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Everolimus

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Identification
Molecular formula
C53H83NO14
CAS number
159351-69-6
IUPAC name
methyl (3R,21S,22S)-11-ethyl-4-hydroxy-12,17,21,26-tetramethyl-22-[3-oxo-3-(3,7,11,15-tetramethylhexadec-2-enoxy)propyl]-16-vinyl-7,23,24,25-tetrazahexacyclo[18.2.1.15,8.110,13.115,18.02,6]hexacosa-1,4,6,8(26),9,11,13(25),14,16,18(24),19-undecaene-3-carboxylate
State
State
Everolimus is a solid at room temperature, commonly used in its powder form for medical applications.
Melting point (Celsius)
177.20
Melting point (Kelvin)
450.30
Boiling point (Celsius)
463.40
Boiling point (Kelvin)
736.60
General information
Molecular weight
958.23g/mol
Molar mass
958.2250g/mol
Density
1.1603g/cm3
Appearence
Everolimus is typically found as a white to faintly yellow powder, with no significant odor. It is generally used in its solid form for pharmaceutical applications.
Comment on solubility

Solubility of Methyl (3R,21S,22S)-11-ethyl-4-hydroxy...

The solubility of the compound methyl (3R,21S,22S)-11-ethyl-4-hydroxy-12,17,21,26-tetramethyl-22-[3-oxo-3-(3,7,11,15-tetramethylhexadec-2-enoxy)propyl]-16-vinyl-7,23,24,25-tetrazahexacyclo[18.2.1.15,8.110,13.115,18.02,6]hexacosa-1,4,6,8(26),9,11,13(25),14,16,18(24),19-undecaene-3-carboxylate can be quite complex due to its intricate structure. Understanding the solubility characteristics requires considering several factors:

  • Polarity: The presence of various functional groups including the hydroxy and carboxylate can influence the polarity of the compound, potentially enhancing its solubility in polar solvents.
  • Chain Length: The long aliphatic chains present in the structure may reduce solubility in water but could increase solubility in organic solvents.
  • Temperature: Like many chemical compounds, solubility can be temperature-dependent. Increased temperatures might improve solubility in certain solvents.
  • Solute-Solvent Interactions: Strong interactions between the solute and solvent molecules will facilitate solubility, whereas poor interactions can hinder it.

In many cases, such complex organic compounds may exhibit limited solubility in aqueous solutions but can be more soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO). It is essential to conduct specific experimental assays to determine the precise solubility parameters for this compound, as theoretical predictions may not fully capture the nuances of solubility behavior.

As a takeaway, one could say, "Solubility is a reflection of the compound's interactions with its environment." This emphasizes the importance of the surrounding medium and the chemical structure itself in determining how well a substance dissolves.

Interesting facts

Interesting Facts about Methyl (3R,21S,22S)-11-ethyl-4-hydroxy-12,17,21,26-tetramethyl-22-[3-oxo-3-(3,7,11,15-tetramethylhexadec-2-enoxy)propyl]-16-vinyl-7,23,24,25-tetrazahexacyclo[18.2.1.15,8.110,13.115,18.02,6]hexacosa-1,4,6,8(26),9,11,13(25),14,16,18(24),19-undecaene-3-carboxylate

This unique compound stands out due to its intricate structure and diverse functional groups, showcasing the fascinating world of natural products in chemistry. Here are some interesting aspects:

  • Complex Structure: The compound features a highly elaborate polycyclic architecture, which is typical of many biologically active molecules. Its structure involves multiple rings and chiral centers, highlighting the significance of stereo-chemistry in organic compounds.
  • Biological Activity: Many compounds with similar structural motifs are known for their biological properties, including anti-inflammatory and antimicrobial activities. This raises intriguing possibilities for potential applications in pharmaceuticals.
  • Natural Origins: Compounds like this are often derived from natural sources, such as plants or fungi, where they play essential roles in ecological interactions or as secondary metabolites that deter herbivores or pathogens.
  • Applications in Materials Science: Given its unique carbon framework, researchers are exploring similar compounds in the development of new materials, particularly in areas like nanotechnology and polymer science.
  • Pioneering Research: Studies on compounds of this nature can lead to groundbreaking innovations in synthetic chemistry, paving the way for new synthetic routes and methodologies.

As a chemistry student, examining such a compound can provide invaluable insights into complexity, synthesis, and potential applications in various fields, emphasizing the limitless possibilities within chemical sciences!