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Methyl trichloroacetate

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Identification
Molecular formula
C3H3Cl3O2
CAS number
598-99-2
IUPAC name
methyl 2,2,2-trichloroacetate
State
State

At room temperature, methyl trichloroacetate is a liquid. It is not prone to crystallization or solidification under normal conditions and remains a mobile liquid when stored properly.

Melting point (Celsius)
-29.00
Melting point (Kelvin)
244.15
Boiling point (Celsius)
127.00
Boiling point (Kelvin)
400.15
General information
Molecular weight
163.43g/mol
Molar mass
163.4290g/mol
Density
1.4750g/cm3
Appearence

Methyl trichloroacetate is a colorless to pale yellow liquid. It is known for its distinct pungent odor typical of esters of chlorinated acetic acids. The compound is often used in laboratory settings and is usually a clear liquid when pure.

Comment on solubility

Solubility of Methyl 2,2,2-Trichloroacetate

Methyl 2,2,2-trichloroacetate, with the chemical formula C4HCl3O2, presents interesting solubility characteristics that are noteworthy for various applications. This compound exhibits a moderate solubility in organic solvents while showing limited solubility in water. Here are some important points regarding its solubility:

  • Polar Character: The presence of the carboxylate group contributes to some degree of polarity, aiding in solubility in polar organic solvents.
  • Water Interaction: Due to its heavy chlorination and bulky structure, methyl 2,2,2-trichloroacetate is less effective in forming hydrogen bonds with water molecules, which significantly decreases its solubility in water.
  • Solvent Compatibility: It dissolves well in a range of organic solvents such as ethanol, acetone, and chloroform, enabling it to be utilized in chemical synthesis and extraction processes.

As stated succinctly, "Solubility is the gateway to reactivity." Therefore, understanding the solubility of methyl 2,2,2-trichloroacetate is crucial for chemists when predicting its behavior in various environments and applications. Overall, its solubility profile underscores the necessity of selecting appropriate solvents for effective utilization in laboratory settings.

Interesting facts

Interesting Facts About Methyl 2,2,2-Trichloroacetate

Methyl 2,2,2-trichloroacetate is a fascinating compound with various applications in the field of chemistry and industry. Here are some notable points:

  • Chemical Significance: This compound is an ester derived from trichloroacetic acid and methanol. Esters are significant in organic chemistry due to their prevalence in nature and their roles in synthetic pathways.
  • Reactivity: Methyl 2,2,2-trichloroacetate is known for its reactivity, particularly in substitution reactions. It undergoes nucleophilic substitution due to the presence of the trichloroacetate group, which acts as a leaving group, making it versatile for various synthetic applications.
  • Applications: This compound has utility in the synthesis of several pharmaceuticals, agrochemicals, and other organic compounds. It serves as an important building block in the creation of more complex molecules.
  • Safety and Handling: Methyl 2,2,2-trichloroacetate must be handled with care. It is essential to follow safety protocols as it can pose risks associated with toxic and environmental effects.
  • Historical Context: Compounds containing trichloro groups have historical significance in the development of chemical reactions and methodologies in organic synthesis, showcasing their importance in advancing the field of chemistry.

To quote a famous chemist: "Chemistry is not just about understanding substances; it is about understanding their transformations and the stories they tell through their interactions."

This illustrates not only the scientific aspect of methyl 2,2,2-trichloroacetate but also its broad implications for research and industry. This compound represents just one of many fascinating contributions to the diverse world of chemical compounds.

Synonyms
METHYL TRICHLOROACETATE
598-99-2
Acetic acid, trichloro-, methyl ester
Methyl trichloroacetic acid
Acetic acid, 2,2,2-trichloro-, methyl ester
EINECS 209-960-7
NSC 38452
UN2533
DTXSID0060517
EC 209-960-7
DTXCID3042714
Acetic acid, trichloro, methyl ester
Acetic acid, 2,2,2trichloro, methyl ester
209-960-7
inchi=1/c3h3cl3o2/c1-8-2(7)3(4,5)6/h1h
methyl 2,2,2-trichloroacetate
Trichloroacetic Acid Methyl Ester
Methyl trichlroracetate
NSC-38452
Methyltrichloroacetate
Acetic acid, trichloro-, methyl ester (6CI,7CI,8CI,9CI); Methyl trichloroacetate; Methyl a,a,a-trichloroacetate; NSC 38452; Trichloroacetic acid methyl ester
MFCD00000794
N9HBT62EHK
Methyl trichloroacetate, 99%
SCHEMBL722674
Trichloroacetic acid-methyl ester
NSC38452
AKOS015907942
methyl 2,2,2-tris(chloranyl)ethanoate
UN 2533
2,2,2-trichloroacetic acid methyl ester
FM162268
LS-12949
NS00022472
T1013
Methyl trichloroacetate [UN2533] [Poison]
E78925
A832533
Q63395408
F1905-7029
Methyl trichloroacetate, PESTANAL(R), analytical standard
Trichloroacetic acid-methyl ester 1000 microg/mL in Methyl-tert-butyl ether