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Methyl 3-[3-(2-fluoroethylamino)phenyl]propanoate hydrochloride

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Identification
Molecular formula
C12H16ClFNO2
CAS number
136465-57-9
IUPAC name
methyl 3-[3-(2-fluoroethylamino)phenyl]propanoate;hydrochloride
State
State

At room temperature, methyl 3-[3-(2-fluoroethylamino)phenyl]propanoate hydrochloride is typically found in a solid state.

Melting point (Celsius)
80.00
Melting point (Kelvin)
353.15
Boiling point (Celsius)
342.00
Boiling point (Kelvin)
615.15
General information
Molecular weight
245.71g/mol
Molar mass
245.7090g/mol
Density
1.1650g/cm3
Appearence

Methyl 3-[3-(2-fluoroethylamino)phenyl]propanoate hydrochloride is typically found as a white to off-white crystalline powder. It may also appear as a fine solid with no distinct odor.

Comment on solubility

Solubility of Methyl 3-[3-(2-fluoroethylamino)phenyl]propanoate; Hydrochloride

The solubility of methyl 3-[3-(2-fluoroethylamino)phenyl]propanoate; hydrochloride can be quite interesting due to its specific chemical structure. As a hydrochloride salt, this compound is generally expected to exhibit improved solubility in polar solvents, particularly water. Here are several important factors influencing its solubility:

  • Polarity: The presence of the hydrochloride moiety enhances its ability to dissolve in water compared to its free base form. This is due to the ionic nature of the hydrochloride, which interacts well with water molecules.
  • Temperature: Increased temperatures typically lead to greater solubility for many salts, including hydrochlorides. This is valuable during dissolution processes.
  • pH Levels: As a basic amine in its structure, changes in the pH of the solvent may also impact solubility, potentially leading to variations based on the chemical environment.
  • Concentration: Like many compounds, solubility may decrease as the concentration of solute increases, approaching saturation point.

In summary, methyl 3-[3-(2-fluoroethylamino)phenyl]propanoate; hydrochloride is likely soluble in water and offers various pathways for solubility enhancement depending on its surroundings. It is a prime example of how molecular structure influences solubility, making it a compelling compound for further study.

Interesting facts

Exploring Methyl 3-[3-(2-Fluoroethylamino)phenyl]propanoate Hydrochloride

Methyl 3-[3-(2-fluoroethylamino)phenyl]propanoate hydrochloride is an intriguing compound in the field of medicinal chemistry. Its unique structure lends itself to several interesting features:

  • Pharmaceutical Potential: This compound possesses a fluorinated moiety, which often enhances biological activity and metabolic stability. Fluorine substitution can improve binding affinity to target receptors, making it a candidate for drug development.

  • Amino Group Influence: The presence of an amino group allows for interactions with various biological targets, potentially leading to applications in treating neurological disorders. It is known that amines can participate in hydrogen bonding, which may contribute to increased biological efficacy.

  • Versatile Synthesis: The synthesis of this compound involves the use of various synthetic strategies that can be adapted or modified, fostering innovation in the field. Chemists often explore novel reaction pathways to enhance yield and purity.

  • Hydrochloride Form: The hydrochloride salt form of this compound plays a crucial role in its solubility and stability during storage and handling. Salts can significantly influence pharmacokinetics, affecting how the drug is absorbed and metabolized in the body.

As with many compounds featuring unique structural elements, research continues to unveil the full potential of methyl 3-[3-(2-fluoroethylamino)phenyl]propanoate hydrochloride. Scientific inquiry into its properties and applications holds promise for advancements in pharmaceuticals.

Synonyms
1212-39-1
HYDROCINNAMIC ACID, 3-(2-FLUOROETHYLAMINO)-, METHYL ESTER, HYDROCHLORIDE
NSC 79493
Methyl 3-(2-fluoroethylamino)hydrocinnamate hydrochloride
Methyl N-2-fluoroethyl-3-(m-aminophenyl)propionate hydrochloride
DTXSID70153178
m-((2-Fluoroethyl)amino)hydrocinnamic acid methyl ester hydrochloride
DTXCID4075669
NSC-79493
methyl 3-[3-(2-fluoroethylamino)phenyl]propanoate;hydrochloride
Methyl 3-(3-((2-fluoroethyl)amino)phenyl)propanoate hydrochloride
Methyl 3-{3-[(2-fluoroethyl)amino]phenyl}propanoate hydrochloride
starbld0044593
5ZT7KKX82F
NSC79493
AKOS040752046
Hydrocinnamic acid, m-[(2-fluoroethyl)amino]-, methyl ester, hydrochloride
Benzenepropanoic acid, 3-[(2-fluoroethyl)amino]-, methyl ester, hydrochloride
Benzenepropanoic acid, 3-[(2-fluoroethyl)amino]-, methyl ester, hydrochloride (1:1)