Skip to main content

Methyl nicotinate

ADVERTISEMENT
Identification
Molecular formula
C7H9NO2
CAS number
93-60-7
IUPAC name
methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate
State
State

Methyl nicotinate is typically a liquid at room temperature. It can appear as a solid under cooler conditions, but its standard form at ambient temperatures is liquid.

Melting point (Celsius)
-4.70
Melting point (Kelvin)
268.50
Boiling point (Celsius)
210.40
Boiling point (Kelvin)
483.60
General information
Molecular weight
151.16g/mol
Molar mass
151.1610g/mol
Density
1.1200g/cm3
Appearence

Methyl nicotinate is a colorless to pale yellow liquid. It has a faint characteristic odor, which is often described as fruity or floral. The compound is typically available in its liquid form at room temperature, but it can also solidify when cooled.

Comment on solubility

Solubility of Methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate

Methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate, with the chemical formula C7H9NO2, exhibits interesting solubility characteristics that can be influenced by various factors. Generally, the solubility of this compound can be characterized as follows:

  • Polar Solvents: This compound is likely to be soluble in polar solvents such as water and alcohols due to its carboxylate group.
  • Non-Polar Solvents: It may show limited solubility in non-polar solvents like hexane or benzene, primarily due to hydrophobic interactions.
  • Temperature Influence: Like many organic compounds, solubility tends to increase with temperature; therefore, warming the solvent can enhance the dissolution process.

It is also important to note that solubility can be influenced by pH levels, as the presence of acidic or basic conditions may affect the ionization state of the compound. As a result, its solubility characteristics are not just a matter of the compound itself but also of the surrounding environment.

In summary, the solubility of methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate is a complex interplay of its chemical structure and environmental conditions. Understanding these parameters can significantly enhance the efficiency of its applications.

Interesting facts

Interesting Facts About Methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate

Methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate is a fascinating compound that belongs to the pyridine family, known for its diverse applications in both organic chemistry and pharmaceutical development. Below are some engaging insights into this compound:

  • Nitrogen-Containing Heterocycles: This compound features a pyridine ring, which is a nitrogen-containing heterocycle. These types of compounds are pivotal due to their significant roles in biological systems and their presence in various natural products.
  • Pharmaceutical Importance: Pyridine derivatives, such as this one, contribute to the development of various drugs. They are found in several medications due to their potential to interact favorably with biological receptors.
  • Synthetic Pathways: The synthesis of methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate often involves multi-step organic reactions, showcasing the complexity and creativity involved in organic synthesis.
  • Versatile Building Block: Chemists often use compounds like this one as building blocks for synthesizing more complex molecules, making them invaluable in material science and medicinal chemistry.

In the words of famous chemist Robert H. Grubbs, “Chemistry is the science of connections.” Each connection revealed in compounds like methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate opens pathways to innovations that can significantly impact health and industry.

Whether you are a chemistry student diving into organic synthesis or a seasoned chemist exploring the intricacies of drug design, understanding compounds like this one enhances your grasp of the foundational elements of chemical science.

Synonyms
arecoline
63-75-2
Arecolin
Arecaline
Arecholine
Methylarecaiden
Methylarecaidin
Arekolin
Arecoline base
Arecaidine methyl ester
3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester
Arecholin
methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate
Methyl N-methyltetrahydronicotinate
methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate
N-Methyltetrahydronicotinic acid, methyl ester
Methyl 1,2,5,6-tetrahydro-1-methylnicotinate
NSC 56321
C8H13NO2
CCRIS 7688
Methyl N-methyl-1,2,5,6-tetrahydronicotinate
EINECS 200-565-5
NSC-56321
1,2,5,6-Tetrahydro-1-methylnicotinic acid, methyl ester
BRN 0123045
4ALN5933BH
CHEBI:2814
DTXSID3022617
NICOTINIC ACID, 1,2,5,6-TETRAHYDRO-1-METHYL-, METHYL ESTER
1-Methyl-delta(sup 3,4)tetrahydro-3-pyridinecarboxylate
ARECOLINE [MI]
1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic acid methyl ester
DTXCID502617
63-75-2 (free)
N-Methyltetrahydropyridine-beta-carboxylic acid methyl ester
1-Methyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid methyl ester
methyl 1-methyl-5,6-dihydro-2H-pyridine-3-carboxylate
NCGC00015075-04
Methyl 1,2,5, 6-tetrahydro-1-methylnicotinate
Methyl N-methyl-1,2,5, 6-tetrahydronicotinate
N-Methyl-.delta.-tetrahydronicotinic acid methyl ester
Methyl 1-methyl-1,2,5,6-tetrahydro-3-pyridinecarboxylate
N-Methyltetrahydropyridine-.beta.-carboxylic acid methyl ester
MLS000028840
Arecaidine methyl ester;Arecoline base;Methyl arecaidin; Methylarecaidine; NSC56321
CAS-63-75-2
SMR000058258
UNII-4ALN5933BH
Arecoline_major
Methylarecaidine
MFCD00059167
arecoline;hydrobromide
Spectrum_000055
Prestwick0_000402
Prestwick1_000402
Prestwick2_000402
Prestwick3_000402
Spectrum2_000051
Spectrum3_001387
Spectrum4_000810
Spectrum5_001316
Lopac-A-6134
cid_9301
CHEMBL7303
Lopac0_000049
SCHEMBL44065
BSPBio_000324
BSPBio_002974
GTPL296
KBioGR_001299
KBioSS_000435
DivK1c_000810
SPBio_000201
SPBio_002263
BPBio1_000358
MEGxp0_001891
ACon1_002372
BDBM46858
KBio1_000810
KBio2_000435
KBio2_003003
KBio2_005571
KBio3_002194
pyranosyl)-?-D-galactopyranoside
NINDS_000810
WLN: T6N CUTJ A1 CVO1
ALBB-035732
NSC56321
Tox21_110079
BBL036229
AKOS000520752
Tox21_110079_1
CCG-204145
DB04365
SB54186
SDCCGMLS-0066647.P001
SDCCGSBI-0050038.P004
IDI1_000810
NCGC00015075-01
NCGC00015075-02
NCGC00015075-03
NCGC00015075-05
NCGC00015075-06
NCGC00015075-07
NCGC00015075-10
NCGC00015075-19
NCGC00162053-01
NCGC00162053-02
NCGC00162053-03
AC-34025
CAS-300-08-3
N-Methyl-beta-carboxylic acid methyl ester
SBI-0050038.P003
1ST170173
Methyl N-methyl-1,5,6-tetrahydronicotinate
N-Methyl-beta -carboxylic acid methyl ester
CS-0022545
Methyl 1,5,6-tetrahydro-1-methylnicotinate
NS00002617
EN300-40737
AB00053580_08
AB00053580_09
L000795
Q423515
SR-01000075307-9
BRD-K88646909-004-05-5
BRD-K88646909-004-06-3
BRD-K88646909-004-10-5
BRD-K88646909-004-15-4
BRD-K88646909-004-16-2
1,5,6-Tetrahydro-1-methylnicotinic acid, methyl ester
Nicotinic acid,2,5,6-tetrahydro-1-methyl-, methyl ester
Methyl 1-methyl-1,2,5,6-tetrahydro-3-pyridinecarboxylate #
3-Pyridinecarboxylic acid,2,5,6-tetrahydro-1-methyl-, methyl ester
methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate;hydrobromide
1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic acid, methyl ester
4-Nitrophenyl 2-Acetamido-2-deoxy-(6-O-2-acetamido-2-deoxy-?-D-gluco-
1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid methyl ester;hydrobromide
200-565-5