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Indolin-6-amine

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Identification
Molecular formula
C8H10N2
CAS number
24994-27-2
IUPAC name
indolin-6-amine
State
State

Indolin-6-amine is a solid at room temperature. It has a stable structure and does not vaporize easily.

Melting point (Celsius)
104.00
Melting point (Kelvin)
377.15
Boiling point (Celsius)
399.50
Boiling point (Kelvin)
672.65
General information
Molecular weight
134.19g/mol
Molar mass
134.1850g/mol
Density
1.1800g/cm3
Appearence

Indolin-6-amine appears as a solid compound and typically forms crystalline structures. The color of these crystals can vary, but they are often white to off-white. The crystalline form is due to the orderly repeating pattern of its molecular structure.

Comment on solubility

Solubility of Indolin-6-amine

Indolin-6-amine, a member of the indole class of chemical compounds, presents unique solubility characteristics that are influenced by its structure. Here are some key points to consider:

  • Solubility in Water: Indolin-6-amine has limited solubility in water, primarily due to its hydrophobic aromatic ring which resists interaction with water molecules.
  • Polar Solvents: It shows improved solubility in polar organic solvents such as ethanol and methanol, making these solvents effective for dissolution.
  • Non-Polar Solvents: The compound is easily soluble in non-polar solvents like dichloromethane or chloroform, highlighting its lipophilic nature.

In conclusion, the solubility of indolin-6-amine can be characterized as follows:

  1. Moderately soluble in polar organic solvents.
  2. Low solubility in water.
  3. Highly soluble in non-polar solvents.

These solubility traits make indolin-6-amine a versatile compound in synthetic applications while also influencing its behavior in biological systems.

Interesting facts

Interesting Facts about Indolin-6-Amine

Indolin-6-amine is a fascinating compound that plays an important role in both synthetic organic chemistry and medicinal chemistry. Here are some key points to consider:

  • Diverse Applications: This compound is often used as a building block in the synthesis of various pharmaceutical agents. Its unique structure allows for the development of potential drugs targeting different diseases.
  • Biological Interest: Indolin-6-amine derivatives have shown potential as inhibitors in several biological pathways, making them subjects of interest for drug discovery and development.
  • Structural Features: The indole ring system and the amino group in its structure enable the compound to participate in various chemical reactions, including nucleophilic substitutions and coupling reactions.
  • Chemical Reactivity: Due to the presence of the amino group, Indolin-6-amine can form hydrogen bonds, enhancing its reactivity and solubility in various organic solvents.
  • Research Studies: Numerous studies have explored the electronic properties and interactions of this compound, with findings suggesting its potential use in the development of organic semiconductors and materials.

In summary, Indolin-6-amine is a compound that not only captivates chemists with its reactivity but also inspires research and innovation in the field of pharmaceuticals and materials science. As one researcher noted, "The versatility of indoline compounds holds great promise for future therapeutic agents."

Understanding its properties and reactivity can lead to breakthrough applications in medicine and material science.

Synonyms
INDOLIN-6-AMINE
15918-79-3
2,3-dihydro-1H-indol-6-amine
6-Aminoindoline
1H-Indol-6-amine, 2,3-dihydro-
6-Indolinamine
MFCD11590551
6-Aminoindolin
SCHEMBL94057
ALBB-014225
2,3-Dihydro-1H-indol-6-ylamine #
AKOS005174369
SB64372
LS-04472
SY409540
DB-064269
CS-0105947
G73003
EN300-2993945
F369953