Skip to main content

Methyl 2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate

ADVERTISEMENT
Identification
Molecular formula
C17H14N2O3
CAS number
87971-62-4
IUPAC name
methyl 2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate
State
State

At room temperature, methyl 2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate is in a solid state.

Melting point (Celsius)
209.40
Melting point (Kelvin)
482.55
Boiling point (Celsius)
327.20
Boiling point (Kelvin)
600.35
General information
Molecular weight
292.31g/mol
Molar mass
292.3050g/mol
Density
1.3110g/cm3
Appearence

Methyl 2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate typically appears as a solid at room temperature. The compound may be crystalline in form and can vary in color ranging from white to off-white.

Comment on solubility

Solubility of Methyl 2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate

Methyl 2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate is a compound with intriguing solubility characteristics. Understanding its solubility can inform its biological activity and application in various fields. Here are some key points regarding this compound's solubility:

  • Solvent interactions: This compound is likely to exhibit varying solubility in different solvents due to the presence of both hydrophobic (aromatic and aliphatic) and polar functional groups.
  • Polar solvents: Methyl 2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate may show enhanced solubility in polar solvents like methanol and ethanol due to potential hydrogen bonding interactions.
  • Non-polar solvents: Conversely, its solubility could decrease in non-polar solvents such as hexane or chloroform, where the hydrophobic portions dominate.
  • Temperature effects: Like many organic compounds, solubility may also increase with temperature, making it more soluble in warm solvents.

In summary, while the specific solubility of methyl 2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate is not universally defined, its varying solubility across different solvents emphasizes the need for experimental determination. Understanding the solubility behavior of this compound is essential for its proper application in chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about Methyl 2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate

Methyl 2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate is a fascinating compound that lies at the intersection of organic chemistry and medicinal research. Here are some noteworthy points about this intriguing molecule:

  • Quinazoline Derivative: This compound is a derivative of quinazoline, a bicyclic compound that has garnered considerable attention due to its diverse biological activities, including anti-cancer and anti-inflammatory properties.
  • Synthetic Potential: The synthetic route to obtain this compound can lead to several other derivatives, highlighting its versatility in chemical synthesis. Researchers often explore methods to modify its structure for enhanced bioactivity.
  • Biological Activity: Molecules in this class are often investigated for their potential pharmacological applications. Studies have indicated that various quinazoline derivatives exhibit properties such as:
    • Anti-tumor effects
    • Antimicrobial activities
    • Inhibition of certain enzymes that play roles in disease processes
  • Importance in Drug Discovery: Compounds like methyl 2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate are often used as lead compounds in the development of new therapeutics. Their ability to modulate biological pathways makes them crucial in pharmaceutical research.
  • Structure-Activity Relationship (SAR): Studying the structure-activity relationships of quinazoline derivatives, including this compound, helps chemists understand how slight modifications can substantially affect their efficacy and safety profiles. Such research can lead to the identification of compounds with enhanced therapeutic benefits and reduced side effects.

In conclusion, methyl 2-(2-methyl-4-oxo-quinazolin-3-yl)benzoate represents a small but significant piece in the puzzle of drug discovery and development, paving the way for future innovations in medicinal chemistry. Scientists continue to explore its potential, hoping to unlock new therapeutic avenues.

Synonyms
B 270
2006-80-6
BRN 0282830
BENZOIC ACID, o-(2-METHYL-3-(4(3H)-QUINAZOLINONYL)), METHYL ESTER
Methyl o-(2-methyl-3-(4(3H)-quinazolinonyl))benzoate
2-Methyl-3-(2'-methoxycarbonylphenyl)chinazolinone-(4) [German]
DTXSID50173874
5-24-03-00157 (Beilstein Handbook Reference)
2-Methyl-3-(2'-methoxycarbonylphenyl)chinazolinone-(4)
DTXCID9096365
methyl 2-(2-methyl-4-oxoquinazolin-3-yl)benzoate
MLS000062064
methyl 2-(2-methyl-4-oxo-3(4H)-quinazolinyl)benzoate
SMR000070060
METHYL 2-[2-METHYL-4-OXO-3(4H)-QUINAZOLINYL]BENZOATE
Oprea1_483698
Oprea1_658028
cid_16175
CHEMBL1608226
BDBM56167
HMS2302O08
STL553602
AKOS000661384
AB00093084-01
AB00093084-11
BRD-K55306531-001-06-5
methyl 2-(2-methyl-4-oxoquinazolin-3(4H)-yl)benzoate
2-(2-methyl-4-oxo-3-quinazolinyl)benzoic acid methyl ester
2-(4-keto-2-methyl-quinazolin-3-yl)benzoic acid methyl ester
methyl 2-(2-methyl-4-oxidanylidene-quinazolin-3-yl)benzoate