Interesting facts
Interesting Facts about Methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
This complex compound belongs to a class of substances known for their diverse applications in chemistry and pharmacology. Below are some fascinating aspects that highlight the significance and potential implications of this compound:
- Structural Complexity: The IUPAC name indicates a highly intricate structure with multiple chiral centers, showcasing the beauty of stereochemistry. The presence of various functional groups, such as methoxy and benzoyloxy, amplifies its structural diversity.
- Potential Biological Activity: Compounds derived from yohimbine, which can be traced back to the bark of the African yohimbe tree, are known for their pharmacological effects. Research suggests that such compounds may possess properties beneficial for erectile dysfunction and as potential aphrodisiacs.
- Natural Product Chemistry: This compound's intricate framework and rich natural origins highlight the significance of natural products in medicinal chemistry. It isn’t just an organic molecule; it represents a plethora of bioactive compounds that nature has evolved over millennia.
- Synthesis Challenges: The synthetic pathways leading to such complex molecules involve numerous steps and can face challenges in terms of selectivity and yield. Chemists often strive for greener, more efficient methodologies to synthesize such compounds effectively.
- Applications in Drug Design: The medicinal chemistry field often seeks to modify existing compounds to improve efficacy and reduce side effects. Derivatives of yohimbine, including this compound, may serve as templates for designing new pharmaceuticals.
To quote a famous chemist, "Chemistry is like baking a cake; you have to know the ingredients and the process." This compound demonstrates the intricate balance of its components and the potential for innovative applications in both scientific research and drug development.
In summary, studying compounds like methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate not only enriches our understanding of chemistry but also paves the way for future advancements in health and medicine.
Synonyms
reserpine
50-55-5
Serpalan
Apoplon
Serpasil
Alserin
Hypersil
Sandril
Deserpine
Elserpine
Hiserpia
Rau-Sed
Rausedyl
Rauwasedin
Reserpin
Reserpina
Serpanray
Serpivite
Resine
Rivasin
Serpate
Ascoserpina
Austrapine
Bioserpine
Carditivo
Carrserp
Enipresser
Escaspere
Eserpine
Eskaserp
Eskaserpine
Helfoserpin
Hiposerpil
Hypersine
Idsoserp
Interpina
Lemiserp
Loweserp
Maviserpin
Mayserpine
Mephaserpin
Neoserfin
Purserpine
Quiescin
Raudiford
Raudixoid
Rauloydin
Raumorine
Raunervil
Raunorine
Raupasil
Rausedan
Rausedil
Rauserpine
Rauserpol
Rausingle
Rauwilid
Rauwipur
Rauwoleaf
Resedrex
Reserbal
Resercaps
Resercen
Reserfia
Reserjen
Reserlor
Reserpal
Reserpamed
Reserpanca
Reserpene
Reserpex
Reserpil
Reserpoid
Respital
Roxinoid
Alkarau
Apsical
Banasil
Benazyl
Kitine
Neoserp
Raucap
Raugal
Raulen
Raupoid
Raurine
Rausan
Rautrin
Rauvlid
Rawilid
Reserp
Restran
Riserpa
(-)-Reserpine
Key-serpine
Crystoserpine
Klimanosid
Mallopress
Reserpidefe
Reserpinum
3P Reserp
Carpacil
Gilucard
Hydropine
Hydroserp
Rauwita
Recipin
Resaltex
Resedril
Serpine
Neo-antitensol
Rauserpin-Alk
Hydromox-R
Rese-lar
Reser-ar
Diurese-R
Hydrosine 25
Hydroserpalan
Temposerpine
Eberpine
Reserpur
Residine
Resocalm
Rezerpin
Sedaraupin
Sedaraupina
Serfolia
Serolfia
Serpaloid
Serpasol
Serpazol
Serpentil
Serpentina
Serpicon
Serpiloid
Serpogen
Triserpin
Sandron
Sedserp
Serfin
Serpen
Serpena
Serpoid
Serpone
Sertabs
Sertens
Sertina
Unilord
Roxel
Diupres 250
Diupres 500
l-Carpserp
Vio-Serpine
SK-Reserpine
Hydroserpine Plus
T-Serp
Chloroserp-250
Chloroserp-500
