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Isopropyl 2-(3-chloroanilino)-2-oxoacetate

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Identification
Molecular formula
C11H12ClNO3
CAS number
38364-26-0
IUPAC name
isopropyl 2-(3-chloroanilino)-2-oxo-acetate
State
State

At room temperature, Isopropyl 2-(3-chloroanilino)-2-oxoacetate is a solid. It can exist in a stable crystalline form and is typically handled as a powder or granule.

Melting point (Celsius)
76.00
Melting point (Kelvin)
349.20
Boiling point (Celsius)
344.30
Boiling point (Kelvin)
617.50
General information
Molecular weight
241.68g/mol
Molar mass
241.6760g/mol
Density
1.2761g/cm3
Appearence

Isopropyl 2-(3-chloroanilino)-2-oxoacetate appears as a crystalline solid. The coloration may vary depending on the purity and specific form, but it typically presents as a white to off-white powder.

Comment on solubility

Solubility of Isopropyl 2-(3-chloroanilino)-2-oxo-acetate

The solubility of isopropyl 2-(3-chloroanilino)-2-oxo-acetate can be influenced by several factors, making its behavior in solvents quite interesting:

  • Polar vs. Nonpolar Solvents: This compound, containing both polar and nonpolar functional groups, may possess solubility in solvents of varying polarity. For example, it could dissolve well in organic solvents like methanol or ethyl acetate.
  • Temperature Influence: Generally, an increase in temperature can enhance solubility for organic compounds; hence, heating the solvent may improve the dissolution of isopropyl 2-(3-chloroanilino)-2-oxo-acetate.
  • pH Sensitivity: The presence of the aniline moiety means that changes in pH could alter the ionization state of the compound, potentially impacting its solubility in aqueous solutions.

In summary, while the definitive solubility of isopropyl 2-(3-chloroanilino)-2-oxo-acetate may require experimental determination, understanding these influencing factors provides valuable insights into its behavior in various environments. It is essential to experiment with different solvents and conditions to characterize its solubility accurately.

Interesting facts

Interesting Facts About Isopropyl 2-(3-chloroanilino)-2-oxo-acetate

Isopropyl 2-(3-chloroanilino)-2-oxo-acetate is a fascinating organic compound that has garnered attention in both industrial applications and academic research. Here are some noteworthy aspects of this compound:

  • Versatile Applications: This compound is known for its use in pharmaceuticals as a key building block in the synthesis of various biologically active molecules. Its structure makes it a versatile intermediate for creating complex compounds.
  • Chlorine's Role: The presence of the chloro group in the structure contributes to increased reactivity, allowing for a variety of chemical transformations. This feature is especially valued in medicinal chemistry for developing new drugs.
  • Biological Significance: Compounds with similar structures have been studied for their antimicrobial, anti-inflammatory, and analgesic properties. The potential biological activities of isopropyl 2-(3-chloroanilino)-2-oxo-acetate suggest that it could play a role in future therapeutic developments.
  • Synthetic Pathways: Chemists often explore different reaction pathways to synthesize this compound, leading to rich discussions about green chemistry and sustainable practices. These methods can lead to more efficient processes with less waste generation.
  • Research Potential: Ongoing research continues to unravel the various uses of this compound, making it a subject of interest in both organic synthesis and drug discovery. As scientists seek to modify existing drugs, this compound might serve as a critical precursor.

In summary, isopropyl 2-(3-chloroanilino)-2-oxo-acetate is more than just a chemical formula. Its role in advancing pharmaceutical chemistry and its intriguing structural features make it a compound worth studying for budding chemists and seasoned professionals alike. As noted by chemists, "The journey of a molecular structure can reveal the wonders of chemical innovation."

Synonyms
3'-Chlorooxanilic acid isopropyl ester
U2DZQ48PED
OXANILIC ACID, 3'-CHLORO-, ISOPROPYL ESTER
NSC 58430
NSC-58430
DTXSID40224783
ACETIC ACID, 2-((3-CHLOROPHENYL)AMINO)-2-OXO-, 1-METHYLETHYL ESTER
DTXCID70147274
7399-76-0
Acetic acid, ((2-chlorophenyl)amino)oxo-, 1-methylethyl ester
UNII-U2DZQ48PED
N-(3-Chlorophenyl)oxamidic acid isopropyl ester
Oxanilic acid, isopropyl ester
NSC58430
Oxanilic acid, 3'-chloro-,isopropyl ester
isopropyl 2-(3-chloroanilino)-2-oxo-acetate