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isopropyl N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)carbamate

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Identification
Molecular formula
C14H14N4O2S
CAS number
.
IUPAC name
isopropyl N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)carbamate
State
State

This compound is typically a solid at room temperature.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
536.15
Boiling point (Kelvin)
809.30
General information
Molecular weight
303.35g/mol
Molar mass
303.3530g/mol
Density
1.3723g/cm3
Appearence

Isopropyl N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)carbamate is appears as a crystalline solid, which may vary in color from white to off-white.

Comment on solubility

Solubility of isopropyl N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)carbamate

The solubility of isopropyl N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)carbamate is influenced by several factors. This compound exhibits varying solubility profiles based on the solvent used.

Key Points about its Solubility:

  • Polar Solvents: It is generally more soluble in polar solvents such as water or methanol, due to the presence of polar functional groups within its structure.
  • Non-Polar Solvents: Conversely, it shows limited solubility in non-polar solvents, which can be attributed to a lack of interactions with non-polar molecules.
  • pH Sensitivity: The solubility may also change with varying pH levels, where an increase in acidity might enhance its solubility.

In summary, the solubility of isopropyl N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)carbamate can be effectively maximized by using appropriate solvents and adjusting environmental conditions, demonstrating the critical role that these factors play in the compound's behavior in solution.

Interesting facts

Exploring Isopropyl N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)carbamate

Isopropyl N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)carbamate is a fascinating compound that showcases the intricate relationships between structure, function, and versatility in the realm of organic chemistry. Here are some intriguing aspects to consider:

  • Biodiversity and Applications: This compound represents a unique blend of a thiazole ring and a benzimidazole moiety, which are prominent in many biological systems. Compounds with similar structures often exhibit antimicrobial and anticancer properties, making them subjects of significant research.
  • Pharmacological Potential: The underlying mechanisms of compounds like isopropyl N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)carbamate are of particular interest in medicinal chemistry. Researchers explore their potential as therapeutic agents, especially in targeting specific enzymes or receptors in disease pathways.
  • Research Developments: Ongoing studies often involve the exploration of this compound's derivatives, which can lead to improved efficacy or reduced side effects in pharmacotherapy. The ability to modulate chemical properties through tiny structural changes is a key principle in drug development.
  • Synthesis and Challenges: The synthesis of thiazole and benzimidazole derivatives can be complex, often requiring multi-step reactions. Overcoming challenges during synthesis is a captivating aspect of research, driving innovation and development in synthetic methodologies.

The intricate design of isopropyl N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)carbamate not only emphasizes the beauty of chemical compounds but also highlights the vast potential they hold in the scientific community. As researchers continue to probe its unique properties, this compound remains a promising candidate for future discoveries in medicinal chemistry.

Synonyms
Cambendazole
26097-80-3
Cambendazol
Camvet
Camdan
Cambendazolum
NSC-377071
DTXSID0046852
Isopropyl 2-(4-triazolyl)-5-benzimidazolecarbamate
079X63S3DU
Carbamic acid, (2-(4-thiazolyl)-1H-benzimidazol-5-yl)-, 1-methylethyl ester
DTXCID8026852
Carbamic acid, [2-(4-thiazolyl)-1H-benzimidazol-5-yl]-, 1-methylethyl ester
RefChem:917943
5-Isopropoxycarbonylamino-2-(4-thiazoyl)benzimidazole
propan-2-yl N-(2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazol-5-yl)carbamate
247-459-5
Urokinase
Novazole
Noviben
9039-53-6
Cambenzole
Bonlam
Equiben
CBDZ
MK 905
NSC 377071
propan-2-yl N-[2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-yl]carbamate
Cambendazole (>90%)
MFCD00864552
Carbamic acid, N-[2-(4-thiazolyl)-1H-benzimidazol-6-yl]-, 1-methylethyl ester
5-BENZIMIDAZOLECARBAMIC ACID, 2-(4-THIAZOLYL)-, ISOPROPYL ESTER
NSC377071
NCGC00181110-01
N-(Thiazolyl-4)-2, benzimidazolyl-5, carbamate D'isopropyle
Cambendazole 100 microg/mL in Acetonitrile
NOE [French]
2-(4-Thiazolyl)-5-Isopropoxycarbonylaminobenzimidazole
isopropyl (2-(thiazol-4-yl)-1H-benzo[d]imidazol-5-yl)carbamate
MK 905; NSC 377071; Novazole; Bonlam; Cambendazole; Cambenzole
Urokinase from human urine
Cambendazol [INN-Spanish]
Cambendazolum [INN-Latin]
Cambendazole [USAN:INN:BAN]
EINECS 247-459-5
BRN 0563292
UNII-079X63S3DU
Cambendazol?
Camdan (TN)
CAMBENDAZOLE [MI]
N-(Thiazolyl-4)-2, benzimidazolyl-5, carbamate d'isopropyle [French]
Urolinase from human urine
Cambendazole (USAN/INN)
CAMBENDAZOLE [INN]
CAMBENDAZOLE [USAN]
SCHEMBL44000
CAMBENDAZOLE [MART.]
Isopropyl 2-(4-thiazolyl)-5-benzimidazolecarbamate
MLS004712049
CAMBENDAZOLE [WHO-DD]
CHEMBL290578
orb1304281
SCHEMBL2895694
SCHEMBL29409263
CAMBENDAZOLE [GREEN BOOK]
EX-A752
MSK5515
BCP07866
Cambendazol; Cambendazole; Novazole
Tox21_112724
AKOS037515510
DB11380
NCGC00181110-02
AC-33587
DA-33500
SMR003475014
TS-08767
CAS-26097-80-3
HY-107483
CS-0028606
NS00009532
D03340
Cambendazole, VETRANAL(TM), analytical standard
F554509
5-Isopropoxycarbonylamino-2-(4-thiazolyl)benzimidazole
Q15726127
isopropyl N-(2-thiazol-4-yl-1H-benzimidazol-5-yl)carbamate
isopropyl N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)carbamate
Isopropyl 2-(1,3-thiazol-4-yl)-1H-benzimidazol-5-ylcarbamate #
(Methylethyloxy)-N-(2-(1,3-thiazol-4-yl)benzimidazol-5-yl)methanamide
propan-2-yl N-[2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazol-6-yl]carbamate