Chloroserpin-250
3,4,5-Trimethoxybenzoyl methyl reserpate
Chloroserpine-500
Hydro-Reserpine-25
Hydro-Reserpine-50
Metatensin
Resperin
Serpipur
Ryser
Tempo-Reserpina
R-e-s
Caswell No. 722A
ENT 50146
Rcra waste number U200
NCI-C50157
V-Serp
Usaf cb-27
CCRIS 550
H 520
HSDB 213
Raunova
Residin
Serpivate
Serpasil premix
Reserpina [INN-Spanish]
EINECS 200-047-9
UNII-8B1QWR724A
Cardioserpin
Hypertensan
NSC-59272
Orthoserpina
Pressimedin
Tensionorme
Adelfan
Adelphin
Alkaserp
Ascoserp
Banisil
Brinderdin
Briserine
Darebon
Ebserpine
Elfanex
Hexaplin
Hydropres
Idoserp
Modenol
Neoslowten
Perskleran
Raudixin
Reserutin
Resperine
Salupres
Seominal
Serp-AFD
Serpilum
Supergan
Tensanyl
Tensional
Terbolan
Transerpin
Tylandril
Abesta
Abicol
EPA Pesticide Chemical Code 123101
NSC 237659
NSC-237659
BRN 0102014
8B1QWR724A
Hypercal B
DTXSID7021237
CHEBI:28487
Renese R
AI3-50146
NSC59272
Serpine (pharmaceutical)
ENT-50146
MFCD00005091
CHEMBL772
Methyl reserpate 3,4,5-trimethoxybenzoic acid ester
Broserpine
Sederaupin
Serpaneurona
Tefaserpina
Tenserpinie
Tepserpine
Eberspine
Reserpka
Resiatric
Rivased
Rolserp
Roxynoid
Serpazil
Serpedin
Serpentin
Serpyrit
Sertensin
Serpil
Hypertane forte
Solfo serpine
DTXCID201237
50-55-5 (free)
Reserpic acid methyl ester 3,4,5-trimethoxybenzoate (ester)
Yohimban-16-carboxylic acid,11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester,(3b,16b,17a,18b,20a)-
.gamma.-Serpine
Reserpine [USP:INN:BAN:JAN]
Butiserpazide-25
UNIPRES COMPONENT RESERPINE
Marnitension simple
DRALSERP COMPONENT RESERPINE
NAQUIVAL COMPONENT RESERPINE
REGROTON COMPONENT RESERPINE
4-25-00-01319 (Beilstein Handbook Reference)
HYDROPRES COMPONENT RESERPINE
RENESE-R COMPONENT RESERPINE
HYDRAP-ES COMPONENT RESERPINE
CAM-AP-ES COMPONENT RESERPINE
METATENSIN COMPONENT RESERPINE
SALUTENSIN COMPONENT RESERPINE
SER-A-GEN COMPONENT RESERPINE
SER-AP-ES COMPONENT RESERPINE
Metatensin #2
Metatensin #4
H.R.-50 COMPONENT RESERPINE
HYDROMOX R COMPONENT RESERPINE
11,17-Dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)yohimban-16-carboxylic acid methyl ester
component of Naquival
component of Regroton
DIUTENSEN-R COMPONENT RESERPINE
Hydropres 25
Hydropres 50
(3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester
HYDRO-RESERP COMPONENT RESERPINE
component of Renese R
DEMI-REGROTON COMPONENT RESERPINE
component of Metatensin
gammaserpine
nembuserpin
NCGC00091250-04
SERPASIL-ESIDRIX COMPONENT RESERPINE
neo-serp
RESERPINE (IARC)
RESERPINE [IARC]
component of Butiserpazide
Reserpina (INN-Spanish)
SERPASIL-APRESOLINE COMPONENT RESERPINE
RESERPINE (MART.)
RESERPINE [MART.]
Hydroserpine #1
RESERPINE (USP-RS)
RESERPINE [USP-RS]
3-beta,20-alpha-Yohimban-16-beta-carboxylic acid, 18-beta-hydroxy-11,17-alpha-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate (ester)
methyl (1S,2R,3R,4aS,13bR,14aS)-2,11-dimethoxy-3-((3,4,5-trimethoxybenzoyl)oxy)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate
C33H40N2O9
HYDROSERPINE PLUS (R-H-H) COMPONENT RESERPINE
VIXO
Hydro-Fluserpine #1
RESERPINE (EP MONOGRAPH)
RESERPINE [EP MONOGRAPH]
l -Carpserp
RESERPINE (USP MONOGRAPH)
Reserpine (USP:INN:BAN:JAN)
RESERPINE [USP MONOGRAPH]
3,5-Trimethoxybenzoyl methyl reserpate
Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-
methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-bis(methyloxy)-18-({[3,4,5-tris(methyloxy)phenyl]carbonyl}oxy)yohimban-16-carboxylate
SMR000059122
Apoplon (TN)
Methylreserpate 3,4,5-trimethoxybenzoic acid
Methyl reserpate 3,5-trimethyloxybenzoic acid
Methyl reserpate 3,5-trimethoxybenzoic acid ester
Methyl reserpate 3,4,5-trimethoxybenzoate (ester)
Methylreserpate 3,4,5-Trimethoxybenzoic acid ester
RCRA waste no. U200
Trichlortensin
Hiposepil
Serathide
Serpazide
Rezide
Reserpine?
