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Hexylparaben

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Identification
Molecular formula
C13H18O3
CAS number
108-68-9
IUPAC name
hexyl 4-hydroxybenzoate
State
State
Hexylparaben is typically a solid at room temperature. It is generally stable and does not readily vaporize.
Melting point (Celsius)
56.00
Melting point (Kelvin)
329.15
Boiling point (Celsius)
342.20
Boiling point (Kelvin)
615.35
General information
Molecular weight
222.28g/mol
Molar mass
222.2810g/mol
Density
1.0560g/cm3
Appearence

Hexylparaben appears as a white crystalline powder. It may also sometimes be found as a colorless solid.

Comment on solubility

Solubility of Hexyl 4-Hydroxybenzoate

Hexyl 4-hydroxybenzoate, a chemical compound often used in cosmetics and pharmaceuticals, exhibits interesting solubility characteristics:

  • Solvent Compatibility: It is generally soluble in organic solvents such as ethanol, ether, and chloroform.
  • Water Solubility: This compound has limited solubility in water, which can be attributed to its hydrophobic hexyl chain.
  • Temperature Dependence: The solubility may increase with temperature; as the temperature rises, the kinetic energy of the molecules enhances interactions with solvents.

The solubility profile of hexyl 4-hydroxybenzoate can often be summarized with the quote: "Like dissolves like." This means that hexyl 4-hydroxybenzoate, being a non-polar compound due to its long carbon chain, will interact better with non-polar or slightly polar solvents rather than polar solvents like water.

In practical applications, when formulating products with hexyl 4-hydroxybenzoate, it is essential to consider its solubility to ensure proper incorporation into different media, enhancing product efficacy and stability.

Interesting facts

Hexyl 4-Hydroxybenzoate: A Multifunctional Compound

Hexyl 4-hydroxybenzoate, commonly known as paraben, is a fascinating compound that falls under the category of esters and is widely used in various industries.

Key Uses and Applications

  • Cosmetics: One of the most popular applications of hexyl 4-hydroxybenzoate is in cosmetics, where it serves as a preservative. Its ability to inhibit the growth of harmful bacteria and mold makes it essential for extending shelf life in various beauty products.
  • Pharmaceuticals: Due to its antibacterial properties, it is also frequently used in pharmaceutical formulations to enhance product stability.
  • Food Industry: Though less common, it can be found in some food products, serving a similar preservative function.

Properties and Characteristics

This compound is characterized by:

  • Antimicrobial Activity: Hexyl 4-hydroxybenzoate exhibits strong antimicrobial activity, making it effective in preventing spoilage.
  • Low Toxicity: It has a low toxicity profile, which is particularly advantageous in cosmetic applications.
  • pH Stability: The stability of hexyl 4-hydroxybenzoate across a range of pH levels enhances its versatility in formulations.

Environmental and Health Considerations

Despite its vast applications, there are ongoing discussions regarding the potential health effects of parabens, including hexyl 4-hydroxybenzoate:

  • Some studies suggest a possible link between parabens and endocrine disruption, leading to cautious usage in cosmetics.
  • Regulatory agencies continue to evaluate its safety, making research in this area particularly dynamic.

In conclusion, hexyl 4-hydroxybenzoate exemplifies the duality of chemical compounds: while it offers substantial benefits in preservation and stability, its usage prompts essential discussions about health implications. As research evolves, staying informed about such compounds is crucial for both consumers and practitioners in the field.

Synonyms
Hexyl 4-hydroxybenzoate
1083-27-8
Hexylparaben
Hexyl p-hydroxybenzoate
Benzoic acid, 4-hydroxy-, hexyl ester
p-Hydroxybenzoic acid hexyl ester
Hexyl 4-hydroxybenzoat
p-Oxybenzoesaurehexylester
p-Oxybenzoesaeurehexylester
4-Hydroxybenzoesaeurehexylester
4-Hydroxybenzoic Acid Hexyl Ester
p-Oxybenzoesaurehexylester [German]
BRN 2723592
DTXSID1044514
BENZOIC ACID, p-HYDROXY-, HEXYL ESTER
14Y8G9635E
DTXCID9024514
Benzoic acid, 4-hydroxy-, hexyl ester (9CI)
679-688-5
4-hydroxybenzoic acid n-hexyl ester
n-hexyl 4-hydroxybenzoate
CAS-1083-27-8
n-Hexyl-4-hydroxybenzoate
UNII-14Y8G9635E
MFCD00016480
n-hexyl-p-hydroxybenzoate
Hexyl -4-Hydroxybenzoate
n-Hexyl p-hydroxy benzoate
SCHEMBL374758
CHEMBL2271366
Tox21_202266
Tox21_303422
AKOS016846151
FH70023
NCGC00249202-01
NCGC00257292-01
NCGC00259815-01
AS-44334
CS-0207336
H0213
A10845
AH-034/32462037
Q27251661
InChI=1/C13H18O3/c1-2-3-4-5-10-16-13(15)11-6-8-12(14)9-7-11/h6-9,14H,2-5,10H2,1H