Skip to main content

Methyl gallate

ADVERTISEMENT
Identification
Molecular formula
C8H8O5
CAS number
99-24-1
IUPAC name
methyl 3,4,5-trihydroxybenzoate
State
State
Methyl gallate is solid at room temperature and typically appears as a granular crystalline powder.
Melting point (Celsius)
201.00
Melting point (Kelvin)
474.15
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
184.15g/mol
Molar mass
184.1540g/mol
Density
1.6450g/cm3
Appearence

Methyl gallate appears as a white or off-white crystalline powder. It is often used in research and industrial applications due to its antioxidant properties and can be found in various plants.

Comment on solubility

Solubility of Methyl 3,4,5-Trihydroxybenzoate

Methyl 3,4,5-trihydroxybenzoate, known for its aromatic structure, exhibits interesting solubility properties. Its solubility is influenced by its functional groups and overall polarity. Here’s a closer look at what affects its solubility:

  • Polarity: The presence of multiple hydroxyl groups (-OH) increases the polarity of the molecule, enhancing its solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules allows methyl 3,4,5-trihydroxybenzoate to dissolve effectively in aqueous solutions.
  • Organic Solvents: This compound is also soluble in various organic solvents, particularly those that can interact with both the aromatic and hydroxyl components.
  • Temperature Effects: Generally, solubility tends to increase with temperature, allowing for greater dissolution in warmer conditions.

In summary, "Methyl 3,4,5-trihydroxybenzoate is relatively soluble in water and organic solvents. The strength of its solubility can be largely credited to its polar characteristics and the capacity for hydrogen bonding." Thus, it finds utility in various applications, especially in organic synthesis and as a reagent in biochemical studies.

Interesting facts

Interesting Facts about Methyl 3,4,5-Trihydroxybenzoate

Methyl 3,4,5-trihydroxybenzoate, also known as methyl gallate, is a fascinating compound with several noteworthy properties and applications in various fields. Here are some intriguing facts about this compound:

1. Natural Occurrence

  • Methyl gallate is commonly found in nature, especially in plant sources such as _Eucalyptus_ and _Myrobalan_.
  • It serves as a natural product derived from gallic acid, which is part of a larger family of compounds known as tannins.

2. Antioxidant Properties

One of the primary reasons for the compound's significance is its powerful antioxidant properties. Studies have shown that methyl gallate:

  • Inhibits oxidative stress, which is a factor in the aging process.
  • Protects cells from damage caused by free radicals.

3. Medicinal Uses

Methyl 3,4,5-trihydroxybenzoate is gaining attention in the field of medicine due to its potential benefits, including:

  • Antimicrobial and antiviral effects, making it useful in treating various infections.
  • Its application in cancer research, where it has shown promise in inhibiting tumor growth.

4. Food and Cosmetic Applications

The compound is also utilized in various industries:

  • In the food industry, methyl gallate acts as a preservative due to its antimicrobial properties.
  • In cosmetics, it is valued for its skin-protective qualities and is often included in formulations for its natural antioxidant effect.

5. Research and Development

Ongoing research into methyl 3,4,5-trihydroxybenzoate continues to uncover its multifaceted applications. As noted by researchers, "methyl gallate demonstrates considerable promise in a range of therapeutic areas, warranting further exploration and study."

In summary, methyl 3,4,5-trihydroxybenzoate is not just a simple compound; it is a potent player in nature's arsenal, demonstrating countless possibilities in health, industry, and research!

Synonyms
METHYL GALLATE
Methyl 3,4,5-trihydroxybenzoate
99-24-1
Gallic acid methyl ester
Methylgallate
Benzoic acid, 3,4,5-trihydroxy-, methyl ester
Gallic acid, methyl ester
CCRIS 5567
methyl galloate
AI3-00861
3,4,5-Trihydroxy-benzoic acid methyl ester
EINECS 202-741-7
MFCD00002194
NSC 363001
UNII-623D3XG80C
BRN 2113180
623D3XG80C
NSC-363001
CHEMBL65675
3,4,5-Trihydroxybenzoic acid methyl ester
CHEBI:145828
4-10-00-01998 (Beilstein Handbook Reference)
NSC363001
M G
methyl-3,4,5-trihydroxybenzoate
GALLINCIN
Gallic acid-methyl ester
Methyl gallate (Standard)
cid_7428
SCHEMBL39513
MLS000574912
DTXSID3059189
HY-N2010R
HMS2210A23
HMS3346G16
HY-N2010
BBL010505
BDBM50187133
s3790
STL146151
AKOS000277450
GALLIC ACID METHYL ESTER [MI]
CCG-266463
FM40147
Methyl 3,4,5-trihydroxybenzoate, 98%
NCGC00247606-01
NCGC00247606-02
AC-11364
AC-34481
AS-14808
SMR000156263
SY011144
DB-057768
CS-0018330
G0017
NS00040545
EN300-393116
CS-008/03903045
Q15425833
Gallincin;NSC 363001;Methyl-3,4,5-trihydroxybenzoate
Z1255434713
InChI=1/C8H8O5/c1-13-8(12)4-2-5(9)7(11)6(10)3-4/h2-3,9-11H,1H
202-741-7