Salazide-Demi
Tri-Hydroserpine
WLN: T F6 D5 C666 EM ON&&TTTJ HO1 SOVR CO1 DO1 EO1& TO1 UVO1
CAS-50-55-5
Reserpine,(S)
Serpalan (TN)
(3beta,16beta,17alpha,18beta,20alpha)-11,17-Dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)yohimban-16-carboxylic acid methyl ester
3-.beta., 18-.beta.-hydroxy-11,17-.alpha.-dimethoxy-,methyl ester, 3,4,5-trimethoxybenzoate (ester)
3.beta., 18.beta.-hydroxy-11,17.alpha.-dimethoxy- methyl ester 3,4,5-trimethoxybenzoate (ester)
Benz[g]indolo[2, 1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-3-hydroxy-2,11-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate
METHYL (3beta,16beta,17alpha,18beta,20alpha)-11,17-DIMETHOXY-18-((3,4,5-TRIMETHOXYBENZOYL)OXY)YOHIMBAN-16-CARBOXYLATE
methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-{[(3,4,5-trimethoxyphenyl)carbonyl]oxy}yohimban-16-carboxylate
Yohimban-16-carboxylic acid,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-
Prestwick_147
Reserpine, 99%
Reserpine (Standard)
Spectrum_000109
RESERPINE [INN]
RESERPINE [JAN]
RESERPINE [MI]
79 more names available
RESERPINE [HSDB]
Prestwick0_000875
Prestwick1_000875
Prestwick2_000875
Prestwick3_000875
Spectrum3_000894
Spectrum4_000989
Spectrum5_001415
RESERPINE [VANDF]
RESERPINUM [HPUS]
methyl o-(3,4,5-trimethoxybenzoyl)reserpate
R 0875
RESERPINE [WHO-DD]
RESERPINE [WHO-IP]
SCHEMBL2589
Lopac0_000073
BSPBio_000949
KBioGR_001397
KBioSS_000549
Methyl 18beta-hydroxy-11,17alpha-dimethoxy-3beta,20alpha-yohimban-16beta-carboxylate 3,4,5-trimethoxybenzoate (ester)
methyl dimethoxy-(3,4,5-trimethoxybenzoyl)oxy-[?]carboxylate
MLS002154046
MLS006011754
DivK1c_000012
SPECTRUM1500526
Reserpine - Bio-X trade mark
SPBio_002870
Reserpine (JP18/USP/INN)
BPBio1_001045
GTPL4823
MEGxp0_001904
RESERPINE [ORANGE BOOK]
Yohimban-16-carboxylic acid derivative of benz(g)indolo(2,3-a)quinolizine
ACon1_000086
HMS500A14
HY-N0480R
KBio1_000012
KBio2_000549
KBio2_003117
KBio2_005685
KBio3_001808
C02AA02
NINDS_000012
RESERPINUM [WHO-IP LATIN]
HMS1570P11
HMS1920P04
HMS2092G05
HMS2097P11
HMS2234E24
HMS3260O07
HMS3413D20
HMS3677D20
HMS3714P11
HMS3884I21
Pharmakon1600-01500526
HY-N0480
Reserpine, Vetec(TM) reagent grade
RKL10049
Tox21_111107
Tox21_202395
Tox21_300537
Tox21_500073
BBL028800
BDBM50017712
HB1895
NSC237659
NSC757309
STK801975
RESERPINE COMPONENT OF UNIPRES
AKOS000277559
RESERPINE COMPONENT OF DRALSERP
RESERPINE COMPONENT OF NAQUIVAL
RESERPINE COMPONENT OF REGROTON
Tox21_111107_1
CCG-204168
CS-1913
DB00206
FR09862
KS-5106
LP00073
NSC-757309
RESERPINE COMPONENT OF HYDROPRES
RESERPINE COMPONENT OF RENESE-R
SDCCGSBI-0050061.P005
IDI1_000012
RESERPINE COMPONENT OF CAM-AP-ES
RESERPINE COMPONENT OF HYDRAP-ES
RESERPINE COMPONENT OF METATENSIN
RESERPINE COMPONENT OF SALUTENSIN
RESERPINE COMPONENT OF SER-A-GEN
RESERPINE COMPONENT OF SER-AP-ES
NCGC00091250-01
NCGC00091250-02
NCGC00091250-03
NCGC00091250-05
NCGC00091250-06
NCGC00091250-07
NCGC00091250-08
NCGC00091250-09
NCGC00091250-10
NCGC00091250-12
NCGC00091250-14
NCGC00091250-25
NCGC00254489-01
NCGC00259944-01
NCGC00260758-01
RESERPINE COMPONENT OF H.R.-50
RESERPINE COMPONENT OF HYDROMOX R
(1S,2R,3R,4aS,13bR,14aS)-methyl 2,11-dimethoxy-3-((3,4,5-trimethoxybenzoyl)oxy)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy- methyl ester 3,4,5-trimethoxybenzoate (ester)
