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Strychnine

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Identification
Molecular formula
C21H22N2O2
CAS number
57-24-9
IUPAC name
methyl (1R,12R,19R)-12-[1-(3-methylbut-2-enoyloxy)ethyl]-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,9-tetraene-10-carboxylate
State
State

At room temperature, strychnine is typically found in a solid state. It is often encountered as a white powder.

Melting point (Celsius)
286.00
Melting point (Kelvin)
559.15
Boiling point (Celsius)
308.00
Boiling point (Kelvin)
581.15
General information
Molecular weight
334.44g/mol
Molar mass
334.4370g/mol
Density
1.3638g/cm3
Appearence

Strychnine is a colorless, crystalline alkaloid. It usually appears as a white crystalline powder.

Comment on solubility

Solubility of Methyl (1R,12R,19R)-12-[1-(3-methylbut-2-enoyloxy)ethyl]-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,9-tetraene-10-carboxylate

The solubility of a compound in various solvents is a crucial aspect of its chemical behavior and applications. In the case of methyl (1R,12R,19R)-12-[1-(3-methylbut-2-enoyloxy)ethyl]-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,9-tetraene-10-carboxylate, several factors play a significant role in determining its solubility:

  • Polarity: The compound exhibits a complex molecular structure which can influence its polarity. Polar compounds tend to be soluble in polar solvents, while non-polar compounds dissolve better in non-polar solvents.
  • Functional Groups: The presence of functional groups such as carboxylate can enhance solubility in water, as they can form hydrogen bonds with water molecules.
  • Hydrogen Bonding: This compound might participate in hydrogen bonding with solvents that can donate or accept protons, which can significantly affect solubility.
  • Temperature: Generally, increasing temperature can increase solubility, particularly for solid compounds.

Based on these factors, one might expect the solubility characteristics of this compound to be nuanced. For example, its solubility in water may be influenced by the presence of the carboxylate group, potentially making it more soluble than similar compounds lacking such functional groups. Conversely, the complicated structure may also lead to limited solubility in common organic solvents.

In conclusion, while predicting the solubility of this specific compound requires experimental determination, we can appreciate how chemical structure and environmental conditions intertwine to influence solubility. As the saying goes, "Like dissolves like," and understanding these relationships provides insight into the broader behavior of chemical compounds in various mediums.

Interesting facts

Interesting Facts about Methyl (1R,12R,19R)-12-[1-(3-methylbut-2-enoyloxy)ethyl]-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,9-tetraene-10-carboxylate

This fascinating compound, often referred to by its systematic name, belongs to a class of chemicals known for their complex structures and potential biological activities. Here are some intriguing insights about this compound:

  • Structural Complexity: The presence of multiple interconnected rings in its structure makes this compound a part of the diaza-pentacyclic family. Such complexity is not only fascinating from a structural perspective but also from a synthetic chemistry standpoint.
  • Potential Biological Activity: Compounds featuring similar structural motifs have been investigated for their pharmacological properties. Researchers often probe the potential of such molecules to act as antitumor, antimicrobial, or anti-inflammatory agents, highlighting their importance in medicinal chemistry.
  • Synthetic Challenges: The synthesis of this compound involves intricate multi-step reactions, showcasing the mastery required in modern synthetic organic chemistry. The introduction of functional groups like the ester and the double bond in 3-methylbut-2-enoyloxy reflects the nuances of organic synthesis.
  • Research and Development: Ongoing studies in academia and industry aim to unravel the mechanism of action of compounds like this, encouraging the development of new drugs and therapeutic agents.
  • Natural Inspirations: Many highly complex compounds find their roots in nature; thus, this compound may be inspired by natural products, aiming to mimic or improve their biological activities.

In summary, the exploration of methyl (1R,12R,19R)-12-[1-(3-methylbut-2-enoyloxy)ethyl]-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,9-tetraene-10-carboxylate not only feeds into the vast network of synthetic organic chemistry but also holds promise in the realm of drug discovery and development. Its intricate design allows chemists to study a vast array of properties, ultimately contributing to advancements in medicinal science.

Synonyms
Echitovenidine
BRN 0946842
7222-35-7
Aspidospermidine-3-carboxylic acid, 2,3-didehydro-20-((3-methyl-1-oxo-2-butenyl)oxy)-, methyl ester, (5-alpha,12-beta,19-alpha,20R)-
methyl (1R,12R,19R)-12-[1-(3-methylbut-2-enoyloxy)ethyl]-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,9-tetraene-10-carboxylate
DTXSID20992953
DA-52800
Methyl 20-[(3-methylbut-2-enoyl)oxy]-2,3-didehydroaspidospermidine-3-carboxylate