediamine, solid [UN2280] [Corrosive]
Hexane-1,6-diamine 100 microg/mL in Acetonitrile
Z104473514
InChI=1/C6H16N2/c7-5-3-1-2-4-6-8/h1-8H
vegetable-oil, N,N'-hexanediylbis-Amides1,6-Hexandiamine, vegetable oil fatty acids diamide vegetable-oil, n,n'-hexanediylbis-amide Amides,vegetable-oil,N,N'-hexanediylbis- 1,6-Hexandiamine,vegetable oil fatty acids diamide