AC-13142
AC-34405
BR164333
methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate
methyl 11,17alpha-dimethoxy-18beta-(3,4,5-trimethoxybenzoyloxy)-3beta,20alpha-yohimbane-16beta-carboxylate
NCI60_004446
RESERPINE COMPONENT OF DIUTENSEN-R
RESERPINE COMPONENT OF HYDRO-RESERP
SBI-0050061.P004
RESERPINE COMPONENT OF DEMI-REGROTON
EU-0100073
NS00000355
Reserpine, crystallized, >=99.0% (HPLC)
SW196458-3
UNM000011053801
EN300-84477
RESERPINE COMPONENT OF SERPASIL-ESIDRIX
C06539
D00197
AB01562943_01
RESERPINE COMPONENT OF SERPASIL-APRESOLINE
AE-508/21131019
AJ-160/21107004
Q407841
BRD-K95921201-001-07-0
BRD-K95921201-001-12-0
BRD-K95921201-001-13-8
BRD-K95921201-001-14-6
BRD-K95921201-001-15-3
Methyl reserpate; 3,4,5-Trimethoxybenzoic acid ester
Reserpine, certified reference material, TraceCERT(R)
RESERPINE COMPONENT OF HYDROSERPINE PLUS (R-H-H)
Z1251172867
Reserpine, European Pharmacopoeia (EP) Reference Standard
Reserpine Standard for LC-MS, analytical standard, for LC-MS
Reserpine, United States Pharmacopeia (USP) Reference Standard
Reserpine, Pharmaceutical Secondary Standard; Certified Reference Material
HYDRALAZINE HYDROCHLORIDE-HYDROCHLOROTHIAZIDE-RESERPINE COMPONENT RESERPINE
(1S,2R,3R,4aS,13bR,14aS)-methyl2,11-dimethoxy-3-((3,4,5-trimethoxybenzoyl)oxy)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
(3beta,16beta,17alpha,18beta,20alpha)-11,17-Dimethoxy-18- [(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxyl ic acid methyl ester
200-047-9
3BETA,20ALPHA-YOHIMBAN-16BETA-CARBOXYLIC ACID, 18BETA-HYDROXY-11,17ALPHA-DIMETHOXY-, METHYL ESTER, 3,4,5-TRIMETHOXYBENZOATE
3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-methyl ester 3,4,5-trimethoxybenzoate (ester)
Methyl (3R,16S,17R,18R,20S)-11,17-dimethoxy-18-(3,4,5-trimethoxybenzoyloxy)yohimban-16-carboxylate
methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4(9),5,7-tetraene-19-carboxylate
methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-[(3,4,5-trimethoxyphenyl)carbonyloxy]-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate
METHYL (3.BETA.,16.BETA.,17.ALPHA.,18.BETA.,20.ALPHA.)-11,17-DIMETHOXY-18-((3,4,5-TRIMETHOXYBENZOYL)OXY)YOHIMBAN-16-CARBOXYLATE
methyl (4R)-11,17beta-dimethoxy-18beta-[(3,4,5-trimethoxybenzoyl)oxy]-3beta,20alpha-yohimban-16beta-carboxylate
METHYL 18.BETA.-HYDROXY-11,17.ALPHA.-DIMETHOXY-3.BETA.,20.ALPHA.-YOHIMBAN-16.BETA.-CARBOXYLATE 3,4,5-TRIMETHOXYBENZOATE (ESTER).
METHYL 18beta-HYDROXY-11,17alpha-DIMETHOXY-3beta,20alpha-YOHIMBAN-16beta-CARBOXYLATE 3,4,5-TRIMETHOXYBENZOATE (ESTER).
methyl(1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
YOHIMBAN-16-CARBOXYLIC ACID,11,17-DIMETHOXY-18-((3,4,5-TRIMETHOXYBENZOYL)OXY)-, METHYL ESTER, (3BETA,16BETA,17ALPHA,18BETA,20ALPHA)-
Solubility of Methyl (1R,15S,17R,18R,19S,20S)-6,18-Dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
The solubility of the compound with the chemical formula C45H56N2O10 can be characterized as follows:
In conclusion, the solubility of this compound is likely to be limited in water, making it essential to consider suitable organic solvents for potential applications or extractions. As always, it is recommended to perform empirical testing to determine the solubility in specific environments under controlled conditions.