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Isobutylparaben

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Identification
Molecular formula
C11H14O3
CAS number
4247-02-3
IUPAC name
isobutyl 4-hydroxybenzoate
State
State

At room temperature, isobutylparaben exists as a solid.

Melting point (Celsius)
76.00
Melting point (Kelvin)
349.15
Boiling point (Celsius)
266.40
Boiling point (Kelvin)
539.55
General information
Molecular weight
194.23g/mol
Molar mass
194.2290g/mol
Density
1.0840g/cm3
Appearence

Isobutylparaben is typically a white crystalline powder. It is often found in the form of needles or small crystalline fragments.

Comment on solubility

Solubility of Isobutyl 4-Hydroxybenzoate

Isobutyl 4-hydroxybenzoate, a chemical compound often used as a preservative, showcases varying solubility characteristics that are essential to its applications. The solubility of a compound is influenced by factors such as its molecular structure, polarity, and the temperature of the solvent. Here are some key points on its solubility:

  • Solvent Properties: Isobutyl 4-hydroxybenzoate is generally more soluble in organic solvents than in water. Common organic solvents include ethanol and chloroform.
  • Temperature Dependence: Like many organic compounds, its solubility can increase with temperature. Warm solvents can often dissolve more of the compound than cold solvents.
  • Polarity: The presence of the hydroxyl group (–OH) contributes to some degree of polarity, yet the isobutyl group’s hydrophobic characteristics mean it overall exhibits limited solubility in polar solvents such as water.

To summarize, isobutyl 4-hydroxybenzoate’s solubility is strongly tied to its organic nature, showcasing greater compatibility with non-polar to slightly polar solvents. This property plays a crucial role in its effectiveness as a preservative in various formulations.

Interesting facts

Interesting Facts About Isobutyl 4-Hydroxybenzoate

Isobutyl 4-hydroxybenzoate, commonly known as *isobutylparaben*, is a fascinating compound widely utilized in the cosmetic and pharmaceutical industries. This compound belongs to the family of parabens, which are esters of p-hydroxybenzoic acid, and they have garnered significant attention for their effectiveness as preservatives.

Key Features of Isobutyl 4-Hydroxybenzoate:

  • Preservative Properties: Isobutylparaben is known for its ability to inhibit the growth of harmful bacteria and fungi, thereby ensuring the longevity and safety of various products.
  • Cosmetic Usage: Found in a wide range of cosmetics and personal care items, such as lotions, shampoos, and makeup, it helps maintain product integrity over time.
  • Safety and Controversy: Despite its widespread use, parabens, including isobutylparaben, have faced scrutiny regarding their potential endocrine-disrupting effects, leading to ongoing research and debates in the scientific community.
  • Interchangeability: Isobutylparaben can often be replaced by other types of parabens, such as *propylparaben* or *ethylparaben*, allowing formulators flexibility based on product requirements.

As Dr. X stated, “Preservatives play a crucial role in product formulation, and understanding their mechanisms aids in the development of safer alternatives.” This quote underscores the importance of ongoing research into the functionality and safety of compounds like isobutyl 4-hydroxybenzoate.

Applications Beyond Cosmetics

Interestingly, isobutyl 4-hydroxybenzoate isn't confined solely to cosmetic applications. It also finds utility in:

  • Pharmaceutical formulations where preservation is equally important.
  • Food products, although its use in edibles has specific regulatory scrutiny.
  • Industrial products, particularly in formulations that require a longer shelf life.

Overall, isobutyl 4-hydroxybenzoate serves as a prime example of the complex interplay between efficacy, safety, and regulatory standards, illustrating the ongoing evolution of chemical compounds in consumer products.

Synonyms
Isobutyl 4-hydroxybenzoate
Isobutylparaben
4247-02-3
isobutyl paraben
Isobutyl p-hydroxybenzoate
2-Methylpropyl 4-hydroxybenzoate
Isobutyl-4-hydroxybenzoate
Isobutyl parahydroxybenzoate
Benzoic acid, 4-hydroxy-, 2-methylpropyl ester
4-Hydroxybenzoic Acid Isobutyl Ester
BENZOIC ACID, p-HYDROXY-, ISOBUTYL ESTER
p-Oxybenzoesaureisobutylester
0QQJ25X58G
DTXSID4020749
4-Hydroxybenzoic acid-isobutyl ester
2-Methylpropyl 4-Hydroxybenzoate (Isobutyl Parahydroxybenzoate)
4-Hydroxybenzoic acid-isobutyl ester 1000 microg/mL in Acetonitrile
isobutyl-p-hydroxybenzoate
CCRIS 2463
EINECS 224-208-8
p-Hydroxybenzoic acid isobutyl ester
MFCD00020167
4-hydroxybenzoic acid iso-butyl ester
p-Oxybenzoesaureisobutylester [German]
BRN 2642305
4-Hydroxybenzoic acid, 2-methylpropyl ester
ChemDiv2_000057
Isobutylparaben (Standard)
UNII-0QQJ25X58G
SCHEMBL34633
Methylpropyl p-hydroxybenzoate
BIDD:ER0110
DTXCID20749
CHEMBL3182006
CHEBI:178256
Isobutyl 4-hydroxybenzoate, 97%
HMS1369C13
Butyl parahydroxybenzoate impurity E
HY-W015026R
QYB46035
Tox21_200501
STL067196
ISOBUTYL PARA HYDROXY BENZOATE
p-Hydroxybenzoic acid iso-butyl ester
p-Hydroxybenzoic acid sec-butyl ester
AKOS000319531
CS-W015742
FI70451
HY-W015026
NCGC00248662-01
NCGC00258055-01
AC-34543
AS-15247
DA-54401
CAS-4247-02-3
DB-070303
EU-0033430
H0493
I0816
NS00007256
C20342
3-10-00-00308 (Beilstein Handbook Reference)
SR-01000389342
SR-01000389342-1
Q27237117
Butyl parahydroxybenzoate impurity E, European Pharmacopoeia (EP) Reference Standard
2-Methylpropyl 4-Hydroxybenzoate; Butyl Parahydroxybenzoate Imp. E (EP); Isobutyl Parahydroxybenzoate; Butyl Parahydroxybenzoate Impurity E