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Methyl 1-methyl-4-oxo-piperidin-1-ium-3-carboxylate chloride

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Identification
Molecular formula
C9H14ClNO3
CAS number
157305-28-7
IUPAC name
methyl 1-methyl-4-oxo-piperidin-1-ium-3-carboxylate;chloride
State
State

At room temperature, this compound is in a solid state.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.15
General information
Molecular weight
222.70g/mol
Molar mass
222.7000g/mol
Density
1.2500g/cm3
Appearence

Methyl 1-methyl-4-oxo-piperidin-1-ium-3-carboxylate chloride is typically a white or off-white crystalline solid.

Comment on solubility

Solubility of Methyl 1-methyl-4-oxo-piperidin-1-ium-3-carboxylate; chloride

The solubility of methyl 1-methyl-4-oxo-piperidin-1-ium-3-carboxylate; chloride can be understood through several important aspects:

  • Polarity: Due to its piperidine structure and the presence of carboxylate and quaternary ammonium functionalities, this compound exhibits significant polarity, which generally enhances its solubility in polar solvents such as water.
  • Hydrogen Bonding: The carboxylate group can participate in hydrogen bonding, offering increased interactions with solvent molecules, which aids in its dissolution.
  • Effect of Chloride: The chloride ion can contribute to the overall solubility in aqueous solutions by balancing the charge and promoting interaction with water molecules.

In summary, the expected solubility behavior of methyl 1-methyl-4-oxo-piperidin-1-ium-3-carboxylate; chloride is characterized by:

  1. High solubility in polar solvents (notably water) due to its ionic nature and polar functional groups.
  2. Limited solubility in non-polar solvents because of its hydrophilic characteristics.

Understanding these solubility aspects is crucial for applications in medicinal chemistry, where solubility affects bioavailability and therapeutic effectiveness.

Interesting facts

Interesting Facts about Methyl 1-Methyl-4-Oxo-Piperidin-1-Ium-3-Carboxylate; Chloride

Methyl 1-methyl-4-oxo-piperidin-1-ium-3-carboxylate; chloride is a fascinating compound noteworthy for various reasons in the field of chemistry and pharmaceutical research. Here are some intriguing points:

  • Structural Complexity: This compound features a piperidine ring, a common motif in organic and medicinal chemistry, which contributes to its biological activity and interaction with various biological targets.
  • Quaternary Ammonium Ion: The presence of a positively charged quaternary nitrogen atom makes it interesting for studies related to ionic interactions and solubility, influencing its behavior in different environments.
  • Potential Biological Activity: Compounds with piperidine derivatives have been known to exhibit diverse pharmacological properties, making this compound a candidate for further drug development and biological exploration.

Applications and Research Potential

This compound's structure suggests potential applications in:

  • Drug Design: Due to its unique structural attributes, it may play a role in the synthesis of new therapeutic agents.
  • Material Science: The ionic nature of its chloride form could open avenues for the development of new materials, particularly in ionic conductors or polymer hosts.

Moreover, as a student or researcher, you might find it exciting to explore its reactivity patterns, synthesis pathways, and possible modifications for enhanced activity. As the great chemist Marie Curie once said, "One never notices what has been done; one can only see what remains to be done." This statement truly resonates with the ongoing work in the field of organic compounds, suggesting that there is always more to discover about such intriguing molecular structures!

Synonyms
1-Methyl-4-oxonipecotic acid methyl ester hydrochloride
methyl 1-methyl-4-oxopiperidin-1-ium-3-carboxylate;chloride
NSC 113589
NIPECOTIC ACID, 1-METHYL-4-OXO-, METHYL ESTER, HYDROCHLORIDE
3-Piperidinecarboxylic acid, 1-methyl-4-oxo-, methyl ester, hydrochloride
AKOS015918418