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Coumarin-6-carboxylic acid methyl ester

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Identification
Molecular formula
C14H8O6
CAS number
144981-77-9
IUPAC name
methyl 3-oxaldehydoyl-2-oxo-chromene-6-carboxylate
State
State

At room temperature, this compound is in a solid state, typically found as a powder or crystalline solid.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
410.00
Boiling point (Kelvin)
683.15
General information
Molecular weight
276.24g/mol
Molar mass
276.2390g/mol
Density
1.4000g/cm3
Appearence

Methyl 3-oxaldehydoyl-2-oxo-chromene-6-carboxylate is typically a pale yellow to yellow crystalline powder. It may also appear slightly greenish depending on purity and specific conditions.

Comment on solubility

Solubility of Methyl 3-oxaldehydoyl-2-oxo-chromene-6-carboxylate

Methyl 3-oxaldehydoyl-2-oxo-chromene-6-carboxylate is an intriguing compound when it comes to solubility characteristics. Generally speaking, the solubility of organic compounds can be influenced by various factors including:

  • Polarity: The presence of polar functional groups in the compound can enhance its solubility in polar solvents like water.
  • Hydrophobic regions: Conversely, larger hydrophobic regions tend to reduce solubility in polar solvents.
  • Hydrogen bonding: Capable of forming hydrogen bonds, the compound may demonstrate increased solubility in solvents that can engage in such interactions.

In the case of methyl 3-oxaldehydoyl-2-oxo-chromene-6-carboxylate, we can anticipate:

  • A moderate solubility in organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO), due to functional groups that favor interaction with these media.
  • Relatively low solubility in non-polar solvents like hexane or benzene, attributed to the presence of polar carboxylate structures.

Hence, understanding the solubility pattern of this compound is crucial for its potential applications in various fields such as pharmaceuticals and materials science. As is often quoted in chemistry, "Like dissolves like," indicating that the chemical nature of solvents plays a significant role in the solubility of compounds.

Interesting facts

Interesting Facts about Methyl 3-Oxaldehydoyl-2-Oxo-Chromene-6-Carboxylate

Methyl 3-oxaldehydoyl-2-oxo-chromene-6-carboxylate is a striking compound belonging to the chromene class, which is known for its diverse applications and fascinating chemical properties. Here are some intriguing aspects of this compound:

  • Chromene Structure: The compound features a chromene core—a bicyclic structure that comprises a benzene and a pyran ring. This unique structure is significant in pharmaceuticals due to its biological activity.
  • Versatile Functionality: The presence of both aldehyde and carboxylate functional groups in this compound enables it to engage in various chemical reactions, making it a versatile building block for synthesizing more complex molecules.
  • Biological Relevance: Compounds related to chromenes are notable for their medicinal properties. They often exhibit anti-inflammatory, antimicrobial, and antioxidant activities, which make them valuable in drug development.
  • Natural Occurrence: Chromenes are not only synthetically important but are also found in many natural products, including flavonoids, which contribute to the color and flavor of many plants and fruits.
  • Research Potential: The potential for this compound in research is vast, particularly in fields such as organic synthesis, medicinal chemistry, and materials science. Its derivatives could lead to novel compounds with enhanced properties.

The ongoing exploration of methyl 3-oxaldehydoyl-2-oxo-chromene-6-carboxylate highlights the intricate interplay between structure and function in chemistry. As scientists continue to uncover its properties, we can anticipate exciting developments in areas ranging from drug discovery to materials innovation.

Synonyms
6468-78-6
BRN 1385962
3-Glyoxyloyl-6-carbomethoxycoumarin
SC-347
2H-1-BENZOPYRAN-6-CARBOXYLIC ACID, 3-GLYOXYLOYL-2-OXO-, METHYL ESTER
DTXSID10214979
3-Glyoxyloyl-2-oxo-2H-1-benzopyran-6-carboxylic acid methyl ester
DTXCID90137470
5-18-08-00686 (beilstein handbook reference)
Methyl 2-oxo-3-(oxoacetyl)-2H-chromene-6-carboxylate