Skip to main content

Methyl 4-[4-(2-fluoroethylamino)phenyl]butanoate

ADVERTISEMENT
Identification
Molecular formula
C13H18FNO2
CAS number
57342-60-4
IUPAC name
methyl 4-[4-(2-fluoroethylamino)phenyl]butanoate
State
State

At room temperature, methyl 4-[4-(2-fluoroethylamino)phenyl]butanoate is in a liquid state. Due to its chemical structure, it remains in the liquid phase over a relatively wide range of temperatures.

Melting point (Celsius)
-12.00
Melting point (Kelvin)
261.15
Boiling point (Celsius)
339.20
Boiling point (Kelvin)
612.35
General information
Molecular weight
267.31g/mol
Molar mass
267.3080g/mol
Density
1.1780g/cm3
Appearence

Methyl 4-[4-(2-fluoroethylamino)phenyl]butanoate is typically characterized as a colorless to pale yellow liquid. It is relatively clear and homogenous under standard conditions.

Comment on solubility

Solubility of Methyl 4-[4-(2-fluoroethylamino)phenyl]butanoate

Methyl 4-[4-(2-fluoroethylamino)phenyl]butanoate is a compound with intriguing solubility characteristics. Its solubility in various solvents can play a significant role in its applications and behaviors in different environments.

Some key points to consider about the solubility of this compound include:

  • Polarity: The presence of both aromatic and aliphatic structures contributes to its unique polarity, influencing solubility in polar and non-polar solvents.
  • Solventer Interaction: Methyl 4-[4-(2-fluoroethylamino)phenyl]butanoate is often more soluble in organic solvents such as ethanol and acetone compared to water, due to its hydrophobic characteristics.
  • Temperature Effects: Like many compounds, its solubility can increase with temperature; thus, heating may enhance its dissolution in solvents.
  • Structural Factors: The position of the fluorine atom and the amine group contributes to hydrogen bonding potential, which may further influence solubility.

In summary, the solubility of methyl 4-[4-(2-fluoroethylamino)phenyl]butanoate is dictated by its structural features and interactions with various solvents. Understanding these solubility properties is essential for predicting its behavior in chemical reactions and applications.

Interesting facts

Interesting Facts About Methyl 4-[4-(2-fluoroethylamino)phenyl]butanoate

Methyl 4-[4-(2-fluoroethylamino)phenyl]butanoate is a fascinating compound with notable characteristics that make it a subject of interest in various fields of research. Its structure includes a unique combination of functional groups that contribute to its reactivity and potential applications:

1. Structural Importance

  • Amine Group: The presence of the amine group in its structure can influence biological activity, making this compound interesting for medicinal chemists.
  • Fluorine Atoms: The introduction of fluorine, a highly electronegative element, often enhances the compound's lipophilicity, which can affect its ability to cross biological membranes.
  • Esters: Being an ester, the compound may undergo hydrolysis, leading to interesting reactions in various chemical environments.

2. Potential Applications

  • Pharmaceuticals: Due to its unique structure, this compound could be explored for therapeutic uses, particularly in creating drugs targeting specific biological pathways.
  • Research Tool: Its ability to interact with biological systems may serve as a useful tool in biochemical research.

3. Reaction Mechanisms

The reactivity of Methyl 4-[4-(2-fluoroethylamino)phenyl]butanoate can lead to diverse chemical transformations, making it a valuable compound for studying reaction mechanisms, such as:

  • Hydrolysis in the presence of nucleophiles.
  • Substitution reactions involving the amino moiety.

4. Synthesis and Development

The synthesis of this compound often involves multiple steps, necessitating careful planning and execution in the laboratory. Its preparation could include:

  • Aromatic Substitution: Incorporating the fluorinated amine in a stepwise manner.
  • Esters Formation: Creating the butanoate portion through esterification processes.

Overall, Methyl 4-[4-(2-fluoroethylamino)phenyl]butanoate not only holds potential for practical applications but also serves as an excellent example of the intricate design found in chemistry. Its structure alone presents a myriad of opportunities for future explorations in both academic and industrial chemistry.