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Methyl 3-(aziridin-1-yl)propanoate

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Identification
Molecular formula
C7H13NO2
CAS number
.62368-06-1
IUPAC name
methyl 3-(aziridin-1-yl)propanoate
State
State

Methyl 3-(aziridin-1-yl)propanoate is a liquid at room temperature.

Melting point (Celsius)
-50.00
Melting point (Kelvin)
223.15
Boiling point (Celsius)
168.00
Boiling point (Kelvin)
441.15
General information
Molecular weight
129.18g/mol
Molar mass
129.1570g/mol
Density
1.0000g/cm3
Appearence

Methyl 3-(aziridin-1-yl)propanoate is typically found as a colorless to pale yellow liquid, depending on its purity and specific storage conditions. It is often used as an intermediate in organic synthesis and could have a slight amine-like odor due to its aziridine content.

Comment on solubility

Solubility of Methyl 3-(aziridin-1-yl)propanoate

Methyl 3-(aziridin-1-yl)propanoate is a unique compound that exhibits interesting solubility characteristics. The solubility of this compound can be affected by various factors such as the polarity of the solvent and the molecular structure of the compound. Here are some key points to consider:

  • Polarity: Methyl 3-(aziridin-1-yl)propanoate features both hydrophobic (non-polar) and hydrophilic (polar) regions, which influences its solubility in different solvents.
  • Solvent Compatibility: This compound is generally more soluble in organic solvents, such as ethanol or acetone, which can effectively interact with its structure.
  • Water Solubility: Due to its aziridine moiety, the water solubility could be limited, as it may not readily associate with water molecules.
  • Concentration Factors: At higher concentrations, the solubility behavior may change, impacting its applications in various fields.

It is important to recognize that the solubility of methyl 3-(aziridin-1-yl)propanoate is a complex phenomenon, influenced by the solvent environment and the specific interactions at play. As a general rule, understanding the structure-property relationship is essential when predicting solubility outcomes.

Interesting facts

Exploring Methyl 3-(aziridin-1-yl)propanoate

Methyl 3-(aziridin-1-yl)propanoate is a unique compound that bridges the realms of synthetic chemistry and biological applications. Here are some fascinating aspects of this compound:

  • Structural Significance: The presence of the aziridine ring—a three-membered cyclic amine—enhances the compound's reactivity, making it valuable in organic synthesis.
  • Synthetic Use: This compound is often made through the reaction of propanoic acid derivatives with aziridine, showcasing the versatility of both elements in creating diverse molecular architectures.
  • Biological Activity: Methyl 3-(aziridin-1-yl)propanoate has been studied for its potential in medicinal chemistry, particularly as a possible antimicrobial agent. Its unique structure may contribute to efficacy against various pathogens.
  • Reaction Mechanisms: The aziridine moiety in this compound can undergo intriguing reactions, such as ring-opening; this phenomenon is often employed to develop complex molecules in drug design.
  • Regioselectivity: The ability to selectively functionalize specific positions on the aziridine ring is a major focus in research, as it paves the way for the discovery of new therapeutics.

In conclusion, methyl 3-(aziridin-1-yl)propanoate is more than just a name; it represents a playground for chemists exploring innovative solutions to synthetic challenges and therapeutic potentials. As one researcher aptly put it, “The magic of chemistry lies in the simplicity of its building blocks and the complexity of the structures they can create.”

Synonyms
Methyl 3-(1-aziridinyl)propionate
1073-77-4
3-Ethyleniminopropionate
Methyl aziridine-1-propionate
methyl 3-(aziridin-1-yl)propanoate
Methyl 1-aziridinepropionate
1-Aziridinepropanoic acid, methyl ester
Methyl 3-ethyleniminopropionate
1-(2-Methoxycarbonylethyl)aziridine
1-(2-Methoxycarbonylethyl)ethylenimine
1-AZIRIDINEPROPIONIC ACID, METHYL ESTER
TFY7037IGL
NSC-101297
Methyl .beta.-(1-aziridinyl)propionate
EINECS 214-034-0
Methyl beta-(1-aziridinyl)propionate
UNII-TFY7037IGL
NSC 101297
BRN 0113048
NCIOpen2_001869
N-(carbomethoxy-ethyl)aziridine
SCHEMBL1174392
DTXSID90148001
ETHYLENIMINOPROPIONATE, 3-
NSC101297
N-(2-CARBOMETHOXYETHYL)AZIRIDINE
NS00023457
Q27289946