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Isoquinolin-5-ol

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Identification
Molecular formula
C9H7NO
CAS number
7461-01-8
IUPAC name
isoquinolin-5-ol
State
State
At room temperature, Isoquinolin-5-ol is typically in a solid state, often observed as a crystalline or powdery substance.
Melting point (Celsius)
130.00
Melting point (Kelvin)
403.20
Boiling point (Celsius)
342.50
Boiling point (Kelvin)
615.60
General information
Molecular weight
145.16g/mol
Molar mass
145.1620g/mol
Density
1.2658g/cm3
Appearence

Isoquinolin-5-ol is a crystalline compound that appears as a white to off-white solid. The actual color can vary slightly depending on the purity and form of the compound.

Comment on solubility

Solubility of Isoquinolin-5-ol

Isoquinolin-5-ol, a compound noted for its unique structural characteristics, exhibits a moderate solubility profile in various solvents. Key points regarding its solubility include:

  • Solvent Compatibility: It is generally soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), but it displays limited solubility in polar solvents like water.
  • Concentration Effects: Its solubility can increase with temperature; as temperature rises, solute interactions in solvents become more favorable.
  • pH Influence: The solubility of isoquinolin-5-ol may also be impacted by the pH of the solution, due to potential protonation of the hydroxyl group under acidic conditions.
  • Practical Applications: Understanding the solubility helps in its formulation for applications in biomedical and pharmaceutical fields, where solubility plays a crucial role in drug efficacy.

In summary, while isoquinolin-5-ol shows a preference for organic solvents and exhibits an interesting relationship with temperature and pH, it is important to consider these factors for effective usage in research and application.

Interesting facts

Interesting Facts About Isoquinolin-5-ol

Isoquinolin-5-ol is a fascinating compound that falls under the category of heterocyclic organic compounds. This compound is of particular interest in various fields due to its unique structure and properties. Here are some intriguing aspects of isoquinolin-5-ol:

  • Structural Characteristics: Isoquinolin-5-ol features a bicyclic structure that includes both an aromatic ring and a nitrogen atom.
  • Biological Significance: Many derivatives of isoquinolin-5-ol have demonstrated important biological activities, making it a compound of interest in medicinal chemistry.
  • Natural Occurrence: Isoquinolin-5-ol is a part of several natural products and is often found in plants, contributing to their pharmacological effects.
  • Synthesis and Research: Its synthesis can be accomplished through various methods, such as the reaction of appropriate precursors, which is an area of active research.
  • Applications: Beyond its biological implications, isoquinolin-5-ol derivatives are also explored for use in materials science, as they may contribute to the development of new electronic materials.

As a compound with potential in both pharmacology and materials science, isoquinolin-5-ol represents a convergence of interests within the scientific community. Researchers continue to explore its properties and applications, striving to unlock even more of its potential. As one scholar once stated, "The complexity of nature often yields the simplest of solutions when we study compounds like isoquinolin-5-ol."

Synonyms
5-Hydroxyisoquinoline
Isoquinolin-5-ol
EINECS 219-456-9
NSC 51787
AI3-61885
219-456-9
RefChem:792279
2439-04-5
5-Isoquinolinol
5-Hydroxy-isoquinoline
MFCD00006906
CHEMBL57481
MLS000737285
5-Isoquinolinol; NSC 51787;
NSC51787
NoName_813
isoquinoline, 5-hydroxy-
Oprea1_051337
SCHEMBL276517
SCHEMBL276518
5-Isoquinolinol;NSC 51787
SCHEMBL27524975
DTXSID30901677
HMS1618B04
HMS2748D05
BBL027623
BDBM50240538
NSC-51787
STK833029
AKOS005259348
CS-W004721
FH24373
HY-W004721
NCGC00246945-01
DS-10757
SMR000035084
SY021130
DB-029159
5-Hydroxyisoquinoline, technical grade, 90%
H1259
NS00048316
ST50823965
A26441
EN300-110060
578H676
doi:10.14272/CSNXUYRHPXGSJD-UHFFFAOYSA-N.1
Q27455996
F0001-2982
5SG