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Isopropyl 2-sulfamoylbenzoate

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Identification
Molecular formula
C10H13NO4S
CAS number
3759-67-5
IUPAC name
isopropyl 2-sulfamoylbenzoate
State
State

At room temperature, isopropyl 2-sulfamoylbenzoate is typically in a solid state. The solid is relatively stable and does not sublimate or evaporate under normal conditions.

Melting point (Celsius)
127.00
Melting point (Kelvin)
400.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
243.28g/mol
Molar mass
243.2830g/mol
Density
1.3200g/cm3
Appearence

Isopropyl 2-sulfamoylbenzoate typically appears as a white to off-white crystalline powder. The material is usually uniform in appearance with occasional clumps, depending on the level of hydration or compaction during handling.

Comment on solubility

Solubility of Isopropyl 2-sulfamoylbenzoate

Isopropyl 2-sulfamoylbenzoate is a compound whose solubility characteristics are of considerable interest in various chemical applications. Understanding its solubility can reveal important insights into how it interacts with different solvents and environments. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound tends to be soluble in polar solvents such as water, due to the presence of the sulfamoyl group that can form hydrogen bonds.
  • Organic Solvents: It may also show solubility in common organic solvents like ethanol and methanol, which can facilitate its use in organic synthesis.
  • Temperature Dependency: As with many compounds, the solubility of isopropyl 2-sulfamoylbenzoate can vary significantly with temperature, often increasing with higher temperatures.
  • Crystalline Nature: Its crystalline structure might influence solubility; compounds with well-defined crystalline forms may exhibit limited solubility compared to amorphous materials.

In practice, the solubility of isopropyl 2-sulfamoylbenzoate can be summarized as being reasonably soluble in polar solvents and demonstrating varying levels of solubility in organic solvents based on concentration and temperature conditions. Understanding these solubility parameters is crucial for its application in medicinal chemistry and material science.

Interesting facts

Interesting Facts about Isopropyl 2-Sulfamoylbenzoate

Isopropyl 2-sulfamoylbenzoate is a fascinating compound with various applications in the field of chemistry, particularly in medicinal chemistry. Here are some intriguing points about this compound:

  • Pharmaceutical Use: This compound falls under the category of sulfamoyl derivatives, which are known for their potential therapeutic effects. Sulfamoyl compounds have been studied for their role in treating bacterial infections, often acting as antibacterial agents.
  • Structure and Function: The structural characteristics of isopropyl 2-sulfamoylbenzoate allow it to interact with biological systems in unique ways. The sulfamoyl group is particularly interesting as it can form hydrogen bonds, affecting how the compound interacts with enzymes and proteins.
  • Versatility: Isopropyl 2-sulfamoylbenzoate can serve as a building block for other chemical synthesis. Its functional groups can undergo a variety of chemical reactions, making it a valuable compound in organic synthesis.
  • Research Significance: Ongoing studies are investigating the potential of the sulfamoyl groups in drug discovery, looking particularly at their interaction with different biological targets, which may lead to advancements in the development of new antibiotics.

Overall, isopropyl 2-sulfamoylbenzoate exemplifies how a single compound can have multifaceted roles and implications in both scientific research and practical applications. Its unique properties contribute to the ever-evolving landscape of medicinal chemistry, proving that even the simplest compounds can hold great significance in the scientific community.

Synonyms
SKF 7711
NSC 53646
O-Sulfamoylbenzoic acid isopropyl ester
BRN 2809544
Isopropyl ester of o-sulfamoyl-benzoic acid
UNII-7A6Y732210
SKF-7711
NSC-53646
7A6Y732210
DTXSID10161454
Benzoic acid, 2-(aminosulfonyl)-, 1-methylethyl eter
DTXCID2083945
Benzoic acid, 2-(aminosulfonyl)-, 1-methylethyl eter (9CI)
14065-41-9
propan-2-yl 2-sulfamoylbenzoate
Isopropyl 2-sulfamoylbenzoate
BENZOIC ACID, o-SULFAMOYL-, ISOPROPYL ESTER
TCMDC-142262
Benzoic acid, 2-(aminosulfonyl)-, 1-methylethyl ester
Isopropyl ester of o-sulfamoylbenzoic acid
isopropyl o-sulfamoylbenzoate
WLN: ZSWR BVOY1&1
CHEMBL530277
SCHEMBL8507951
isopropyl 2-(aminosulfonyl)benzoate
NSC53646
DB-416663
Q27266809