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Isopropyl nitrite

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Identification
Molecular formula
C3H7NO2
CAS number
541-42-4
IUPAC name
isopropyl nitrite
State
State

At room temperature, isopropyl nitrite is a liquid. Being volatile, it is often used in various applications requiring liquid nitrites.

Melting point (Celsius)
-106.00
Melting point (Kelvin)
167.15
Boiling point (Celsius)
40.50
Boiling point (Kelvin)
313.65
General information
Molecular weight
89.09g/mol
Molar mass
89.0910g/mol
Density
0.8729g/cm3
Appearence

Isopropyl nitrite is a colorless or pale yellow liquid. It is typically clear and can sometimes have a slightly fruity odor.

Comment on solubility

Solubility of Isopropyl Nitrite

Isopropyl nitrite, with the chemical formula C3H7NO2, exhibits unique solubility characteristics that are important to understand, especially in various chemical applications.

General Solubility

This compound is known to be:

  • Soluble in organic solvents: Isopropyl nitrite readily dissolves in non-polar organic solvents such as ether and benzene.
  • Partially soluble in water: While it has some solubility in water, it is limited due to its hydrophobic hydrocarbon chain.

Factors Affecting Solubility

The solubility of isopropyl nitrite can be influenced by several factors:

  • Temperature: Increased temperature can enhance solubility in both organic and aqueous phases.
  • pH of the solution: The degree of protonation or deprotonation can alter its solubility properties.

In summary, while isopropyl nitrite demonstrates variable solubility with a strong preference for organic media, it is crucial to consider both controlling factors and the specific application context when working with this compound. Its solubility profile makes it valuable in specific chemical reactions and applications, providing flexibility in laboratory settings.

Interesting facts

Interesting Facts about Isopropyl Nitrite

Isopropyl nitrite is a fascinating compound with a variety of applications and intriguing properties. Here are some compelling details about this chemical:

  • Chemical Family: Isopropyl nitrite belongs to the class of alkyl nitrites, which are recognized for their vasodilating effects. This means they can relax blood vessels, enhancing blood flow.
  • Historical Significance: Although not widely known, isopropyl nitrite has historical ties to the gay community in the 1970s, where it was popularized for its recreational use, often referred to as "poppers."
  • Role in Medicine: In medical settings, alkyl nitrites, including isopropyl nitrite, have been utilized intermittently for the treatment of angina. However, they are primarily used in non-medical contexts today.
  • Mechanism of Action: When inhaled, isopropyl nitrite promotes the relaxation of smooth muscle, leading to a quick, temporary drop in blood pressure and increased heart rate, which can be euphoric for users.
  • Health Considerations: While there are anecdotal reports of the pleasurable effects of inhaling isopropyl nitrite, it’s essential to note that improper use can lead to health risks such as headaches, dizziness, and in severe cases, methemoglobinemia—a condition where hemoglobin is unable to carry oxygen effectively.
  • Regulatory Status: In many regions, isopropyl nitrite is not classified as a controlled substance, but regulatory frameworks continue to evolve, reflecting ongoing concerns about its misuse and effects.

In conclusion, isopropyl nitrite is more than just a simple chemical compound; it carries a rich history and multifaceted implications in both recreational and medical contexts. As with any chemical substance, understanding its properties and effects is crucial for safe handling and responsible use.

Synonyms
Isopropyl nitrite
2-Propanol nitrite
Nitrous acid, 1-methylethyl ester
NITROUS ACID, ISOPROPYL ESTER
UNII-2T3Y2PS0ZE
EINECS 208-779-0
Nitrous acid isopropyl ester
2T3Y2PS0ZE
Isopropylester kyseliny dusite
Isopropylester kyseliny dusite [Czech]
BRN 1698878
Nitrous acid 1-methylethyl ester
ISOPROPYL NITRITE [MI]
DTXSID3052191
4-01-00-01474 (Beilstein Handbook Reference)
DTXCID8030762
208-779-0
541-42-4
propan-2-yl nitrite
ISOPROPYLNITRITE
iso-Propyl nitrite
nitrous acid propan-2-yl ester
AKOS006272058
DB-004045
NS00032972
A829987
Q15409423