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Isobutyl salicylate

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Identification
Molecular formula
C11H14O3
CAS number
87-20-7
IUPAC name
isobutyl 2-hydroxybenzoate
State
State

At room temperature, isobutyl salicylate is a liquid. It is commonly used in liquid form in various applications, including fragrances and flavors.

Melting point (Celsius)
-43.00
Melting point (Kelvin)
230.15
Boiling point (Celsius)
108.00
Boiling point (Kelvin)
381.15
General information
Molecular weight
194.24g/mol
Molar mass
194.2370g/mol
Density
1.0800g/cm3
Appearence

Isobutyl salicylate is a colorless to pale yellow liquid. It has a pleasant, floral fragrance, reminiscent of orchids and bananas. It is often used in perfumery and flavoring for its aromatic properties.

Comment on solubility

Solubility of Isobutyl 2-Hydroxybenzoate

Isobutyl 2-hydroxybenzoate, with the chemical formula C11H14O3, demonstrates distinct solubility characteristics that are important for its applications. Here’s what to note:

  • Solvent Compatibility: This compound exhibits good solubility in organic solvents such as ethanol, methanol, and acetone, which is typical for many esters and aromatic compounds.
  • Aqueous Solubility: Isobutyl 2-hydroxybenzoate has low solubility in water. This behavior can be attributed to its hydrophobic isobutyl group and the overall nonpolar nature of the molecule.
  • Temperature Effects: Similarly to many organic compounds, solubility can be affected by temperature; a higher temperature generally increases solubility in organic solvents due to enhanced molecular interactions.

In summary, while isobutyl 2-hydroxybenzoate is more soluble in non-polar and moderately polar solvents, its limited solubility in water emphasizes the need for specific solvents during practical applications. This property is crucial, particularly in formulations involving pharmaceuticals and cosmetics where solvent choice can significantly influence the efficacy and stability of the final product.

Interesting facts

Interesting Facts about Isobutyl 2-hydroxybenzoate

Isobutyl 2-hydroxybenzoate, also known as isoamyl salicylate, is an intriguing compound that plays a significant role in various industries, particularly in cosmetics and personal care products. Here are some fascinating aspects of this compound:

  • Modern Applications: Isobutyl 2-hydroxybenzoate is used primarily as a fragrance ingredient. It offers a pleasant floral scent and is often incorporated into perfumes, lotions, and other cosmetic formulations.
  • Preservative Qualities: Beyond its aromatic properties, this compound exhibits some antimicrobial activity, which makes it useful in preserving the integrity of products against microbial growth.
  • Skin Penetration Enhancement: Research has shown that isobutyl 2-hydroxybenzoate can act as a penetration enhancer in topical formulations, allowing other active ingredients to penetrate the skin more effectively.
  • Regulatory Status: The safety of this compound has been evaluated by multiple regulatory agencies, and it is generally regarded as safe when used in appropriate concentrations in cosmetic applications.
  • Natural vs Synthetic: While it can be synthesized, similar compounds can also be derived from natural sources, which appeals to the growing trend towards natural and organic products in the cosmetic industry.

In the words of a chemist, "Understanding the multifaceted utility of compounds like isobutyl 2-hydroxybenzoate not only broadens our scientific horizons but also enhances our everyday lives." This compound’s versatile applications reflect its importance in both industrial and consumer contexts, making it a valuable topic of study for students and professionals alike.

Synonyms
Isobutyl salicylate
87-19-4
Isobutyl 2-hydroxybenzoate
2-Methylpropyl 2-hydroxybenzoate
Isobutyl o-hydroxybenzoate
2-Isobutoxycarbonylphenol
Benzoic acid, 2-hydroxy-, 2-methylpropyl ester
2-Methylpropyl o-hydroxybenzoate
SALICYLIC ACID, ISOBUTYL ESTER
Orchindone
2-Methyl-1-propyl salicylate
FEMA No. 2213
2-Methylpropyl salicylate
EINECS 201-729-9
NSC 62140
Salicylic Acid Isobutyl Ester
iso-butyl salicylate
UNII-S122C080GX
BRN 2615955
DTXSID3047186
AI3-24370
S122C080GX
NSC-62140
DTXCID1027186
ISOBUTYL SALICYLATE [FCC]
ISOBUTYL SALICYLATE [FHFI]
3-10-00-00121 (Beilstein Handbook Reference)
2-Hydroxybenzoic Acid Isobutyl Ester
MFCD00020035
SCHEMBL39110
WLN: QR BVO1Y1&1
CHEMBL2260712
FEMA 2213
CHEBI:173947
NSC62140
Isobutyl salicylate, >=98%, FCC
Tox21_302515
AKOS015837517
CAS-87-19-4
NCGC00256854-01
BS-42299
NS00012691
S0013
Q2214311
F0001-2160
201-729-9