Skip to main content

Methanesulfonyl fluoride

ADVERTISEMENT
Identification
Molecular formula
CH3SO2F
CAS number
368-11-2
IUPAC name
methanesulfonyl fluoride
State
State

At room temperature, methanesulfonyl fluoride is a liquid. It transitions from a liquid to a gas when it reaches its boiling point of 104.5 °C.

Melting point (Celsius)
-33.00
Melting point (Kelvin)
240.15
Boiling point (Celsius)
104.50
Boiling point (Kelvin)
377.65
General information
Molecular weight
98.11g/mol
Molar mass
98.1060g/mol
Density
1.3640g/cm3
Appearence

Methanesulfonyl fluoride is a colorless liquid with a pungent odor. It is typically found in laboratories where it is used in chemical synthesis and reactions.

Comment on solubility

Solubility of Methanesulfonyl Fluoride

Methanesulfonyl fluoride (CH32

Some key points regarding the solubility of methanesulfonyl fluoride include:

  • Polar Nature: The presence of the sulfonyl group (–SO2) contributes to its polar character, making it soluble in polar solvents.
  • Solvent Compatibility: Methanesulfonyl fluoride is known to be soluble in:
    • Water: Due to its polar nature, it has decent solubility in water.
    • Alcohols: It shows good solubility in alcohols such as ethanol and methanol.
    • Organic Solvents: It is compatible with a range of organic solvents, which expands its utility in synthesis.
  • Temperature Dependent: Solubility can vary significantly with temperature, often increasing in warmer conditions.
  • Reactivity: It’s essential to consider that methanesulfonyl fluoride can react with certain compounds, which may affect its solubility in those contexts.

In summary, methanesulfonyl fluoride demonstrates noteworthy solubility in polar solvents, making it a versatile compound in various chemical contexts. Its ability to dissolve in both organic solvents and water showcases its importance in chemical processes. For optimal use and reactions, one should always take into account the solvent system and environmental conditions.

Interesting facts

Interesting Facts about Methanesulfonyl Fluoride

Methanesulfonyl fluoride, often abbreviated as MSF, is a fascinating compound in the world of chemistry. It is renowned for its unique properties and applications, making it a critical compound in various fields. Here are some noteworthy aspects:

  • Versatile Reagent: MSF is used as a reagent in organic synthesis. Its ability to introduce the methanesulfonyl group makes it valuable for creating sulfonamides and for various functional group transformations.
  • Pharmaceutical Applications: This compound plays a significant role in the pharmaceutical industry, particularly in drug development. It is often employed in the synthesis of biologically active molecules.
  • Environmental Impact: Methanesulfonyl fluoride is considered a potent greenhouse gas; however, its atmospheric lifetime is relatively short compared to other compounds. Understanding its behavior in the environment is crucial for ecological studies.
  • Mechanism of Action: In organic chemistry, MSF acts as a potent electrophile, with its reactivity attributed to the sulfonyl group. This characteristic makes it invaluable for reactions that require strong electrophilic species.
  • Safety Precautions: Due to its toxicity, handling methanesulfonyl fluoride requires careful safety measures. It is essential to work in well-ventilated areas and utilize appropriate personal protective equipment (PPE).

The compound's significance extends beyond simple reactions; it serves as a bridge connecting various realms of synthetic chemistry. As researchers explore its potential, methanesulfonyl fluoride continues to illustrate the intricate dance of atoms and molecules that define chemical innovation.

Synonyms
METHANESULFONYL FLUORIDE
Fumette
Mesyl fluoride
Fluoro methyl sulfone
Methanesulphonyl fluoride
HSDB 6397
EINECS 209-192-2
UNII-9H250YYY0R
BRN 1740836
9H250YYY0R
SNX-001
DTXSID8060329
4-04-00-00027 (Beilstein Handbook Reference)
methylsulfonylfluoride
methylsulfonyl fluoride
DTXCID1041970
knwqlfoxpqzgpx-uhfffaoysa-n
un2927
558-25-8
MSF
methylsufonyl fluoride
methanesulfonyl-fluoride
methane sulfonyl fluoride
CH3SO2F
Methanesulfonyl fluoride, 98%
CHEMBL4297433
AKOS005207314
DB13058
FM181569
DB-052808
NS00033407
EN300-35716
A830828
Q6823571
BRD-K53896891-001-01-2
Z361886230