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methyl 2-[(2-fluoroacetyl)-(1-naphthyl)amino]acetate

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Identification
Molecular formula
C15H14FNO3
CAS number
NA
IUPAC name
methyl 2-[(2-fluoroacetyl)-(1-naphthyl)amino]acetate
State
State

At room temperature, this compound exists in a solid state. Its crystalline form is stable under standard conditions, allowing for easy handling and manipulation in laboratory settings.

Melting point (Celsius)
103.50
Melting point (Kelvin)
376.65
Boiling point (Celsius)
411.30
Boiling point (Kelvin)
684.45
General information
Molecular weight
291.28g/mol
Molar mass
291.2820g/mol
Density
1.2100g/cm3
Appearence

This compound typically manifests as a crystalline solid. Its color can range from white to off-white, indicating some level of purity and potential impurities within the sample. The compound does not usually emit any notable odor.

Comment on solubility

Solubility of Methyl 2-[(2-fluoroacetyl)-(1-naphthyl)amino]acetate

Methyl 2-[(2-fluoroacetyl)-(1-naphthyl)amino]acetate is a complex organic compound whose solubility is highly influenced by its chemical structure. The solubility of this compound can be characterized by several key aspects:

  • Polarity: The presence of polar functional groups such as the acetyl and amino functionalities often contributes to increased solubility in polar solvents like water.
  • Hydrogen Bonding: The amino group within the compound can participate in hydrogen bonding, which enhances its interactions with polar solvents, potentially improving solubility.
  • Hydrophobic Effects: Conversely, the naphthalene moiety presents more hydrophobic characteristics, which may limit solubility in aqueous environments.
  • Solvent Compatibility: This compound tends to be more soluble in organic solvents such as ethanol and DMSO, where both polar and non-polar characteristics can be effectively accommodated.

Throughout studies, it has been observed that the solubility of such compounds is not absolute and can vary significantly based on the specific solvent conditions, temperature, and concentration. In summary, while the solubility of methyl 2-[(2-fluoroacetyl)-(1-naphthyl)amino]acetate in water may be limited due to its hydrophobic characteristics, it shows favorable solubility in many organic solvents due to the polar functionalities present in its molecular structure.

Interesting facts

Interesting Facts about Methyl 2-[(2-Fluoroacetyl)-(1-Naphthyl)amino]acetate

Methyl 2-[(2-fluoroacetyl)-(1-naphthyl)amino]acetate is a fascinating compound that combines several intriguing elements of organic chemistry. Here are some insights and unique characteristics:

  • Structural Diversity: This compound is notable for its complex structure, featuring both a naphthyl group and a fluoroacetyl unit. The integration of these distinct functional groups allows for a wide range of reactivity and potential applications.
  • Biological Relevance: Compounds like this one often play significant roles in medicinal chemistry. The presence of the fluoroacetyl moiety can influence biological activity, making it a subject of interest for drug design and development.
  • Fluorine's Influence: The introduction of fluorine into organic molecules, such as in this compound, can enhance their metabolic stability and lipophilicity, which are crucial factors in the pharmacokinetics of drug compounds.
  • Potential Applications: Given its structure, methyl 2-[(2-fluoroacetyl)-(1-naphthyl)amino]acetate may be evaluated for its use in synthesizing more complex molecules or as a starting material in the development of new pharmaceuticals.
  • Research Interest: Synthetic organic chemists may find this compound to be particularly interesting for studying reaction methodologies, such as nucleophilic substitutions or coupling reactions, highlighting its importance in the academic realm.

In summary, methyl 2-[(2-fluoroacetyl)-(1-naphthyl)amino]acetate exemplifies how a single compound can encapsulate the rich interplay of structure, reactivity, and functionality that defines much of modern organic chemistry. As chemists continue to explore its behaviors and uses, we expand our understanding of both fundamental and applied science.

Synonyms
23554-61-2
BRN 2148189
GLYCINE, N-(FLUOROACETYL)-N-1-NAPHTHYL-, METHYL ESTER
N-(Fluoroacetyl)-N-1-naphthylglycine methyl ester
DTXSID70178144
RefChem:346519
DTXCID00100635