methyl 2-cyano-3-(5-nitro-2-furyl)acrylate

Identification

Molecular formula

C₉H₆N₂O₅

CAS number

13947-59-8

IUPAC name

methyl 2-cyano-3-(5-nitro-2-furyl)prop-2-enoate

State

The compound is typically found in a solid state at room temperature.

Melting point (Celsius)

160.00

Melting point (Kelvin)

433.15

Boiling point (Celsius)

298.00

Boiling point (Kelvin)

571.15

General information

Molecular weight

222.16g/mol

Molar mass

222.1680g/mol

Density

1.4073g/cm³

Appearence

The compound appears as a yellow crystalline solid. It is often used in the synthesis of other chemical substances due to its reactive functional groups, primarily for its potent conjugative properties.

Comment on solubility

Solubility of Methyl 2-Cyano-3-(5-nitro-2-furyl)prop-2-enoate

Methyl 2-cyano-3-(5-nitro-2-furyl)prop-2-enoate is an intriguing compound that presents unique solubility characteristics due to its structure. Analyzing solubility can be a complex affair influenced by several factors:

Polarity: The presence of cyano and nitro groups contributes to the overall polarity of the molecule, which can enhance its solubility in polar solvents.
Hydrogen Bonding: The nitro group can engage in hydrogen bonding, potentially increasing solubility in protic solvents like water.
Hydrophobic Interactions: The furyl portion may introduce some hydrophobic interactions, suggesting limited solubility in non-polar solvents.

It is important to consider specific solvent interactions that may influence solubility as well. For example:

In Water: The solubility may vary; it is likely to be moderate due to competing interactions.
In Organic Solvents: It could show higher solubility in organic solvents such as ethanol or acetone, which can accept hydrogen bonds.

In conclusion, while the intricate balance of polar and non-polar characteristics influences the solubility of methyl 2-cyano-3-(5-nitro-2-furyl)prop-2-enoate, it remains essential to conduct empirical studies to confirm solubility behavior in various solvents. Exploring solubility not only helps in understanding the compound but also assists in predicting its behavior in chemical reactions and applications.

Interesting facts

Interesting Facts about Methyl 2-cyano-3-(5-nitro-2-furyl)prop-2-enoate

Methyl 2-cyano-3-(5-nitro-2-furyl)prop-2-enoate is a fascinating compound that has garnered attention in both organic chemistry and pharmacology. Here are some intriguing points about this compound:

Unique Structure: The compound features a cyano group and a nitro substituted furan ring, which can enhance its reactivity and potential biological activity.
Reactivity: The presence of both a cyano and an alkene group in the molecule allows it to participate in various chemical reactions, such as nucleophilic additions and cycloadditions, making it a valuable intermediate in synthetic chemistry.
Pharmacological Potential: Compounds with nitro and cyano groups have been researched for their potential use in pharmaceuticals, particularly in the development of anti-cancer agents or antimicrobials, owing to their unique interactions with biological systems.
Synthesis: The synthesis of this compound often involves multi-step reactions, which can include condensation and functional group modifications, illustrating the creativity required in organic synthesis.
Research Interest: The presence of a furan ring, known for its aromatic properties, can lead to interesting metabolic pathways in biological systems, making this compound an interesting subject for research.

As scientists continue to explore the properties and reactivity of methyl 2-cyano-3-(5-nitro-2-furyl)prop-2-enoate, it stands as a testament to the complexity and beauty of organic compounds. Its structure not only hints at a myriad of chemical possibilities but also at a wealth of untapped therapeutic potentials.

Synonyms

2-Methoxycarbonyl-3-(5-nitro-2-furyl)acrylonitrile

methyl (2Z)-2-cyano-3-(5-nitrofuran-2-yl)prop-2-enoate

methyl 2-cyano-3-(5-nitrofuran-2-yl)prop-2-enoate

DTXSID401033701