Skip to main content

Berberine

ADVERTISEMENT
Identification
Molecular formula
C20H18NO4
CAS number
2086-83-1
IUPAC name
hydroxy-dimethyl-[2-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyloxy)ethyl]ammonium
State
State

At room temperature, berberine is typically a solid. It is generally available in powder form, although it can also be processed into capsules or tablets. Its solid-state makes it relatively stable for storage and handling as a supplement or research compound.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.00
Boiling point (Celsius)
454.00
Boiling point (Kelvin)
727.00
General information
Molecular weight
336.36g/mol
Molar mass
336.3610g/mol
Density
1.3000g/cm3
Appearence

Berberine is a yellow crystalline alkaloid. It is often found as a yellow or yellow-brown powder. Berberine can also appear in the form of bright yellow needles or crystals. It is intensely yellow in color and is used for dyeing fabrics and as a chemical indicator.

Comment on solubility

Solubility of Hydroxy-dimethyl-[2-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyloxy)ethyl]ammonium

The solubility of hydroxy-dimethyl-[2-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyloxy)ethyl]ammonium can be complex due to its intricate molecular structure.

Key Factors Influencing Solubility:

  • Polar and Non-Polar Characteristics: The presence of hydroxyl (–OH) groups may enhance solubility in polar solvents such as water, while the hydrophobic tetracyclic portions of the compound may limit its solubility.
  • Temperature: Solubility often increases with temperature; thus, heating may improve the dissolution of this compound in appropriate solvents.
  • pH Levels: The ammonium group may change its charge depending on the pH of the solution, affecting solubility in aqueous environments.

In general, compounds with large and complex hydrocarbon frameworks tend to exhibit lower solubility in polar solvents. It is often observed that:

  1. Hydrophobic interactions become significant, leading to precipitation in aqueous solutions.
  2. Solubility can vary greatly with the choice of solvent.

In conclusion, the solubility of hydroxy-dimethyl-[2-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyloxy)ethyl]ammonium is likely to be limited, especially in non-polar environments. Experimentation in various solvent systems is essential to determine its practical solubility.

Interesting facts

Interesting Facts about Hydroxy-dimethyl-[2-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyloxy)ethyl]ammonium

This compound is a fascinating example of organic chemistry that combines unique structural features with potential applications in various fields. Let's delve into some intriguing aspects:

  • Complex Structure: The compound exhibits a complicated structure with multiple cyclohexadecane rings, showcasing the intricate nature of organic synthesis. The tetracyclic arrangement is indicative of its potential biological activity.
  • Dual Functionality: The presence of both hydroxy and ammonium groups allows this compound to function effectively in both aqueous and organic environments, making it versatile for applications in drug design and delivery systems.
  • Potential Anticancer Activity: Research indicates that compounds with such intricate polycyclic frameworks may exhibit anticancer properties, inviting ongoing studies into their pharmacological applications.
  • Self-Assembly: The unique geometric configuration enables the possibility of self-assembly into organized structures, which is a key focus in materials science and nanotechnology.
  • Applications in Surfactants: Surfactant properties may emerge from this compound’s amphiphilic nature, potentially finding uses in emulsifiers and dispersants.
  • Studying Reactivity: The nitrogen atom in the ammonium group alters the compound's reactivity, paving the way for various substitution reactions that could lead to the synthesis of new derivatives.

In summary, hydroxy-dimethyl-[2-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyloxy)ethyl]ammonium is not just a mere chemical compound; it embodies the potential for revolutionary advancements in medicinal chemistry and materials science. As chemists explore its properties further, we may uncover new pathways for innovation and applications.