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Indan-5-ol

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Identification
Molecular formula
C9H10O
CAS number
19459-47-5
IUPAC name
indan-5-ol
State
State
At room temperature, indan-5-ol is typically found as a solid, often in the form of crystalline structures.
Melting point (Celsius)
37.00
Melting point (Kelvin)
310.15
Boiling point (Celsius)
249.00
Boiling point (Kelvin)
522.15
General information
Molecular weight
134.18g/mol
Molar mass
134.1790g/mol
Density
1.1396g/cm3
Appearence

Indan-5-ol is typically a colorless to pale yellow crystalline solid. It may appear as transparent crystals or a powder, depending on its form. This compound may also be slightly viscous as a liquid.

Comment on solubility

Solubility of Indan-5-ol

Indan-5-ol, with the chemical formula C9H10O, exhibits specific solubility characteristics that are noteworthy.

Key points about the solubility of Indan-5-ol:

  • Indan-5-ol is generally considered to be moderately soluble in organic solvents.
  • Its solubility in water is limited due to its hydrophobic indan structure, which hinders strong interactions with water molecules.
  • However, it can dissolve in polar organic solvents such as alcohols and ethers, which can form hydrogen bonds with the hydroxyl (-OH) group.

As a compound, its solubility can be affected by several factors, including:

  1. Temperature: Increased temperature generally enhances solubility in organic solvents.
  2. pH levels: The presence of acidic or basic conditions may influence the ionization of the hydroxyl group, impacting solubility.
  3. Molecular interactions: The ability to engage in hydrogen bonding with solvents plays a critical role in solubility.

In summary, while Indan-5-ol has limited solubility in water, its compatibility with various organic solvents expands its utility in chemical applications. Understanding these solubility parameters is essential for effective use in synthesis and formulation.

Interesting facts

Interesting Facts about Indan-5-ol

Indan-5-ol, a fascinating compound belonging to the indan family, has captured the attention of chemists and researchers alike due to its unique structural and chemical properties. Here are some intriguing aspects of this compound:

  • Structural Features: Indan-5-ol is characterized by its fused-ring structure, which involves a bicyclic framework. This structure gives rise to unique chemical reactivity and makes it a valuable scaffold in organic synthesis.
  • Applications in Synthesis: Its derivatives play significant roles in the development of pharmaceuticals. For example, compounds based on indan-5-ol have been explored as potential anti-inflammatory agents and as intermediates in various chemical syntheses.
  • Natural Occurrence: Indan-based compounds are often found in nature, either as natural products or as precursors to biologically active molecules. This adds an element of ecological relevance to the study of indan-5-ol.
  • Research Insights: Scholars have reported that the hydroxyl group at position 5 enhances the compound's nucleophilicity, which can be exploited in various chemical reactions, including nucleophilic substitutions.
  • Chiral Centers: Some derivatives of indan-5-ol possess chiral centers, which presents opportunities for exploring stereochemistry in synthesis and the development of enantiomerically pure compounds, essential in medicinal chemistry.

As the field of organic chemistry evolves, compounds like indan-5-ol continue to inspire new research avenues and inventive applications. The ongoing studies aim not only to unlock further potential in traditional applications but also to explore its possibilities in advanced materials and other cutting-edge domains.

In the words of a prominent chemist, "The beauty of organic compounds lies in their complexity and the endless possibilities they offer for innovation." Indan-5-ol epitomizes this sentiment, inviting further exploration into its chemical versatility.

Synonyms
5-INDANOL
1470-94-6
2,3-dihydro-1H-inden-5-ol
Indan-5-ol
5-Hydroxyindan
5-Hydroxyhydrindene
1H-Inden-5-ol, 2,3-dihydro-
5-Hydroxyindane
NSC 9775
EINECS 216-006-3
BRN 1936314
DTXSID0051732
CHEBI:59311
AI3-39160
9Z94H6F15T
NSC-9775
2,3-dihydroinden-5-ol
DTXCID6030287
4-06-00-03829 (Beilstein Handbook Reference)
5Hydroxyindan
Indan5ol
5Hydroxyhydrindene
1HInden5ol, 2,3dihydro
216-006-3
MFCD00003802
Indanol-5
UNII-9Z94H6F15T
NSC9775
5-Indanol, 99%
WLN: L56T&J GQ
1H-Inden-5-ol,3-dihydro-
SCHEMBL281714
CHEMBL3218378
Tox21_303902
AKOS005207221
AC-4785
FI42892
NCGC00357155-01
AS-44253
SY049594
CAS-1470-94-6
DB-042868
DB-063694
CS-0214750
H0251
NS00003561
EN300-19024
A10309
Q27126618
InChI=1/C9H10O/c10-9-5-4-7-2-1-3-8(7)6-9/h4-6,10H,1-3H