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Methyl 2-pyrrolidone

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Identification
Molecular formula
C7H13NO2
CAS number
16068-18-3
IUPAC name
methyl 2-pyrrolidin-1-ylacetate
State
State

At room temperature, methyl 2-pyrrolidineacetate is a liquid.

Melting point (Celsius)
-64.00
Melting point (Kelvin)
209.15
Boiling point (Celsius)
202.00
Boiling point (Kelvin)
475.15
General information
Molecular weight
129.17g/mol
Molar mass
129.1730g/mol
Density
1.0466g/cm3
Appearence

Methyl 2-pyrrolidineacetate appears as a colorless to pale yellow liquid. It may have a faint, amine-like odor.

Comment on solubility

Solubility of Methyl 2-pyrrolidin-1-ylacetate

Methyl 2-pyrrolidin-1-ylacetate, with its unique structure, exhibits interesting solubility characteristics that are worth exploring. Here are some key points to consider regarding its solubility:

  • Polar Characteristics: The presence of both the ester group and the nitrogen in the pyrrolidine ring contributes to the compound's polar nature, enhancing its ability to dissolve in polar solvents.
  • Solvent Compatibility: This compound is generally soluble in water and polar organic solvents such as ethanol and methanol, owing to its polarity.
  • Limited Nonpolar Solubility: In contrast, methyl 2-pyrrolidin-1-ylacetate has low solubility in nonpolar solvents, indicating that its structure does not favor interaction with hydrophobic environments.
  • Applications in Organic Chemistry: The solubility profile makes it suitable for various chemical reactions and applications, particularly in aqueous environments or when paired with polar solvents.

Overall, the solubility of methyl 2-pyrrolidin-1-ylacetate underscores its versatility in different chemical conditions, making it a valuable compound in synthetic chemistry and pharmaceuticals.

Interesting facts

Interesting Facts About Methyl 2-Pyrrolidin-1-ylacetate

Methyl 2-pyrrolidin-1-ylacetate is a fascinating compound that belongs to the family of pyrrolidine derivatives. This compound has garnered interest in both academia and industry due to its unique properties and applications. Here are some notable facts:

  • Structural Intrigue: The structure of methyl 2-pyrrolidin-1-ylacetate features a pyrrolidine ring, a five-membered cyclic structure which contributes significantly to its chemical behavior.
  • Synthesis Potential: This compound can be synthesized through various methods, often involving the use of readily available starting materials, which makes it an attractive target for chemical synthesis.
  • Applications in Pharmaceuticals: Methyl 2-pyrrolidin-1-ylacetate has potential applications in drug development. Its derivatives could be explored for pharmacological activities, including analgesic and anti-inflammatory properties.
  • Role as a Building Block: Its structure allows it to serve as a versatile building block in organic synthesis, leading to complex molecules that can be used in various fields, including materials science and medicinal chemistry.
  • Research Opportunities: The compound is a subject of ongoing research, focusing on its reaction mechanisms and interactions with biological systems. This opens up avenues for discovering new functions and applications.

In summary, methyl 2-pyrrolidin-1-ylacetate exemplifies the dynamic nature of organic compounds, showcasing how slight structural variations can have significant implications for their utility in science and technology. As researchers continue to explore this compound, its full potential is yet to be entirely realized.

Synonyms
22041-18-5
Methyl 1-pyrrolidineacetate
methyl 2-(pyrrolidin-1-yl)acetate
Methyl (1-pyrrolidinyl)acetate
ACETIC ACID, PYRROLIDIN-1-YL-, METHYL ESTER
BRN 4176573
DTXSID20176514
RefChem:552299
1-Pyrrolidineacetic acid, methyl ester (8CI,9CI)
DTXCID2099005
863-023-2
METHYL1-PYRROLIDINEACETATE
methyl 2-pyrrolidin-1-ylacetate
MFCD01672788
1-Pyrrolidineacetic acid, methyl ester
methyl pyrrolidinyl acetate
SCHEMBL65441
SCHEMBL22684497
BMWOSLXYXGTLAR-UHFFFAOYSA-N
Methyl 2-(1-Pyrrolidinyl)acetate
AKOS003973583
pyrrolidin-1-yl-acetic acid methyl ester
SY179248
DS-022002
EN300-43448
F94610
672M788
Z57725199