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Methyl 2-(4-aminophenyl)-1-oxo-7-(2-pyridylmethoxy)-4-(3,4,5-trimethoxyphenyl)isoquinoline-3-carboxylate

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Identification
Molecular formula
C30H27N3O7
CAS number
435341-71-4
IUPAC name
methyl 2-(4-aminophenyl)-1-oxo-7-(2-pyridylmethoxy)-4-(3,4,5-trimethoxyphenyl)isoquinoline-3-carboxylate
State
State

At room temperature, methyl 2-(4-aminophenyl)-1-oxo-7-(2-pyridylmethoxy)-4-(3,4,5-trimethoxyphenyl)isoquinoline-3-carboxylate exists as a solid crystalline powder. It is relatively stable under normal conditions.

Melting point (Celsius)
259.00
Melting point (Kelvin)
532.15
Boiling point (Celsius)
634.00
Boiling point (Kelvin)
907.15
General information
Molecular weight
552.56g/mol
Molar mass
552.5620g/mol
Density
1.3700g/cm3
Appearence

The compound is typically a light yellow to off-white crystalline powder. It is not known to have any distinctive odor.

Comment on solubility

Solubility of Methyl 2-(4-aminophenyl)-1-oxo-7-(2-pyridylmethoxy)-4-(3,4,5-trimethoxyphenyl)isoquinoline-3-carboxylate

The solubility characteristics of methyl 2-(4-aminophenyl)-1-oxo-7-(2-pyridylmethoxy)-4-(3,4,5-trimethoxyphenyl)isoquinoline-3-carboxylate (C30H27N3O7) can be intriguing due to its complex structure. Here are several key points regarding its solubility:

  • Polar and Non-Polar Interaction: The presence of various functional groups, such as amino and methoxy groups, can affect the solubility in polar solvents like water.
  • Solubility in Organic Solvents: This compound is more likely to dissolve in non-polar organic solvents due to its large hydrophobic isoquinoline structure.
  • Temperature Dependence: Like many organic compounds, its solubility can vary with temperature; generally, increasing temperature tends to increase solubility.
  • pH Sensitivity: The solubility may also be influenced by the pH of the solution, altering the ionization state of the amino groups which can enhance solubility in alkaline conditions.

In conclusion, understanding the solubility of such a versatile compound requires consideration of various factors including solvent polarity, temperature, and pH. Each aspect plays a vital role in determining how this compound behaves in different environments, making it a fascinating subject for further study.

Interesting facts

Interesting Facts about Methyl 2-(4-Aminophenyl)-1-oxo-7-(2-pyridylmethoxy)-4-(3,4,5-trimethoxyphenyl)isoquinoline-3-carboxylate

This compound, known for its intricate structure, belongs to a class of molecules that has garnered great attention in medicinal chemistry. Its chemical composition suggests the following key points:

  • Diverse Applications: The presence of the isoquinoline core in its structure is associated with a myriad of biological activities, making it a promising candidate for drug development.
  • Potential Therapeutic Benefits: Compounds similar to this one have shown potential in areas such as anticancer and anti-inflammatory research. They may play a role in inhibiting cell proliferation in various cancer models.
  • Structural Complexity: The intricate assembly of functional groups, including methoxy and amino substituents, allows for diverse interactions with biological targets. This structural complexity can lead to enhanced pharmacological properties.
  • Research Interest: The unique molecular design represents an area of active research, with studies often focusing on its synthesis and optimization for better efficacy and reduced toxicity.
  • Mechanistic Insights: Understanding the mechanisms by which such compounds exert their effects at the molecular level is vital for harnessing their therapeutic potential. This includes evaluating how they impact signal transduction pathways in cells.

As scientists continue to explore this compound, there is hope that its intricate structure will pave the way for new discoveries in medicinal chemistry. As one researcher aptly put it, "Every new compound is a story yet to be told, and this one is no exception."

In conclusion, methyl 2-(4-aminophenyl)-1-oxo-7-(2-pyridylmethoxy)-4-(3,4,5-trimethoxyphenyl)isoquinoline-3-carboxylate exemplifies the intrigue and promise of synthetic organic compounds in the quest for new therapeutic agents.

Synonyms
T-1032 free base
GNI5R14CFD
UNII-GNI5R14CFD
212500-02-2
3-Isoquinolinecarboxylic acid, 2-(4-aminophenyl)-1,2-dihydro-1-oxo-7-(2-pyridinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-, methyl ester
CHEMBL553371
NCGC00016052-01
Lopac-T-7692
Lopac0_001241
SCHEMBL687427
CHEMBL1179483
BDBM50100662
CCG-205315
NCGC00016052-02
NCGC00162374-01
Q27279196
methyl 2-(4-aminophenyl)-1-oxo-7-(2-pyridylmethoxy)-4-(3,4,5-trimethoxyphenyl)-1,2-dihydro-3-isoquinolinecarboxylate.dihydrochloride
T-5