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Methyl 2-(3-fluoro-4-phenylphenyl)propanoate

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Identification
Molecular formula
C16H15FO2
CAS number
327-74-2
IUPAC name
methyl 2-(3-fluoro-4-phenyl-phenyl)propanoate
State
State

At room temperature, Methyl 2-(3-fluoro-4-phenylphenyl)propanoate is generally found in a liquid state, although it may solidify as a viscous substance depending on the specific conditions and purity.

Melting point (Celsius)
25.00
Melting point (Kelvin)
298.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
244.27g/mol
Molar mass
244.2680g/mol
Density
1.1000g/cm3
Appearence

Methyl 2-(3-fluoro-4-phenylphenyl)propanoate typically appears as a colorless to pale yellow liquid or viscous solid. It may have a faint aromatic odor depending on its purity and specific formulation.

Comment on solubility

Solubility of Methyl 2-(3-fluoro-4-phenyl-phenyl)propanoate (C16H15FO2)

Methyl 2-(3-fluoro-4-phenyl-phenyl)propanoate exhibits a notable profile in terms of solubility, which can be influenced by various factors including its molecular structure and polarity.

Key Points about Solubility:

  • Polarity: The presence of the fluoro group can increase the polarity of the compound, enhancing its solubility in polar solvents.
  • Solvent Compatibility: Methyl 2-(3-fluoro-4-phenyl-phenyl)propanoate is expected to be soluble in organic solvents such as ethanol, methanol, and acetone due to its non-polar phenyl segments.
  • Water Solubility: Given its organic nature and specific structure, its solubility in water is likely low.
  • Temperature Influence: Generally, increased temperatures can lead to improved solubility for organic compounds.

As a rule of thumb, the solubility can vary significantly based on the choice of solvent and environmental conditions. Therefore, when considering methyl 2-(3-fluoro-4-phenyl-phenyl)propanoate, conducting experimental solubility tests in various solvents would provide further insights into its behavior in specific contexts.

Interesting facts

Interesting Facts about Methyl 2-(3-Fluoro-4-phenyl-phenyl)propanoate

Methyl 2-(3-fluoro-4-phenyl-phenyl)propanoate is a compound that showcases the intriguing interplay of fluorine in organic chemistry. Here are some noteworthy aspects of this compound:

  • Fluorination Effects: The introduction of a fluorine atom into the molecular structure can significantly alter the compound's properties, including its reactivity and biological activity. Fluorine is known for enhancing metabolic stability in drug molecules.
  • Versatile Applications: Due to its unique structure, this compound may have potential applications in medicinal chemistry. It could serve as a scaffold for designing new pharmaceuticals, especially in targeting receptor sites due to the phenyl groups that can facilitate interactions within biological systems.
  • Synthesis: The synthesis of methyl 2-(3-fluoro-4-phenyl-phenyl)propanoate can be an exciting challenge for organic chemists. The incorporation of the fluorine substituent typically requires specific methodologies, often involving fluorinated reagents or catalysts.
  • Phenyl-Phenyl Interactions: The presence of two phenyl rings suggests that this compound may exhibit interesting *π-π stacking interactions*, which are vital in materials science and biological systems, particularly in the design of organic semiconductors and drug formulations.
  • Research Potential: This compound can be a starting point for further research aimed at exploring its interactions with various biological targets. Chemical compounds with similar structures are frequently investigated for their anticancer, anti-inflammatory, and other pharmacological properties.

In conclusion, methyl 2-(3-fluoro-4-phenyl-phenyl)propanoate is more than just a chemical entity; it represents a nexus of chemistry and biology that embodies the ongoing quest for innovative solutions in drug discovery and material science.

Synonyms
Flurbiprofen methyl ester
66202-86-6
methyl flurbiprofen
[1,1'-Biphenyl]-4-acetic acid, 2-fluoro-a-methyl-, methyl ester
methyl 2-(3-fluoro-4-phenylphenyl)propanoate
MethylFlurbiprofen-d3
CHEMBL162300
DTXSID50274416
METHYL 2-(2-FLUORO-BIPHENYL-4-YL)-PROPIONATE
methyl 2-(2-fluoro-biphenyl-4yl)propionate
Febuxostat 2-Butyl Isomer
Methyl 2-(2-fluoro-[1,1'-biphenyl]-4-yl)propanoate
Methyl 2-(2-fluoro[1,1'-biphenyl]-4-yl)propanoate
methyl 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoate
2-(2-Fluoro-biphenyl-4-yl)-propionic acid methyl ester
methyl 2-(2-fluorobiphenyl-4-yl)propanoate
Flurbiprofen methyl ester; Methyl flurbiprofen; 2-Fluoro-alpha-methyl-[1,1'-biphenyl]-4-acetic acid methyl ester; (+/-)-Flubiprofen methyl ester
SCHEMBL1543413
SCHEMBL13448835
(+/-)-Flubiprofen methyl ester
DTXCID80225895
(+/-)-Flurbiprofen methyl ester
55VME83H96
Flubiprofen methyl ester, (+/-)-
BDBM50139246
MFCD00871005
AKOS016035422
BS-18953
SY348885
methyl 2-(2-fluoro-4-biphenylyl)propionate
Methyl 2-(2-Fluoro-4-biphenylyl)propanoate
G78329
methyl (2S)-2-(3-fluoro-4-phenylphenyl)propanoate
Methyl2-(2-fluoro-[1,1'-biphenyl]-4-yl)propanoate
Methyl 2-(2-fluoro[1,1'-biphenyl]-4-yl)propanoate #
Methyl 2-fluoro-alpha-methyl[1,1'-biphenyl]-4-acetate
[1,1'-Biphenyl]-4-acetic acid, 2-fluoro-alpha-methyl-, methyl ester
889-721-7