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Methyl 2-oxo-2H-chromene-3-carboxylate

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Identification
Molecular formula
C11H8O4
CAS number
6064-46-6
IUPAC name
methyl 2-oxochromene-3-carboxylate
State
State

At room temperature, Methyl 2-oxo-2H-chromene-3-carboxylate is typically found in the solid state. It can be handled as a powder or crystalline solid for various applications. The compound is not volatile and remains stable at ambient conditions.

Melting point (Celsius)
78.00
Melting point (Kelvin)
351.15
Boiling point (Celsius)
460.80
Boiling point (Kelvin)
733.95
General information
Molecular weight
218.18g/mol
Molar mass
218.1830g/mol
Density
1.3040g/cm3
Appearence

Methyl 2-oxo-2H-chromene-3-carboxylate appears as a crystalline solid. The color can vary depending on purity and specific conditions, but it typically displays a range of colors from light yellow to off-white. The compound may also appear as a powder depending on how it has been processed for use.

Comment on solubility

Solubility of Methyl 2-Oxochromene-3-Carboxylate

Methyl 2-oxochromene-3-carboxylate, a compound characterized by its unique structure, exhibits a noteworthy solubility profile. Generally speaking, several factors influence the solubility of such organic compounds:

  • Polarity: Due to the presence of both polar and nonpolar groups in methyl 2-oxochromene-3-carboxylate, it tends to have moderate solubility in polar solvents such as water and alcohols.
  • Hydrogen Bonding: The compound has potential sites for hydrogen bonding, which can enhance its solubility in polar solvents, enabling interactions with solvent molecules.
  • Solvent Compatibility: Its solubility is often higher in organic solvents like ethyl acetate, methanol, and dimethyl sulfoxide (DMSO), making these common choices for dissolution in laboratory settings.

When discussing solubility, it is important to mention that:

  • The presence of methyl and carboxylate functional groups tends to affect the compound's overall solubility behavior.
  • Temperature can also play a vital role; typically, increased temperatures improve solubility in many organic solvents.

Therefore, in laboratory practices and applications, understanding the solubility of methyl 2-oxochromene-3-carboxylate is critical for its effective use in various chemical reactions and formulations. To summarize, its moderate solubility in polar solvents and good solubility in more organic solvents highlights its versatility in practical applications.

Interesting facts

Interesting Facts about Methyl 2-Oxochromene-3-Carboxylate

Methyl 2-oxochromene-3-carboxylate is an intriguing compound that falls within the class of chromenone derivatives, which are notable for their various biological activities and potential applications.

Notable Characteristics:

  • Structure and Function: The chromene core structure contributes to the compound's **reactivity** and **stability**, making it a viable candidate for synthetic chemistry.
  • Diverse Applications: This compound is utilized in fields like medicinal chemistry and agricultural science. It has been studied for its potential anti-inflammatory and antitumor properties, which makes it a focus for researchers seeking new therapeutic agents.
  • Natural Sources: Compounds similar to methyl 2-oxochromene-3-carboxylate can be found in various plants, contributing to their medicinal properties. This underscores the value of natural products in drug discovery.

Research and Impact:

Studies have indicated that compounds of this nature may act as key intermediates in the synthesis of bioactive molecules, leading to their relevance in designing new pharmaceuticals. As noted in one study, "the exploration of chromenone derivatives has opened new avenues in drug development, showcasing the compound’s versatility.”

In conclusion, methyl 2-oxochromene-3-carboxylate is not just a chemical formula but a gateway to innovative research and applications that could impact various fields significantly. The ongoing exploration in this domain might lead to groundbreaking discoveries that bridge the gap between traditional knowledge and modern scientific advancements.

Synonyms
21259-42-7
Methyl coumarin-3-carboxylate
Methyl 2-oxo-2H-chromene-3-carboxylate
methyl 2-oxochromene-3-carboxylate
2-Oxo-2H-1-benzopyran-3-carboxylic acid methyl ester
2H-1-BENZOPYRAN-3-CARBOXYLIC ACID, 2-OXO-, METHYL ESTER
AI 3-36065
DTXSID30175513
BRN 0176130
AI3-36065
RefChem:1089348
2-Oxo-2H-chromene-3-carboxylic acid methyl ester
SCHEMBL76086
MLS000523665
IFLab1_000621
CHEMBL1569462
DTXCID5098004
JZAJARGAUOHFCU-UHFFFAOYSA-N
HMS1413M05
HMS2378G16
CCG-15545
MFCD00249953
STK749977
AKOS000348717
IDI1_008840
UPCMLD0ENAT5575665:001
NCGC00245182-01
SMR000122738
ST073227
SY302071
Methyl 2-oxo-2H-chromene-3-carboxylate #
EU-0001673
Methyl 2-oxo-2H-1-benzopyran-3-carboxylate
AE-848/32005040
SR-01000401137
SR-01000401137-1
Z18746129
F0110-0035