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Foscarnet

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Identification
Molecular formula
C1H4O7P2
CAS number
63585-09-1
IUPAC name
[hydroxy-[[5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methoxy]phosphoryl] phosphono hydrogen phosphate
State
State

At room temperature, foscarnet is generally a solid. It is often supplied as a sodium salt, specifically foscarnet sodium, for pharmaceutical use.

Melting point (Celsius)
241.50
Melting point (Kelvin)
514.65
Boiling point (Celsius)
-123.15
Boiling point (Kelvin)
150.00
General information
Molecular weight
126.04g/mol
Molar mass
126.0420g/mol
Density
2.0054g/cm3
Appearence

Foscarnet typically appears as a white, crystalline powder. This compound is known for its high solubility in water, making it administrable in intravenous solutions, which are clear and colorless when prepared correctly.

Comment on solubility

Solubility Overview

The compound hydroxy-[[5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methoxy]phosphoryl] phosphono hydrogen phosphate, or C1H4O7P2, exhibits intriguing solubility characteristics that can be impacted by various factors.

Factors Influencing Solubility

Several aspects determine the solubility of this complex compound:

  • Polarity: The presence of hydroxyl (-OH) and phosphate groups can enhance its polar nature, often increasing solubility in polar solvents like water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules typically improves solubility in aqueous solutions.
  • Molecular Size: Larger molecular structures may hinder solubility due to steric hindrance, affecting how easily the compound interacts with solvent molecules.

General Solubility Behavior

While specific solubility data for this compound may not be readily available, we can make some educated assumptions:

  • It is likely to be more soluble in *polar solvents* compared to *non-polar solvents*.
  • Typically, compounds with similar functional groups exhibit increased solubility in water.
  • Due to the presence of multiple functional groups, solubility may also be influenced by pH and temperature changes.

In conclusion, understanding the solubility of C1H4O7P2 requires careful consideration of its chemical structure and the interactions it forms with different solvents. As stated, "solubility is a dance of forces between solute and solvent," highlighting the complexity of predicting solubility without empirical data.

Interesting facts

Interesting Facts about Hydroxy-[[5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methoxy]phosphoryl] Phosphono Hydrogen Phosphate

This compound is a fascinating example of the complexity that can arise in organic chemistry, particularly in the field of phosphorylated compounds. Recognized for its ability to play a significant role in biological systems, hydroxy-[[5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methoxy]phosphoryl] phosphono hydrogen phosphate exhibits a range of intriguing properties:

  • Biochemical Significance: Compounds of this nature are often involved in pivotal biochemical processes, such as metabolism and signal transduction.
  • Phosphate Groups: The presence of phosphate groups in its structure makes it an important player in nucleic acid chemistry, influencing DNA and RNA functions.
  • Potential Applications: This compound may have applications in drug design and development, especially as potential therapeutic agents targeting specific biological pathways.
  • Structural Diversity: Its complex structure, which includes a pyrimidine derivative, showcases the immense diversity found in chemical compounds and their interactions.
  • Research Interest: Scientists are continually exploring the reactivity and stability of phosphonates, like this compound, due to their interesting physicochemical properties.

In essence, hydroxy-[[5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methoxy]phosphoryl] phosphono hydrogen phosphate represents a thrilling intersection of organic chemistry and biochemical applications. As researchers delve deeper into its functionalities, more exciting discoveries are likely to surface, further expanding our understanding of this intricate class of compounds.

Synonyms
[hydroxy-[[5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methoxy]phosphoryl] phosphono hydrogen phosphate