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Amitriptyline hydrochloride

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Identification
Molecular formula
C20H24ClN
CAS number
549-18-8
IUPAC name
methyl-[3-(2-methyl-6H-benzo[c][1]benzothiepin-11-ylidene)propyl]ammonium;chloride
State
State

Amitriptyline hydrochloride is commonly found in a solid state at room temperature.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
291.00
Boiling point (Kelvin)
564.15
General information
Molecular weight
313.87g/mol
Molar mass
313.8670g/mol
Density
1.0080g/cm3
Appearence

Amitriptyline hydrochloride appears as white, crystalline powder which is odorless or has a very faint odor. It is known to be hygroscopic (it can absorb moisture from the air).

Comment on solubility

Solubility of Methyl-[3-(2-methyl-6H-benzo[c][1]benzothiepin-11-ylidene)propyl]ammonium;chloride

The solubility of methyl-[3-(2-methyl-6H-benzo[c][1]benzothiepin-11-ylidene)propyl]ammonium;chloride can be quite intriguing given its complex structure. Understanding its solubility involves several factors:

  • Polarity of the Compound: This compound features both hydrophobic (non-polar) and hydrophilic (polar) characteristics due to its ammonium group and aromatic structures.
  • Influence of Chloride Ion: The chloride (Cl-) component typically enhances solubility in polar solvents such as water, allowing for ion-dipole interactions.
  • Solvent Compatibility: While this compound may exhibit some solubility in water due to the ammonium cation, it is likely to be more soluble in organic solvents like methanol or ethanol due to its bulky structure.
  • Effect of Temperature: As is common with many compounds, an increase in temperature can lead to higher solubility in many solvents as it facilitates molecular interactions and disrupts solvation shells.

In summary, the solubility of methyl-[3-(2-methyl-6H-benzo[c][1]benzothiepin-11-ylidene)propyl]ammonium;chloride is a balance between its hydrophilic and hydrophobic properties, solvent choice, and temperature. Researchers often find that experimenting with various solvents offers insight into the optimal conditions for dissolving this unique compound.

Interesting facts

Interesting Facts about Methyl-[3-(2-methyl-6H-benzo[c][1]benzothiepin-11-ylidene)propyl]ammonium Chloride

This fascinating compound, methyl-[3-(2-methyl-6H-benzo[c][1]benzothiepin-11-ylidene)propyl]ammonium chloride, belongs to a class of chemicals that can influence various biochemical pathways. Below are some engaging aspects of this compound from a scientific perspective:

  • Structural Complexity: The compound features a unique structure that includes both a benzothiepin moiety and a quaternary ammonium group. This architectural complexity often translates to unique properties and potential biological activities.
  • Biological Significance: Benzothiepin derivatives are known for their pharmacological activities. Research has suggested these compounds may exhibit antidepressant or anti-inflammatory properties, making them of interest in the field of medicinal chemistry.
  • Ion Exchange Properties: As an ammonium salt, this compound may exhibit interesting ion exchange behaviors. Investigating these can reveal insights into its interactions with biological membranes or other ionic solutions.
  • Potential Applications: Given its structure, this compound has potential applications in drug development, especially in targeting central nervous system disorders. Novel compounds can yield new therapeutic candidates that improve upon existing treatments.
  • Research and Development: As a relatively complex organic molecule, its synthesis may involve multiple reaction steps, providing plentiful opportunities for experimentation with reaction conditions and methodologies.

In summary, methyl-[3-(2-methyl-6H-benzo[c][1]benzothiepin-11-ylidene)propyl]ammonium chloride stands as a testament to the intricacies of organic chemistry, where structure often dictates function. The continued study of this compound may unlock new understanding in both synthetic pathways and therapeutic potentials.