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Isopropyl 2-chloroacetate

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Identification
Molecular formula
C5H9ClO2
CAS number
616-71-7
IUPAC name
isopropyl 2-chloroacetate
State
State

Isopropyl 2-chloroacetate is in a liquid state at room temperature. It is usually handled in liquid form across various industrial applications.

Melting point (Celsius)
-29.00
Melting point (Kelvin)
244.15
Boiling point (Celsius)
129.00
Boiling point (Kelvin)
402.15
General information
Molecular weight
136.58g/mol
Molar mass
136.5760g/mol
Density
1.1034g/cm3
Appearence

Isopropyl 2-chloroacetate appears as a colorless liquid. Its physical form is homogeneous, and it is typically used in organic synthesis and as a solvent. The compound is usually stored in cool, well-ventilated areas to prevent degradation.

Comment on solubility

Solubility of Isopropyl 2-chloroacetate

Isopropyl 2-chloroacetate, with the chemical formula C5H9ClO2, is a compound that exhibits moderate solubility in various solvents. Here are some key points regarding its solubility:

  • Polar Solvents: It tends to be soluble in polar solvents such as water, though the solubility is not very high. This can be attributed to its polar ester functional group, which can form hydrogen bonds with water molecules.
  • Non-Polar Solvents: It is more soluble in non-polar solvents like hexane or ethyl acetate. The hydrophobic alkyl chain enhances solubility in such solvents.
  • Temperature Dependence: Like many organic compounds, solubility may increase with temperature, making it important to consider the conditions under which the compound is used.
  • Practical Applications: Due to its solubility characteristics, isopropyl 2-chloroacetate is utilized in organic synthesis, where solubility in various media can impact reaction efficiency.

In summary, while isopropyl 2-chloroacetate has moderate solubility in water, its solubility profile varies significantly with the choice of solvent. This characteristic is essential for its application in different chemical environments.

Interesting facts

Interesting Facts about Isopropyl 2-Chloroacetate

Isopropyl 2-chloroacetate is an intriguing compound that finds its applications and relevance across various fields in chemistry and industry. Here are some fascinating insights into this compound:

  • Chemical Structure: Isopropyl 2-chloroacetate features a chloroacetate functional group which can significantly influence its reactivity and interactions with other chemicals.
  • Synthetic Applications: It serves as a versatile intermediate in organic synthesis, especially in the production of pharmaceutical compounds and agrochemicals. Its capability to undergo transformations makes it a valuable building block.
  • Chirality: The presence of a chiral center in the molecule allows for interesting stereochemical considerations. This is especially important in pharmaceutical chemistry, where the activity of a drug can vary based on its stereoisomerism.
  • Biodegradability: Isopropyl 2-chloroacetate is not just useful in synthesis; it also shows potential for biodegradability, making it an attractive option in the development of environmentally friendly chemicals.
  • Historical Significance: The study of chloroacetic compounds dates back over a century, contributing to advancements in synthetic methods and various applications that we still utilize today.

In summary, Isopropyl 2-chloroacetate stands out due to its reactivity, versatility, and importance in continued chemical research and industrial applications. As future scientists and chemists explore further, this compound may unveil even more potential in diverse fields.

Synonyms
ISOPROPYL CHLOROACETATE
105-48-6
Chloroacetic acid isopropyl ester
propan-2-yl 2-chloroacetate
Acetic acid, chloro-, 1-methylethyl ester
Acetic acid, chloro-, isopropyl ester
CCRIS 7748
isopropyl 2-chloroacetate
VNJ65NL2TF
EINECS 203-301-7
NSC 27789
ClCH2C(O)OCH(CH3)2
AI3-39184
Acetic acid, 2-chloro-, 1-methylethyl ester
NSC-27789
DTXSID6059316
Monochloroacetic acid isopropyl ester
UN2947
Chloroacetic acid, 1-methyl ester
MFCD00040410
UNII-VNJ65NL2TF
SCHEMBL136589
DTXCID3032913
VODRWDBLLGYRJT-UHFFFAOYSA-
chloro-acetic acid isopropyl ester
AAA10548
NSC27789
1-METHYLETHYL MONOCHLOROACETATE
AKOS000268764
chloroacetic acid, 1-methylethyl ester
UN 2947
LS-13055
NS00023378
Acetic acid, chloro-, isopropyl ester (8CI)
Isopropyl chloroacetate [UN2947] [Flammable liquid]
Q63395455
F8889-3074
InChI=1/C5H9ClO2/c1-4(2)8-5(7)3-6/h4H,3H2,1-2H3
203-301-7