Skip to main content

Methyl 2-chloro-5-nitrobenzoate

ADVERTISEMENT
Identification
Molecular formula
C8H6ClNO4
CAS number
30453-66-2
IUPAC name
methyl 2-chloro-5-nitro-benzoate
State
State

Methyl 2-chloro-5-nitrobenzoate is in a solid state at room temperature. It is typically stable under standard laboratory conditions but should be stored away from extreme conditions to maintain its structural integrity.

Melting point (Celsius)
67.00
Melting point (Kelvin)
340.15
Boiling point (Celsius)
333.90
Boiling point (Kelvin)
607.05
General information
Molecular weight
229.59g/mol
Molar mass
229.5870g/mol
Density
1.4010g/cm3
Appearence

Methyl 2-chloro-5-nitrobenzoate is a crystalline compound that typically appears as a yellowish solid. It can be found in a solid state under standard conditions, and the crystals are often small and can vary in hue from light yellow to a more pronounced yellow, depending on the level of purity and the specific conditions of crystallization.

Comment on solubility

Solubility of Methyl 2-chloro-5-nitro-benzoate

Methyl 2-chloro-5-nitro-benzoate is a compound with interesting solubility characteristics influenced by its molecular structure. Understanding its solubility can be key for applications ranging from synthesis to formulation.

Solubility Characteristics

  • Polar vs Non-Polar: The presence of the nitro group (-NO2) and chlorine atom (-Cl) makes this compound relatively polar. Thus, it is more soluble in polar solvents than in non-polar ones.
  • Common Solvents: Methyl 2-chloro-5-nitro-benzoate tends to dissolve well in solvents such as:
    • Ethyl acetate
    • Methanol
    • Aqueous solutions under certain conditions
  • Solubility Limits: While it may dissolve in polar solvents, its solubility is limited in non-polar solvents (e.g., hexane). This is due to the inherent molecular interactions that do not favor solvation in such environments.
  • Temperature Effects: Like many organic compounds, the solubility of methyl 2-chloro-5-nitro-benzoate may increase with temperature. This means that warm solvents can potentially dissolve more of this compound compared to cold solvents.

In summary, the solubility of methyl 2-chloro-5-nitro-benzoate is driven by its molecular polarity and functional groups. When considering this compound for practical applications, selecting an appropriate solvent can significantly impact its effectiveness.

Interesting facts

Interesting Facts about Methyl 2-Chloro-5-Nitro-Benzoate

Methyl 2-chloro-5-nitro-benzoate is a fascinating compound with several unique attributes that spark interest within the realm of organic chemistry. Here are some enlightening points about this compound:

  • Versatile Intermediate: This compound serves as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, making it a valuable component in both medicinal chemistry and agricultural applications.
  • Functional Group Diversity: Methyl 2-chloro-5-nitro-benzoate exhibits multiple functional groups, including the chloro and nitro substituents. These functionalities can significantly influence the compound's reactivity and properties.
  • Electrophilic Reactions: Due to the presence of the electron-withdrawing nitro group, methyl 2-chloro-5-nitro-benzoate is more susceptible to electrophilic substitution reactions, which opens up avenues for further chemical transformations.
  • Applications in Synthesis: This compound can be utilized to create more complex molecules through various synthetic routes, such as nucleophilic substitution and coupling reactions, making it highly relevant in research settings.
  • Chirality Considerations: The incorporation of a methyl group and the chlorinated site can lead to chiral centers if further transformation occurs, leading to the potential development of enantiomerically pure substances.
  • Environmental Perspective: Understanding compounds like methyl 2-chloro-5-nitro-benzoate is essential for evaluating their environmental impact, particularly in terms of degradation pathways and toxicity.

In summary, methyl 2-chloro-5-nitro-benzoate is not just a compound to study but a potential gateway to understanding broader chemical principles and applications. The interplay of functional groups and their effects on reactivity make it a subject of interest in both academic and industrial chemistry.

Synonyms
Methyl 2-chloro-5-nitrobenzoate
6307-82-0
613-139-2
2-Chloro-5-nitrobenzoic acid methyl ester
BENZOIC ACID, 2-CHLORO-5-NITRO-, METHYL ESTER
MFCD00184587
2-chloro-5-nitro-benzoic acid methyl ester
NSC-44287
Methyl 2-chloro-5-nitrobenzenecarboxylate
BRN 1966320
Methyl2-Chloro-5-nitrobenzoate
Methylester kyseliny 2-chlor-5-nitrobenzoove
Methylester kyseliny 2-chlor-5-nitrobenzoove [Czech]
L7RN5S2SA7
4-09-00-01228 (Beilstein Handbook Reference)
SCHEMBL422653
CHEMBL2260451
DTXSID90212397
NSC44287
NSC 44287
STK361847
AKOS000283610
CS-W014889
UPCMLD0ENAT5948501:001
SY007297
2-chloro-1-methoxycarbonyl-5-nitrobenzene
2-Chloro-5-nitrobenzoic acid, methyl ester
DB-054402
C1732
NS00035284
EN300-28646
6W-0299
Q63395371
Z19718166