Skip to main content

Atropine

ADVERTISEMENT
Identification
Molecular formula
C17H23NO3
CAS number
51-55-8
IUPAC name
methyl (1S,9S)-13-ethylidene-18-(hydroxymethyl)-15-methyl-8-aza-15-azoniapentacyclo[10.5.1.01,9.02,7.09,15]octadeca-2,4,6-triene-18-carboxylate
State
State

At room temperature, atropine is generally found in a solid state as it is usually handled in its crystalline form.

Melting point (Celsius)
118.00
Melting point (Kelvin)
391.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
289.37g/mol
Molar mass
289.3690g/mol
Density
1.3300g/cm3
Appearence

Atropine is typically found in the form of crystalline powder or granules. It is white to off-white in color and is odorless. When prepared in its sulfate salt form, it may exhibit slight moisture absorption properties.

Comment on solubility

Solubility of Methyl (1S,9S)-13-ethylidene-18-(hydroxymethyl)-15-methyl-8-aza-15-azoniapentacyclo[10.5.1.01,9.02,7.09,15]octadeca-2,4,6-triene-18-carboxylate

The solubility characteristics of methyl (1S,9S)-13-ethylidene-18-(hydroxymethyl)-15-methyl-8-aza-15-azoniapentacyclo[10.5.1.01,9.02,7.09,15]octadeca-2,4,6-triene-18-carboxylate can be quite intriguing due to its complex structure. Generally, the solubility of such compounds depends on several factors, including:

  • Polarity: The presence of hydroxymethyl and carboxylate groups tends to increase polarity, enhancing solubility in polar solvents like water.
  • Hydrophobic parts: The pentacyclic structure may introduce hydrophobic characteristics, which can limit solubility in aqueous environments.
  • Concentration: As with many compounds, solubility may vary with concentration, where higher or lower concentrations could lead to different solubility behaviors.

"Like dissolves like," a common phrase in chemistry, applies here — meaning organic solvents might be more effective at dissolving this compound than polar solvents, despite the presence of polar groups. Thus, when considering practical applications or reactions, assessing the compatibility of solvents is crucial.

In summary, while there are enhancing factors for solubility due to certain functional groups, the overall complex structure suggests a nuanced solubility profile that is worthy of experimental verification for precise applications.

Interesting facts

Interesting Facts about Methyl (1S,9S)-13-ethylidene-18-(hydroxymethyl)-15-methyl-8-aza-15-azoniapentacyclo[10.5.1.01,9.02,7.09,15]octadeca-2,4,6-triene-18-carboxylate

This complex organic compound is a wonderful example of structural diversity in chemical compounds, particularly in the realm of natural product chemistry. Here are some fascinating details about this compound:

  • Chemical Structure: The name indicates an intricate structure featuring five fused rings, which can be categorized as a pentacyclic structure. Such complexity often relates to high biological activity, making it appealing for research in medicinal chemistry.
  • Biological Significance: Compounds with similar fused ring systems are often found in nature, particularly in alkaloids and other biological molecules. Many exhibit significant physiological effects, which motivates scientists to investigate their potential pharmacological applications.
  • Functional Groups: The presence of both carboxylate and hydroxymethyl groups in this compound hints at interesting reactivity. These groups can serve as sites for chemical modification or be responsible for interactions with biological macromolecules.
  • Role in Research: Due to its structural complexity, compounds like this one are frequently used as lead structures in drug discovery. Chemists often explore modifications to enhance efficacy while minimizing toxicity.
  • Chirality: The presence of stereocenters (1S, 9S) indicates that this molecule is chiral, which is critical in biochemistry. Chirality can influence how a drug behaves in a biological system, leading to differences in efficacy and safety.

In conclusion, methyl (1S,9S)-13-ethylidene-18-(hydroxymethyl)-15-methyl-8-aza-15-azoniapentacyclo[10.5.1.01,9.02,7.09,15]octadeca-2,4,6-triene-18-carboxylate is more than just a chemical formula; it represents a wealth of potential avenues for research and application. As scientists continue to unlock the secrets held within similar compounds, there is much excitement surrounding their role in advancing healthcare and our understanding of biochemistry.