Skip to main content

Methyl acetoacetate

ADVERTISEMENT
Identification
Molecular formula
C5H8O3
CAS number
105-45-3
IUPAC name
methyl 3-oxobutanoate
State
State

At room temperature, methyl acetoacetate is a liquid.

Melting point (Celsius)
-23.00
Melting point (Kelvin)
250.15
Boiling point (Celsius)
170.50
Boiling point (Kelvin)
443.65
General information
Molecular weight
116.12g/mol
Molar mass
116.1150g/mol
Density
1.0280g/cm3
Appearence

Methyl acetoacetate is a colorless liquid with a fruity odor. It is a clear liquid that exhibits good solubility in most organic solvents and is also partially soluble in water.

Comment on solubility

Solubility of Methyl 3-oxobutanoate

Methyl 3-oxobutanoate, also known for its characteristic structure, exhibits interesting solubility properties that can be influenced by various factors. Generally, the solubility of this compound can be summarized as follows:

  • Polar solvents: Methyl 3-oxobutanoate tends to be soluble in polar solvents such as water and alcohols. This is due to the presence of polar functional groups that can interact favorably with solvent molecules.
  • Non-polar solvents: Conversely, its solubility in non-polar solvents is limited, reflecting the compound's moderate polarity. This characteristic is typical for many esters.
  • Temperature effect: Like many organic compounds, the solubility of methyl 3-oxobutanoate increases with temperature. This phenomenon is vital in applications where temperature control can enhance solubility for reactions or extractions.

In essence, the solubility of methyl 3-oxobutanoate is an important consideration in its use and application within various chemical processes. As the compound dissolves better in polar environments, it is essential for researchers and practitioners to consider the appropriate solvent systems to maximize efficiency and reactivity.

Interesting facts

Interesting Facts about Methyl 3-Oxobutanoate

Methyl 3-oxobutanoate, an intriguing ester compound, holds significance in both organic synthesis and biochemistry. This compound is characterized by its role as a versatile building block in the creation of various chemical structures. Here are some notable aspects of methyl 3-oxobutanoate:

  • Versatile Intermediate: It serves as a pivotal intermediate in the synthesis of pharmaceuticals and agrochemicals, showcasing its importance in the chemical industry.
  • Flavor and Fragrance: Methyl 3-oxobutanoate contributes to the flavor and fragrance industry, often utilized in creating fruity and sweet scents, enhancing the sensory experience of various products.
  • Biological Significance: This compound can also play a role in metabolic pathways, potentially influencing the synthesis of important biomolecules in living organisms.
  • Synthesis from Acetoacetic Acid: One of the common methods to synthesize methyl 3-oxobutanoate is through the esterification of acetoacetic acid, which highlights its relationship with other key organic compounds.

As a chemistry student or researcher, understanding the properties and applications of compounds like methyl 3-oxobutanoate not only enriches your knowledge but also empowers you to innovate in the fields of organic chemistry and materials science. Embrace the fascinating world of esters and their myriad uses!

Synonyms
METHYL ACETOACETATE
Methyl 3-oxobutanoate
105-45-3
Methylacetoacetate
Acetoacetic acid methyl ester
Methyl acetylacetate
Methyl 3-oxobutyrate
Butanoic acid, 3-oxo-, methyl ester
Methyl acetylacetonate
3-Oxobutanoic acid methyl ester
Acetoacetic methyl ester
Acetoacetic acid, methyl ester
1-Methoxybutane-1,3-dione
Methylacetoacetic acid
Methylester kyseliny acetoctove
CCRIS 2302
HSDB 1083
EINECS 203-299-8
CW4I82QAX1
Methylester kyseliny acetoctove [Czech]
DTXSID9026716
AI3-06000
3-oxo-Butanoic acid methyl ester
MFCD00008784
Acetoacetic acid-methyl ester
DTXCID706716
3-Oxobutyric Acid Methyl Ester
3-oxo-butyric acid methyl ester
CHEMBL3186053
METHYL ACETOACETATE [MI]
EC 203-299-8
METHYL ACETOACETATE [HSDB]
UNII-CW4I82QAX1
methyl acetoactate
methylaceto acetate
Methyl 3oxobutyrate
methyl aceto acetate
Methyl 3oxobutanoate
MeCOCH2COOMe
methyl-3-oxobutanoate
methyl 3-oxo-butyrate
1Methoxybutane1,3dione
Acetoacetate methyl ester
Methyl 3-oxobutanoic acid
SCHEMBL1162
Methyl acetoacetate, >=99%
METHYL-3-OXO-BUTYRATE
3Oxobutanoic acid methyl ester
aceto-acetic acid methyl ester
methyl 3-oxidanylidenebutanoate
Methyl acetylacetate (Standard)
HY-Y1298R
3-oxobutanoic acid, methyl ester
CHEBI:166454
Butanoic acid, 3oxo, methyl ester
HY-Y1298
Tox21_200162
BBL011420
BDBM50502126
s3091
STL146527
AKOS000118978
Methyl acetoacetate, analytical standard
NCGC00248545-01
NCGC00257716-01
CAS-105-45-3
BUTANOIC ACID, 3-OXO-METHYL ESTER
Methyl acetoacetate, ReagentPlus(R), 99%
A0650
CS-0017265
NS00004928
EN300-19130
D70329
A801244
BUTANOIC ACID, 3-OXO-METHYL ESTER (9CI)
Methyl acetoacetate, Lonza quality, >=99% (GC)
Methyl acetoacetate, Vetec(TM) reagent grade, 98%
Q63395658
F0001-0105
Z104472888
Methyl acetoacetate, produced by Wacker Chemie AG, Burghausen, Germany, >=99.0% (GC)
203-299-8