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Atracurium besylate

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Identification
Molecular formula
C65H82Cl2N2O18
CAS number
64228-81-5
IUPAC name
methyl (1R,2S,4aR,8R)-7-[2-[2-(dimethylamino)ethoxy]-2-oxo-ethylidene]-2-hydroxy-1,4a,8-trimethyl-9-oxo-2,3,4,4b,5,6,8,8a,10,10a-decahydrophenanthrene-1-carboxylate;hydrochloride
State
State

Atracurium besylate is typically solid at room temperature.

Melting point (Celsius)
80.00
Melting point (Kelvin)
353.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
768.09g/mol
Molar mass
768.0870g/mol
Density
1.4300g/cm3
Appearence

Atracurium besylate typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility Profile

The solubility of the compound methyl (1R,2S,4aR,8R)-7-[2-[2-(dimethylamino)ethoxy]-2-oxo-ethylidene]-2-hydroxy-1,4a,8-trimethyl-9-oxo-2,3,4,4b,5,6,8,8a,10,10a-decahydrophenanthrene-1-carboxylate; hydrochloride can be described as follows:

  • Highly Soluble in Water: The presence of a hydrochloride group often enhances the water solubility of organic compounds, making them more favorable for biological applications.
  • Dependency on pH: The solubility can vary significantly with changes in pH, as the ionization of the amine group can promote solvation in more acidic conditions.
  • Organic Solvents: This compound may exhibit varying degrees of solubility in organic solvents such as ethanol or methanol, often influenced by its hydrophobic phenanthrene core.
  • Influence of Molecular Structure: The structural features, including the presence of hydroxyl and dimethylamino groups, are likely to increase hydrogen bonding capabilities, further impacting solubility.

In summary, the complex nature of this compound, coupled with the functional groups present, results in a solubility profile that is markedly influenced by environmental conditions. As one might say, "Understanding solubility is key to harnessing the potential of any chemical compound."

Interesting facts

Interesting Facts about Methyl (1R,2S,4aR,8R)-7-[2-[2-(dimethylamino)ethoxy]-2-oxo-ethylidene]-2-hydroxy-1,4a,8-trimethyl-9-oxo-2,3,4,4b,5,6,8,8a,10,10a-decahydrophenanthrene-1-carboxylate; hydrochloride

This compound, known for its complex structure and numerous applications, is a fascinating example in the realm of organic chemistry. Its intricate arrangement of atoms showcases the beautiful complexity that nature can produce:

  • Biological Activity: Compounds similar to this one have been studied extensively for their potential pharmacological properties. Some derivatives are known to exhibit properties that can be beneficial in medical research.
  • Synthetic Routes: The synthesis of this compound often involves multiple steps, incorporating various functional groups which are strategically added to develop the desired characteristics, making it a fun challenge for organic chemists!
  • Dimensional Analysis: The stereochemical aspects of the compound (1R,2S,4aR,8R) highlight the importance of chirality in organic compounds, particularly in the pharmaceutical industry where the orientation of atoms can significantly affect biological activity.
  • Applications: While its full potential is ongoing to be studied, this compound can serve as a precursor or scaffold in the synthesis of more complex drugs, bridging the gap between simple compounds and more active pharmaceutical ingredients.

As stated by renowned chemist Robert H. Grubbs, “Chemistry is not just about molecules, it’s about the stories they tell.” The story of this compound is still unfolding, and it represents the rigorous pursuit of knowledge in the field of chemical science.

In conclusion, exploring compounds like this is crucial for both synthetic methodologies and biological pharmacology, making it an engaging area of study for chemists worldwide.