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Ethyl isothiocyanate

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Identification
Molecular formula
C3H5NS
CAS number
542-85-8
IUPAC name
isothiocyanatoethane
State
State

At room temperature, ethyl isothiocyanate is in the liquid state. It is volatile and may emit vapors, particularly at elevated temperatures.

Melting point (Celsius)
-111.00
Melting point (Kelvin)
162.15
Boiling point (Celsius)
133.50
Boiling point (Kelvin)
406.65
General information
Molecular weight
99.17g/mol
Molar mass
99.1650g/mol
Density
0.9413g/cm3
Appearence

Ethyl isothiocyanate appears as a colorless liquid with a pungent odor. It tends to have a distinct sulfur-like smell due to the isothiocyanate group.

Comment on solubility

Solubility of Isothiocyanatoethane

Isothiocyanatoethane, with the chemical formula C2H4N2S, exhibits interesting solubility characteristics that can impact its applications in various fields. The solubility of this compound can be summarized as follows:

  • Polar Characteristics: Isothiocyanatoethane contains both polar and nonpolar functional groups, which can enhance its solubility in various solvents.
  • Solvent Compatibility: This compound is generally soluble in organic solvents like alcohols, ethers, and some hydrocarbons due to its chemical structure.
  • Water Solubility: While not highly soluble in water, isothiocyanatoethane can still dissolve to some extent, typically influenced by temperature and specific ionic interactions.

In practical terms, the solubility of isothiocyanatoethane makes it suitable for use in a variety of chemical reactions, including those involving nucleophiles and electrophiles. As such, understanding its solubility profile is crucial for its application in synthesis and as a reagent.

Overall, the solubility aspects of isothiocyanatoethane can be depicted as a balance between its polar and nonpolar characteristics, facilitating its use in diverse chemical settings.

Interesting facts

Interesting Facts about Isothiocyanatoethane

Isothiocyanatoethane, commonly known in the field of chemistry as a compound with intriguing properties, belongs to the family of isothiocyanates. These compounds are recognized for their unique reactivity and biological significance.

Origins and Structure

This compound can be envisioned as a derivative of ethylamine where a sulfur atom replaces the oxygen in the structure, leading to the formation of a functional group characterized by the presence of –N=C=S. The underlying structure offers a fascinating perspective on how minor changes can drastically alter properties in organic compounds.

Key Characteristics

  • Reactivity: Isothiocyanatoethane is renowned for its versatility in organic synthesis, often participating in nucleophilic reactions.
  • Biological Significance: Many isothiocyanates are known for their potential health benefits, particularly in anti-cancer properties, an area of ongoing research.
  • Flavor Compound: The compound is also associated with sharp, pungent flavors, reminiscent of cruciferous vegetables, which may contribute to its role in plant defense mechanisms.

Applications in Research

In the laboratory, isothiocyanatoethane serves different purposes. Some of its applications include:

  • Synthesis: It acts as a reactive intermediate in the preparation of various organic compounds.
  • Biochemical Studies: Researchers exploit its properties to explore cellular mechanisms, particularly in relation to human health.
  • Plant Biology: Understanding its role in plant defense can lead to advancements in agricultural science.

Conclusion

In summary, isothiocyanatoethane exemplifies the intricate relationship between molecular structure and function. With its vivid applications and potential health benefits, it captivates both chemists and biologists alike, making it a particularly noteworthy topic in the study of chemical compounds.

Synonyms
Ethyl isothiocyanate
Isothiocyanatoethane
Ethane, isothiocyanato-
ETHYLISOTHIOCYANATE
Isothiocyanic acid, ethyl ester
CCRIS 7323
EINECS 208-831-2
NSC 84212
NSC-84212
UNII-3284MJ2T8P
FEMA NO. 4420
CHEBI:85098
AI3-18428
3284MJ2T8P
DTXSID2060258
ETHYL ISOTHIOCYANATE [MI]
ETHYL ISOTHIOCYANATE [FHFI]
Ethyl isothiocyanic acid
Isothiocyanate, ethyl ester
DTXCID6041632
208-831-2
hbnyjwafdzlwrs-uhfffaoysa-n
542-85-8
MFCD00004820
isothiocyanato-ethane
Ethyl isothiocyanate, 97%
Isothiocyanic Acid, Ethyl Ester; Isothiocyanatoethane; 1-Isothiocyanatoethane;
ethylisothio-cyanate
1-Isothiocyanatoethane #
Isothiocyanic Acid Ethyl Ester
CHEMBL2251727
BCP05940
NSC84212
STL194264
AKOS000119775
I0188
NS00022345
EN300-19657
D94745
Q27158332
F0001-1427