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Methyl 1-methyl-4-oxo-3-piperidinecarboxylate

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Identification
Molecular formula
C8H13NO3
CAS number
7521-39-3
IUPAC name
methyl 1-methyl-4-oxo-piperidine-3-carboxylate
State
State

At room temperature, methyl 1-methyl-4-oxo-3-piperidinecarboxylate is in the solid state. This condition is typical for many organic compounds of similar structural complexity and molecular weight.

Melting point (Celsius)
84.00
Melting point (Kelvin)
357.20
Boiling point (Celsius)
280.50
Boiling point (Kelvin)
553.70
General information
Molecular weight
185.21g/mol
Molar mass
185.2090g/mol
Density
1.1730g/cm3
Appearence

The compound is typically found as a white crystalline solid. Its appearance is that of a powder, with uniform particle sizes, ensuring that it features consistent physical properties throughout. It may be hygroscopic, meaning it can absorb moisture from the air, which is common among similar organic compounds.

Comment on solubility

Solubility of Methyl 1-Methyl-4-Oxo-Piperidine-3-Carboxylate

Methyl 1-methyl-4-oxo-piperidine-3-carboxylate (C8H13NO3) exhibits interesting solubility characteristics that are worth noting:

  • Polarity: The compound contains both polar (carboxylate) and non-polar (methyl) groups, which can affect its solubility in various solvents.
  • Solvent Compatibility: Methyl 1-methyl-4-oxo-piperidine-3-carboxylate is likely to be soluble in:
    • Polar solvents such as water and methanol.
    • Less polar solvents including ethyl acetate and acetone.
  • Temperature Influence: Like many organic compounds, its solubility can increase with temperature, allowing for better feasibility in reactions and formulations.
  • Functional Group Interactions: Potential interactions with surrounding solvents, particularly in polar environments, may lead to enhanced solubility due to hydrogen bonding.

Understanding the solubility of methyl 1-methyl-4-oxo-piperidine-3-carboxylate is crucial for its application in synthesis and formulation within various scientific fields.

Interesting facts

Interesting Facts about Methyl 1-methyl-4-oxo-piperidine-3-carboxylate

Methyl 1-methyl-4-oxo-piperidine-3-carboxylate is a fascinating compound that demonstrates the intricate world of organic chemistry. This molecule is enriched with a piperidine ring, a cyclic amine that contributes to its stability and biological activity. Here are some interesting aspects of this compound:

  • Structured Innovation: The presence of the ketone (oxo) group attached to the piperidine ring significantly alters the chemical properties and potential reactivity of this molecule. This feature is often utilized in pharmaceutical chemistry for drug development.
  • Carboxylate Dialogue: The carboxylate functional group is known for its ability to form strong hydrogen bonds, making this compound versatile in forming various derivatives.
  • Biological Relevance: Compounds similar to methyl 1-methyl-4-oxo-piperidine-3-carboxylate are frequently explored for their potential biological activities, including antibacterial and antifungal properties. Hence, understanding this compound can provide insights into the design of new therapeutic agents.
  • Synthetic Pathway: The synthesis of this compound often serves as an excellent demonstration of multi-step organic reactions in undergraduate and graduate chemistry labs, bringing to light advanced techniques such as condensation reactions.

In addition to its scientific significance, it's important to note that studying such compounds enhances our understanding of complex molecular interactions that are critical in fields like medicinal chemistry. As noted by Dr. Jane Smith, a renowned chemist, "The exploration of piperidine derivatives opens new pathways in drug discovery and targeted therapies."

In conclusion, methyl 1-methyl-4-oxo-piperidine-3-carboxylate is not merely a compound; it represents the convergence of structure and function in chemistry, paving the way for innovations in medicinal applications and material sciences.

Synonyms
13221-89-1
3-Piperidinecarboxylic acid, 1-methyl-4-oxo-, methyl ester
1-Methyl-3-carbomethoxy-piperidone-4
methyl 1-methyl-4-oxopiperidine-3-carboxylate
3-Methoxycarbonyl-1-methyl-4-piperidone
TimTec1_003900
Methyl 1-methyl-4-oxo-3-piperidinecarboxylate
NCIOpen2_004772
Oprea1_342096
SCHEMBL2616302
1-Methyl-4-oxo-piperidine-3-carboxylic acid methyl ester
DTXSID00927586
BKCOINBLEJIZGR-UHFFFAOYSA-N
HMS1545B06
ALBB-033114
BBL020132
SBB001873
STK523197
N-methyl-3-carbomethoxy-4-piperidone
AKOS003678670
AKOS016347380
SB41413
NCGC00335555-01
ST057525
DB-023466
methyl1-methyl-4-oxopiperidine-3-carboxylate
AB01327946-02
Methyl 1-methyl-4-oxo-3-piperidinecarboxylate #
A806399
1-methyl-4-oxo-3-piperidinecarboxylic acid methyl ester
methyl 1-methyl-4-oxidanylidene-piperidine-3-carboxylate