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Methyl 2-nitroacetate

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Identification
Molecular formula
C4H7NO4
CAS number
4645-42-7
IUPAC name
methyl 2-nitroacetate
State
State

Methyl 2-nitroacetate is typically found as a liquid at room temperature due to its relatively low melting point.

Melting point (Celsius)
-51.00
Melting point (Kelvin)
222.15
Boiling point (Celsius)
128.00
Boiling point (Kelvin)
401.15
General information
Molecular weight
133.08g/mol
Molar mass
133.0780g/mol
Density
1.2964g/cm3
Appearence

Methyl 2-nitroacetate is a colorless to light yellow liquid. This compound is commonly used as an intermediate for chemical syntheses and exhibits a variety of properties due to the presence of both ester and nitro functional groups.

Comment on solubility

Solubility of Methyl 2-nitroacetate

Methyl 2-nitroacetate, a compound with the chemical formula C3H5NO4, exhibits interesting solubility characteristics that are important for its applications and behavior in various environments.

General Solubility Behavior

The solubility of methyl 2-nitroacetate can be described as:

  • Polar Solvents: This compound is generally soluble in polar solvents due to the presence of the nitro group, which increases its polarity.
  • Non-Polar Solvents: It is less soluble in non-polar solvents, reflecting the limited interaction between non-polar molecules and the polar functionalities of the compound.
  • Water Solubility: Methyl 2-nitroacetate has limited solubility in water, which can be attributed to the hydrophobic carbon chain that competes with the hydrophilic nitro and ester functional groups.

Factors Influencing Solubility

Several factors can influence the solubility of methyl 2-nitroacetate:

  • Temperature: Increased temperature typically enhances solubility for most organic compounds, including methyl 2-nitroacetate.
  • pH of Solvent: The acidic or basic characteristics of the solvent can alter the ionization of the compound, affecting solubility.
  • Presence of Other Solutes: Solubility can change in the presence of salts or other solutes, which may cause salting-out or salting-in effects.

In conclusion, understanding the solubility of methyl 2-nitroacetate is essential for predicting its behavior in chemical reactions and its interactions with other substances. The interplay of its molecular structure and environmental conditions largely determines its solubility profile.

Interesting facts

Exploring Methyl 2-Nitroacetate

Methyl 2-nitroacetate is a fascinating compound that holds significance in various fields of chemistry, especially in organic synthesis. Here are some intriguing facts about this compound:

  • Synthesis: This compound can be synthesized through a reaction between methyl acetate and nitric acid, showcasing the versatility of esterification reactions in organic chemistry.
  • Reactivity: Methyl 2-nitroacetate acts as a useful synthetic intermediate, particularly in the production of amino acids and other biologically relevant molecules.
  • Biological Aspects: Research has indicated that the nitro group can impart interesting biological properties, making it a subject of study for potential pharmaceutical applications.
  • Applications: Beyond its synthetic versatility, this compound is used in the manufacture of dyes and pesticides, illustrating its role in agrochemical and industrial processes.
  • Environmental Concerns: Being an ester, it may have implications for the environment, leading to discussions around its biodegradability and impact when released into ecosystems.
  • Historical Significance: Compounds like methyl 2-nitroacetate have paved the way for advancements in both organic chemistry and materials science, demonstrating the interconnected nature of chemical research.

As you delve deeper into the world of methyl 2-nitroacetate, consider how its unique properties and reactions continue to shape advancements in science. In the words of a famous chemist, "The beauty of chemistry lies in its endless possibilities." Let this compound inspire your own exploration of chemical creativity!

Synonyms
Methyl nitroacetate
Methyl 2-nitroacetate
Nitroacetic acid methyl ester
EINECS 219-622-0
NSC 16153
BRN 1758670
Methyl a-nitroacetate
DTXSID10179539
DTXCID20102030
219-622-0
4-02-00-00537 (beilstein handbook reference)
albswlmuhhzllr-uhfffaoysa-n
2483-57-0
ACETIC ACID, NITRO-, METHYL ESTER
Acetic acid, 2-nitro-, methyl ester
MFCD00075480
methyl nitro acetate
Methyl2-nitroacetate
methyl 2-nitroethanoate
Methyl nitroacetate, 98%
nitroacetic acid methylester
SCHEMBL8143
2-nitroacetic acid methyl ester
NSC16153
STR09118
BBL104276
NSC-16153
STL558476
AKOS009157148
SY001008
CS-0130670
N0656
NS00027746
EN300-60150
A817518