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Isoindolin-1-one

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Identification
Molecular formula
C8H7NO
CAS number
496-26-4
IUPAC name
isoindolin-1-one
State
State

Isoindolin-1-one is found in a solid state at room temperature, typically existing as a crystalline powder or solid lump.

Melting point (Celsius)
121.00
Melting point (Kelvin)
394.15
Boiling point (Celsius)
358.00
Boiling point (Kelvin)
631.15
General information
Molecular weight
133.15g/mol
Molar mass
133.1470g/mol
Density
1.2683g/cm3
Appearence

Isoindolin-1-one generally appears as a white or light yellow crystalline powder. This compound is typically found in a solid state with a characteristic appearance that indicates purity and crystallinity.

Comment on solubility

Solubility of Isoindolin-1-one

Isoindolin-1-one, with the chemical formula C8H7NO, exhibits intriguing solubility characteristics that can be influenced by various factors. This compound is typically considered moderately soluble in organic solvents, particularly in those like ethanol and acetone. However, its solubility in water is limited.

Here are some key points regarding the solubility of isoindolin-1-one:

  • Solvent Dependent: The solubility can vary with the choice of solvent. Polar solvents generally improve solubility compared to non-polar solvents.
  • Temperature Influence: Increasing temperature often enhances solubility, making it easier to dissolve in the selected solvent.
  • pH Levels: The pH of the solution can impact the solubility, particularly if the compound ionizes under certain conditions.

While isoindolin-1-one's limited solubility in water could imply challenges for aqueous applications, its compatibility with organic solvents opens avenues for use in the appropriate formulations. As noted, understanding the characteristics of the solvent is crucial for effectively utilizing this compound in various chemical processes.

Interesting facts

Interesting Facts About Isoindolin-1-one

Isoindolin-1-one is a fascinating compound that has garnered attention both for its structural uniqueness and its versatility in various fields. Here are some captivating insights:

  • Structural Signature: Isoindolin-1-one exhibits a distinctive bicyclic structure that combines elements of both isoindole and lactam functionalities. This unique configuration not only contributes to its chemical properties but also influences its reactivity patterns.
  • Biological Relevance: This compound is known for its potential biological activities. Researchers have identified isoindolin-1-one derivatives as promising candidates for pharmacological studies, particularly in areas such as antitumor and antimicrobial research. Its derivatives have shown noteworthy activity against various cell lines.
  • Synthetic Versatility: The synthesis of isoindolin-1-one can be achieved through various methods, including cyclization reactions and rearrangement processes. Its synthetic flexibility allows chemists to explore a diverse range of functionalized derivatives, broadening the scope of its applications.
  • Applications in Materials Science: Beyond its medicinal potential, isoindolin-1-one has been investigated for its use in materials science, particularly in the development of organic semiconductors and light-emitting diodes (LEDs). Its electronic properties make it a candidate for innovative applications in the field of nanotechnology.
  • Cultural Significance: As a compound of interest in various scientific disciplines, isoindolin-1-one also finds relevance in academic circles. Its study often leads to collaborative research that bridges chemistry, biology, and materials science, fostering interdisciplinary knowledge and innovations.

In conclusion, isoindolin-1-one is not just a compound of chemical curiosity but also a beacon of interdisciplinary research potential, with implications ranging from pharmacology to advanced materials. Its study continues to inspire scientists and students alike, making it a significant subject of interest in contemporary chemistry.

Synonyms
480-91-1
Phthalimidine
1-Isoindolinone
isoindolinone
1H-Isoindol-1-one, 2,3-dihydro-
41DB5814AL
NSC-3689
3,4-BENZOPYRROLIDONE
NSC 3689
DTXCID70122389
806-895-1
1h-isoindole-1,3(2h)-dione, 4,5-dihydro-
dtxsid10199898
isoindolin-1-one
2,3-DIHYDRO-1H-ISOINDOL-1-ONE
2,3-dihydroisoindol-1-one
MFCD03085939
1-oxo-isoindoline
2,3-Dihydro-isoindol-1-one
CHEBI:74235
dihydro-isoindol-1-one
CHEMBL79350
2,3-dihydro-3-oxo-1H-isoindole
UNII-41DB5814AL
NSC3689
1H-Isoindol-1-one,2,3-dihydro-
1-Isoindolinone #
Benzo(3,4)pyrrolidone-2
1-Isoindolinone, AldrichCPR
2,3-dihydroisoindole-1-one
SCHEMBL14896
SCHEMBL1144058
SCHEMBL15580117
DTXSID30197391
ALBB-012842
BDBM50143902
SC1218
STK628505
AKOS005173935
AB13096
CS-W004767
HY-W004767
SS-6041
AC-25604
SY020116
DB-070912
I1064
EN300-35925
Q27144540
Z362519344