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Methyl 2-(aziridin-1-yl)acetate

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Identification
Molecular formula
C5H9NO2
CAS number
1753-39-1
IUPAC name
methyl 2-(aziridin-1-yl)acetate
State
State

At room temperature, methyl 2-(aziridin-1-yl)acetate exists as a liquid. It is usually handled in liquid form for various chemical applications.

Melting point (Celsius)
-56.00
Melting point (Kelvin)
217.15
Boiling point (Celsius)
166.00
Boiling point (Kelvin)
439.15
General information
Molecular weight
129.15g/mol
Molar mass
129.1520g/mol
Density
1.0600g/cm3
Appearence

Methyl 2-(aziridin-1-yl)acetate is a clear liquid at room temperature. It is typically colorless, though it might appear slightly yellow if impure.

Comment on solubility

Solubility of Methyl 2-(aziridin-1-yl)acetate

Methyl 2-(aziridin-1-yl)acetate is a unique compound that exhibits moderate solubility characteristics. The solubility of such compounds can often be influenced by various factors:

  • Polarity: As a derivative of aziridine, the presence of both ester and amine functionalities contributes to its overall polarity. This affects its solubility in both polar and non-polar solvents.
  • Hydrogen Bonding: The ability of methyl 2-(aziridin-1-yl)acetate to engage in hydrogen bonding can enhance its solubility in polar solvents such as water and alcohols.
  • Temperature: Like many organic compounds, an increase in temperature typically increases solubility, thereby allowing it to dissolve more readily in various solvents.

In practice, methyl 2-(aziridin-1-yl)acetate is expected to be soluble in common organic solvents such as ethanol and acetone, while demonstrating limited solubility in non-polar solvents like hexane. This solubility behavior can be summarized as:

  • Slightly soluble: In non-polar solvents (e.g., hexane)
  • Soluble: In polar solvents (e.g., ethanol, acetone)

Understanding the solubility properties of methyl 2-(aziridin-1-yl)acetate is fundamental for its application in various chemical processes, including synthesis and formulation developments. Such solubility insights enhance its utility in research and industrial applications alike.

Interesting facts

Interesting Facts about Methyl 2-(aziridin-1-yl)acetate

Methyl 2-(aziridin-1-yl)acetate is a compound that offers fascinating insights into the field of organic chemistry. This compound features an intriguing aziridine ring, which is a three-membered nitrogen-containing heterocycle. Here are some interesting aspects of this compound:

  • Unique Structure: The presence of the aziridine ring contributes to its reactivity and is an essential feature in various synthetic pathways.
  • Applications in Synthesis: Methyl 2-(aziridin-1-yl)acetate is often used as a building block in organic synthesis, especially in the production of biologically active compounds.
  • Biological Activity: Compounds containing aziridine rings, like methyl 2-(aziridin-1-yl)acetate, have been linked to interesting biological activities, including potential anti-cancer properties.
  • Versatility: This compound can also be utilized in the development of various pharmaceuticals, contributing to the advancement of medicinal chemistry.
  • Reactivity: Aziridines are known for their ability to undergo ring-opening reactions, which can lead to a wide variety of derivatives with diverse functionalities.

As you delve deeper into the chemistry of methyl 2-(aziridin-1-yl)acetate, you'll uncover the potential it holds not just in theoretical studies but also in practical applications that push the boundaries of chemical research. “Chemistry isn't just about substances, but about transformations!” This transforms the understanding of how small molecules can lead to significant impacts in various fields.

Synonyms
1-(Carbomethoxymethyl)aziridine
14745-52-9
Methyl 1-aziridineacetate
1-(Methoxycarbonyl)aziridine
N-(Carbomethoxymethyl)aziridine
1-AZIRIDINEACETIC ACID, METHYL ESTER
NSC 101284
SK 4119
BRN 0110304
2-(1-Aziridinyl)acetic acid methyl ester
Acetic acid, 2-(1-aziridinyl)-, methyl ester
DTXSID60163721
4-20-00-00023 (Beilstein Handbook Reference)
DTXCID0086212
methyl 2-(aziridin-1-yl)acetate
1-Aziridineacetic acid methyl ester
NCIOpen2_001711
SCHEMBL1133592
NSC101284
NSC-101284