Skip to main content

Phthalic anhydride

ADVERTISEMENT
Identification
Molecular formula
C8H4O3
CAS number
85-44-9
IUPAC name
isobenzofuran-1,3-dione
State
State

Phthalic anhydride is typically in a solid state at room temperature.

Melting point (Celsius)
131.00
Melting point (Kelvin)
404.15
Boiling point (Celsius)
295.00
Boiling point (Kelvin)
568.15
General information
Molecular weight
148.12g/mol
Molar mass
148.1160g/mol
Density
1.5270g/cm3
Appearence

Phthalic anhydride is a white crystalline solid. It often appears as large, colorless crystals or as a white powder. The compound has a sharp, acrid odor often associated with its volatile nature when heated.

Comment on solubility

Solubility of Isobenzofuran-1,3-dione

Isobenzofuran-1,3-dione, also known as phthalic anhydride, exhibits intriguing solubility characteristics that are essential for its applications in various chemical processes. When considering its solubility behavior, a few key points emerge:

  • Solvent Compatibility: Isobenzofuran-1,3-dione is generally soluble in a range of organic solvents, including ethyl acetate, acetone, and benzene.
  • Poor Water Solubility: This compound has a notably low solubility in water. This is attributed to its non-polar nature and the presence of aromatic structures that do not favor interactions with polar solvents.
  • Temperature Dependency: The solubility of isobenzofuran-1,3-dione can increase with rising temperatures, which is common for many organic compounds. As temperature increases, molecular movement enhances, facilitating dissolution.
  • Practical Applications: Due to its solubility profile, isobenzofuran-1,3-dione is often utilized in resin production and chemical synthesis where organic solvents are employed.

This solubility behavior highlights the importance of selecting the right solvent during chemical reactions involving isobenzofuran-1,3-dione, ensuring efficient usage and maximizing reactivity in synthesis.

Interesting facts

Interesting Facts about Isobenzofuran-1,3-dione

Isobenzofuran-1,3-dione, often referred to as a diketone compound, is a member of the larger class of compounds known as benzofurans. This compound is notable for several reasons:

  • Chemical Structure: The structure consists of a bicyclic framework, combining both a benzene ring and a furan ring. This unique arrangement contributes to its intriguing chemical properties.
  • Versatile Reactions: Isobenzofuran-1,3-dione is capable of undergoing various chemical reactions. These include nucleophilic addition, electrophilic substitution, and cycloaddition reactions, showcasing a rich chemistry that intrigues researchers.
  • Biological Significance: Some derivatives of isobenzofuran-1,3-dione have been studied for potential biological activities, including anti-inflammatory and antimicrobial properties, making it a point of interest in medicinal chemistry.
  • Applications in Organic Synthesis: Due to its reactivity, it is often used as an intermediate in the synthesis of other organic compounds, particularly in the development of various pharmaceuticals and agrochemicals.
  • Environmental Impact: The study of such compounds extends to understanding environmental chemistry, as materials containing isobenzofuran derivatives may enter ecosystems through various pathways, necessitating further investigation into their environmental fate.

In summary, isobenzofuran-1,3-dione is not just a chemical entity, but a compound that bridges numerous fields, from synthetic organic chemistry to potential pharmaceutical developments. As researchers and students delve deeper into its properties, they continue to uncover the complexities and possibilities that this fascinating compound has to offer.

Synonyms
PHTHALIC ANHYDRIDE
85-44-9
Isobenzofuran-1,3-dione
1,3-Isobenzofurandione
2-Benzofuran-1,3-dione
1,3-Dioxophthalan
1,3-Phthalandione
Phthalsaeureanhydrid
o-Phthalic acid anhydride
Phthalic acid anhydride
Phthalandione
Retarder esen
Retarder AK
Retarder PD
Vulkalent B/C
Anidride ftalica
ESEN
Ftalowy bezwodnik
Ftaalzuuranhydride
Anhydride phtalique
Ftalanhydrid
1,2-Benzenedicarboxylic anhydride
1,2-Benzenedicarboxylic acid anhydride
Vulkalent B
Wiltrol P
Phthalanhydride
RCRA waste number U190
NCI-C03601
TGL 6525
Anhydrid kyseliny ftalove
Sconoc 7
Araldite HT 901
ortho-phthalic acid anhydride
CCRIS 519
NSC 10431
1,3-dihydro-2-benzofuran-1,3-dione
CHEBI:36605
HSDB 4012
Isobenzofuran, 1,3-dihydro-1,3-dioxo-
phtalic anhydride
UNII-UVL263I5BJ
EINECS 201-607-5
UVL263I5BJ
MFCD00005918
DTXSID2021159
AI3-04869
Ht 901
NSC-10431
DTXCID401159
EC 201-607-5
Ftalanhydrid [Czech]
Ftaalzuuranhydride [Dutch]
Anidride ftalica [Italian]
Ftalowy bezwodnik [Polish]
Retarder B-C
Anhydride phtalique [French]
Phthalsaeureanhydrid [German]
Anhydrid kyseliny ftalove [Czech]
UN2214
RCRA waste no. U190
Phthalic anhydride (molten)
Phthalic Anhydride (May Contain Up To 15% Of Phthalic Acid)
pthalic anhydride
Retarder PX
o-phthalic anhydride
1,3-dihydro-1,3-dioxoisobenzofuran
PhthalicAcidAnhydride-d4
isobenzofurane-1,3-dione
SCHEMBL220
Epitope ID:112744
WLN: T56 BVOVJ
1,3-DIOXOPHTHALANE
1,3-DIOXONAPHTHALAN
2-Benzofuran-1,3-dione #
UN 2214 (Salt/Mix)
Phthalic anhydride treated BSA
Phthalic anhydride treated HSA
Phthalic anhydride, ACS grade
PHTHALIC ANHYDRIDE [MI]
CHEMBL1371297
PHTHALIC ANHYDRIDE [HSDB]
Phthalic anhydride treated gelatin
Phthalic anhydride treated casein I
NSC10431
Phthalic anhydride treated casein II
Tox21_200142
1,3-dihydroisobenzofuran-1,3-dione
Isobenzofuran,3-dihydro-1,3-dioxo-
MSK002114
STL194302
AKOS000121309
FP33075
CAS-85-44-9
NCGC00091060-01
NCGC00091060-02
NCGC00257696-01
BP-30002
Phthalic anhydride, ACS reagent, >=99%
PS-10628
Phthalic anhydride, for synthesis, 99.0%
Phthalic anhydride, ReagentPlus(R), 99%
1ST002114
1,3-DIHYDRO-1,3-DIOXOISOBENZOFURANE
NS00004500
P1614
Phthalic anhydride, purum, >=97.0% (NT)
EN300-18017
P60058
Phthalic anhydride with >0.05% maleic anhydride
Phthalic anhydride, SAJ first grade, >=99.0%
A841333
Q410882
F1908-0105
InChI=1/C8H4O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h1-4
Phthalic anhydride with >0.05% maleic anhydride [UN2214] [Corrosive]
Phthalic anhydride, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=99%
201-607-5